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Featured San Francisco Independent Hotels

See all 540 Hotels in San Francisco
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5 (4,603 reviews)
Nice hotel but in a bad area Reader beware: the hotel itself was nice and cheap, but is in a crime ridden area(google tenderloin … - 

$169

$169
Hotel Whitcomb

Hotel Whitcomb

1231 Market St, San Francisco
3.5 out of 5.0
3.2 out of 5 (8,421 reviews)
Hotel shows the age but room was clean and staff was welcoming - 

$115

$115
Hotel Zephyr

Hotel Zephyr

250 Beach Street, San Francisco
3.5 out of 5.0
4.2 out of 5 (2,589 reviews)
This hotel is very nice and hip. The fire pits outside are awesome. They also have a game room with … - 

$161

$161
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

1550 Bayshore Hwy, Burlingame
3.5 out of 5.0
4.5 out of 5 (3,764 reviews)
Nice view and pleasant hotel The hotel is slightly older and the sheets are poly-blend (yuck!) but the light blanket was 100% co … - 

$107

$107
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

433 Powell St, San Francisco
3.5 out of 5.0
4.3 out of 5 (3,632 reviews)
Nice hotel near to Union Square Near to Union Square, clean rooms, great staff. I recomend this Hotel. - 

$161

$161
Handlery Union Square Hotel

Handlery Union Square Hotel

351 Geary St, San Francisco
4.0 out of 5.0
4.0 out of 5 (4,229 reviews)
Nice Union Square Hotel Very convenient, clean, comfortable, and quiet. The hotel restaurant was good too. - 

$149

$149
Hotel Aura SFO

Hotel Aura SFO

190 El Camino Real, San Bruno
2.5 out of 5.0
4.0 out of 5 (1,983 reviews)
Nice hotel near the interstate with easy access This was a nice hotel with easy access to the interstate and downtown San Francisco. Quiet neighbor … - 

$130

$130
Hotel Vertigo

Hotel Vertigo

940 Sutter Street, San Francisco
4.0 out of 5.0
4.0 out of 5 (1,476 reviews)
Hotel Vertigo I love the decor of the hotel. The staff was very friendly and the room was clean and comfortable. … - 

$159

$159
The Pickwick Hotel

The Pickwick Hotel

85 5th St, San Francisco
4.0 out of 5.0
3.5 out of 5 (1,899 reviews)
Price right for what you get... Terrific location, clean, comfortable. Really as good as some Euro boutique hotels. Only downside: … - 

$139

$139
Hotel Triton

Hotel Triton

342 Grant Ave, San Francisco
3.5 out of 5.0
4.2 out of 5 (1,457 reviews)
Great location It was a hassle free check in the receptionist was nice and helpful. They sent up complimentary win … - 

$141

$141
Monarch Hotel

Monarch Hotel

1015 Geary St, San Francisco
2.5 out of 5.0
3.0 out of 5 (1,947 reviews)
Nice hotel and friendly staff The hotel is in a very interesting area where there are a lot of random people (people from all wal … - 

$93

$93
Villa Florence San Francisco on Union Square

Villa Florence San Francisco on Union Square

225 Powell St, San Francisco
4.5 out of 5.0
4.0 out of 5 (3,573 reviews)
Lovely hotel in the heart of Union Square Very comfortable clean room - with nice furnishings, bathroom and fridge was a bonus. Staff vrry fr … - 

$135

$135
The Dylan at SFO

The Dylan at SFO

110 S El Camino Real, Millbrae
3.5 out of 5.0
4.1 out of 5 (2,620 reviews)
Great location and staff The staff was friendly and management has made a nice effort in adding upgrades to the facilities. … - 

$117

$117
Grant Plaza Hotel

Grant Plaza Hotel

465 Grant Ave, San Francisco
2.5 out of 5.0
3.2 out of 5 (2,046 reviews)
Chinatown Hotel The rooms were very small. I was surprised to see that the windows were open when we entered our ro … - 

$98

$98
Lombard Motor Inn

Lombard Motor Inn

1475 Lombard Street, San Francisco
3.0 out of 5.0
4.0 out of 5 (1,702 reviews)
Nice hotel close to everything Very nice I liked parking very convenient to everything good location excellent - 

$133

$133
Grant Hotel

Grant Hotel

753 Bush St, San Francisco
2.5 out of 5.0
3.6 out of 5 (2,752 reviews)
Great Location The Grant was centrally located , close to union square, Hop on buses and many restaurants. Everyth … - 

$109

$109
Hotel Focus SFO

Hotel Focus SFO

111 Mitchell Ave, South San Francisco
3.5 out of 5.0
3.1 out of 5 (456 reviews)
Quiet decent place. I won't recommend anyone to help themselves at the complimentary breakfast tho. … - 

$80

$80
Axiom Hotel San Francisco

Axiom Hotel San Francisco

28 Cyril Magnin Street, San Francisco
4.0 out of 5.0
4.4 out of 5 (627 reviews)
Overall good experience. Convenient location and great access to public transportation. Room wasn’t … - 

$176

$176
The Mosser

The Mosser

54 4th Street, San Francisco
3.0 out of 5.0
3.9 out of 5 (4,413 reviews)
Good value city centre hotel Reasonably comfortable room. Small wash basin in the corner of the room. Fitted with a shower and a … - 

$101

$101
Francisco Bay Inn

Francisco Bay Inn

1501 Lombard St, San Francisco
2.5 out of 5.0
3.4 out of 5 (1,751 reviews)
Not fancy, but not bad. Would stay again. Hotel room was outdated, furniture outdated and old. The mattress wasn't very comfortable. The room … - 

$112

$112

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Independent San Francisco Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in San Francisco, California. Known for well-appointed rooms and friendly, personalized service, each of the top Independent San Francisco hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some San Francisco Independent locations may even offer extra little benefits and discounts for frequent travelers.