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Featured San Francisco Independent Hotels

See all 524 Hotels in San Francisco
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,539 reviews)
good location the staff was extremely friendly, rooms clean and beds are comfy. There are some homeless in the ar … - 

$188

$188
Oceano Hotel and Spa

Oceano Hotel and Spa

280 Capistrano Road, Half Moon Bay
4.0 out of 5.0
4.4 out of 5 (269 reviews)
Didn't know what to expect, pleasantly surprised. First time to Half Moon Bay. Clean, spacious room with lots of restaurants, natural beauty nearby. - 

$259

$259
Hotel G San Francisco

Hotel G San Francisco

386 Geary Street, San Francisco
4.0 out of 5.0
4.1 out of 5 (481 reviews)
Great location. Great stuff and beautifully decorated and clean rooms. Only complaint is bathroom h … - 

$271

$271
Hotel Drisco

Hotel Drisco

2901 Pacific Avenue, San Francisco
4.0 out of 5.0
4.8 out of 5 (117 reviews)
Deluxe, luxury Hotel This is probably the nicest hotel that I've ever stayed in. It might be one of the nicest hotels in … - 

$409

$409
Casa Madrona Hotel & Spa

Casa Madrona Hotel & Spa

801 Bridgeway, Sausalito
3.5 out of 5.0
4.3 out of 5 (194 reviews)
Always lovely, ideally located, rare snippy moment I stay at the Casa Madrona every time I come to SF for business/pleasure. Why bother with the busy … - 

$297

$297
Axiom Hotel San Francisco

Axiom Hotel San Francisco

28 Cyril Magnin Street, San Francisco
4.0 out of 5.0
4.4 out of 5 (154 reviews)
Great for the cable cars. The Axiom is in a great location right next to the city centre terminus for the cable cars and clos … - 

$216

$216
Villa Florence

Villa Florence

225 Powell St, San Francisco
4.0 out of 5.0
3.7 out of 5 (531 reviews)
Location is a real plus and well as the staff Have stayed here before as it is close and the staff is so friendly - 

$186

$186
Orchard Hotel

Orchard Hotel

665 Bush St, San Francisco
4.0 out of 5.0
4.5 out of 5 (808 reviews)
Francisco Charm Loved the Staff,location,comfort,cleanliness and class of this hotel. Would definitely stay here ag … - 

$224

$224
Orchard Garden Hotel

Orchard Garden Hotel

466 Bush St, San Francisco
4.0 out of 5.0
4.5 out of 5 (618 reviews)
stayed one night for marathon, bed was comfy, room was clean, staff were nice. - 

$206

$206
Cavallo Point

Cavallo Point

601 Murray Circle, Sausalito
4.5 out of 5.0
4.4 out of 5 (123 reviews)
Beautiful, relaxing, great location. Wish we could have stayed longer. Will go back! The bed was so comfy and room was good size. Ate di … - 

$489

$489
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Independent San Francisco Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in San Francisco, California. Known for well-appointed rooms and friendly, personalized service, each of the top Independent San Francisco hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some San Francisco Independent locations may even offer extra little benefits and discounts for frequent travelers.