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Featured San Francisco Independent Hotels

See all 543 Hotels in San Francisco
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5 (4,600 reviews)
No Expedia VIP benefits Major renovations going on at present. No VIP Expedia upgrades or mention. - 

$169

$169
Hotel Whitcomb

Hotel Whitcomb

1231 Market St, San Francisco
3.5 out of 5.0
3.2 out of 5 (8,420 reviews)
I like the location and the service overall it's okay - 

$115

$115
Hotel Zephyr

Hotel Zephyr

250 Beach Street, San Francisco
3.5 out of 5.0
4.2 out of 5 (2,584 reviews)
Nice hotel in a very convenient location. We ended up with a handicapped room. There was only the single mirror in the bathroom. We did not r … - 

$161

$161
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

1550 Bayshore Hwy, Burlingame
3.5 out of 5.0
4.5 out of 5 (3,757 reviews)
Nice hotel convenient location. Free pkg WiFi. Great easy check in at about 6pm. Nice staff, helpful, and knowledgeable. Free breakfast, WiFi, and … - 

$107

$107
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

433 Powell St, San Francisco
3.5 out of 5.0
4.3 out of 5 (3,631 reviews)
Great hotel with a Great location This hotel is ideal if you want to stay by Union square and walk around all the shops and stores. T … - 

$161

$161
Handlery Union Square Hotel

Handlery Union Square Hotel

351 Geary St, San Francisco
4.0 out of 5.0
4.0 out of 5 (4,229 reviews)
Good hotel centrally located Our stay was good the room temperature was just a little warm sometimes. - 

$149

$149
Hotel Aura SFO

Hotel Aura SFO

190 El Camino Real, San Bruno
2.5 out of 5.0
4.0 out of 5 (1,977 reviews)
Nice Hotel close to the airport Very nice hotel with good breakfast. Clean and good beds - 

$130

$130
Hotel Vertigo

Hotel Vertigo

940 Sutter Street, San Francisco
4.0 out of 5.0
4.0 out of 5 (1,476 reviews)
Hotel Vertigo I love the decor of the hotel. The staff was very friendly and the room was clean and comfortable. … - 

$159

$159
The Pickwick Hotel

The Pickwick Hotel

85 5th St, San Francisco
4.0 out of 5.0
3.6 out of 5 (1,901 reviews)
Price right for what you get... Terrific location, clean, comfortable. Really as good as some Euro boutique hotels. Only downside: … - 

$139

$139
Hotel Triton

Hotel Triton

342 Grant Ave, San Francisco
3.5 out of 5.0
4.2 out of 5 (1,453 reviews)
Boutique hotel next to Chinatown and Union Square The hotel recently changed ownership, therefore, there’s construction going on in the lobby area. T … - 

$129

$129
Monarch Hotel

Monarch Hotel

1015 Geary St, San Francisco
2.5 out of 5.0
3.0 out of 5 (1,951 reviews)
Friendly staff. Allowed to check in early. Comfortable bed. Small room but comfortable. - 

$93

$93
Villa Florence San Francisco on Union Square

Villa Florence San Francisco on Union Square

225 Powell St, San Francisco
4.5 out of 5.0
4.0 out of 5 (3,573 reviews)
Lovely hotel in the heart of Union Square Very comfortable clean room - with nice furnishings, bathroom and fridge was a bonus. Staff vrry fr … - 

$135

$135
The Dylan at SFO

The Dylan at SFO

110 S El Camino Real, Millbrae
3.5 out of 5.0
4.1 out of 5 (2,619 reviews)
Great location and staff The staff was friendly and management has made a nice effort in adding upgrades to the facilities. … - 

$117

$117
Grant Plaza Hotel

Grant Plaza Hotel

465 Grant Ave, San Francisco
2.5 out of 5.0
3.2 out of 5 (2,046 reviews)
Good location In the middle of Chinatown and with no parking garage. Tiny room in an old building - 

$98

$98
Lombard Motor Inn

Lombard Motor Inn

1475 Lombard Street, San Francisco
3.0 out of 5.0
4.0 out of 5 (1,699 reviews)
Good location, pleasant stay. The hotel was a little dated but the room was big, the bed was comfortable. We were close to a stop … - 

$133

$133
Grant Hotel

Grant Hotel

753 Bush St, San Francisco
2.5 out of 5.0
3.6 out of 5 (2,749 reviews)
Good hotel to stay in the city good location parking garage right across the street which was convi … - 

$109

$109
Hotel Focus SFO

Hotel Focus SFO

111 Mitchell Ave, South San Francisco
3.5 out of 5.0
3.1 out of 5 (454 reviews)
Hotel close to SFO Feels like an old super 8 that they are fixing up. Clean though and perfect for a quick over night … - 

$80

$80
Axiom Hotel San Francisco

Axiom Hotel San Francisco

28 Cyril Magnin Street, San Francisco
4.0 out of 5.0
4.4 out of 5 (625 reviews)
Overall good experience. Convenient location and great access to public transportation. Room wasn’t … - 

$176

$176
The Mosser

The Mosser

54 4th Street, San Francisco
3.0 out of 5.0
3.9 out of 5 (4,412 reviews)
Good value city centre hotel Reasonably comfortable room. Small wash basin in the corner of the room. Fitted with a shower and a … - 

$101

$101
Francisco Bay Inn

Francisco Bay Inn

1501 Lombard St, San Francisco
2.5 out of 5.0
3.4 out of 5 (1,751 reviews)
Not fancy, but not bad. Would stay again. Hotel room was outdated, furniture outdated and old. The mattress wasn't very comfortable. The room … - 

$112

$112
Map

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Independent San Francisco Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in San Francisco, California. Known for well-appointed rooms and friendly, personalized service, each of the top Independent San Francisco hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some San Francisco Independent locations may even offer extra little benefits and discounts for frequent travelers.