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Featured San Francisco Independent Hotels

See all 509 Hotels in San Francisco
Hotel Whitcomb

Hotel Whitcomb

1231 Market St, San Francisco
3.5 out of 5.0
3.1 out of 5 (3,184 reviews)
CONVENIENTLY LOCATED HOTEL WAS GREAT FOR GETTING ON THE BART AND THE F TRAIN, IT WAS NICE THAT THEY HAD PARKING, BUT THE … - 

$189

$189
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,813 reviews)
The St. Francis IS San Francisco... I'm from the Bay Area but moved out of the state 20 years ago. So much has changed here (everywhere … - 

$245

$245
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,611 reviews)
Hotel Serrano was close to Union Square, big bus pickup and bike rentals. Around 10 minute walk to … - 

$208

$208
Hotel Zoe San Francisco

Hotel Zoe San Francisco

425 North Point, San Francisco
4.0 out of 5.0
4.2 out of 5 (2,355 reviews)
Very nice hotel Hotel was very nice, within walking distance to Old Town Sacramento. Great Location to walk around … - 

$203

$203
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.0 out of 5.0
4.0 out of 5 (1,267 reviews)
Great stay Staff were fantastic and helpful. Restaurant was good and not overpriced. Only negative was that on … - 

$179

$179
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

1550 Bayshore Hwy, Burlingame
3.0 out of 5.0
4.5 out of 5 (2,126 reviews)
Nice hotel, convenient to the airport and BART This hotel is a great value, with very large, comfortable rooms, a great, accommodating staff, espe … - 

$143

$143
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
4.3 out of 5 (2,753 reviews)
Excellent service great location near everything Will stay again. - 

$194

$194
Fairmont San Francisco

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco
5.0 out of 5.0
4.4 out of 5 (2,053 reviews)
Atop Beautiful Nob Hill While we had an interior view room, there are so many great views from everywhere you go around nea … - 

$280

$280
Hotel Zephyr

Hotel Zephyr

250 Beach Street, San Francisco
3.5 out of 5.0
4.1 out of 5 (876 reviews)
Close to the Wharf We enjoyed our stay. Nice decor. It was within walking distance of all the places we wanted to see, … - 

$220

$220
Pier 2620 Hotel Fisherman's Wharf

Pier 2620 Hotel Fisherman's Wharf

2620 Jones Street, San Francisco
3.5 out of 5.0
4.2 out of 5 (1,908 reviews)
Hotel Staffers We were honored with the best staffers at the front counter RICK I believe is his name a retired Ar … - 

$220

$220
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

424 Clay St, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,407 reviews)
Great location awesome staff! Nice clean room with everything we needed! I would for sure stay here … - 

$161

$161
San Francisco Marriott Marquis

San Francisco Marriott Marquis

780 Mission Street, San Francisco
4.0 out of 5.0
4.4 out of 5 (1,641 reviews)
Nice Stay, Decent Service Too long a wait to check in with so many staff working at 8 pm Sunday night. Place was not that bus … - 

$199

$199
Handlery Union Square Hotel

Handlery Union Square Hotel

351 Geary St, San Francisco
3.5 out of 5.0
3.9 out of 5 (1,581 reviews)
Great hotel in a great location Walking distance to a lot of restaurants, Walgreens and shops. Could walk to Chinatown but its hill … - 

$199

$199
Grand Hyatt San Francisco Union Square

Grand Hyatt San Francisco Union Square

345 Stockton St, San Francisco
4.0 out of 5.0
4.3 out of 5 (1,365 reviews)
Great place next to everything Had a great stay while visiting San Francisco. Hotel is clise to Union Square and public transporta … - 

$229

$229
Red Roof PLUS+ San Francisco Airport

Red Roof PLUS+ San Francisco Airport

777 Airport Blvd, Burlingame
3.0 out of 5.0
3.4 out of 5 (1,008 reviews)
ccomfort, even though we checked out we were still able to use the airport shuttle pool and shower … - 

$121

$121
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St, San Francisco
5.0 out of 5.0
4.5 out of 5 (1,535 reviews)
Wouldn't hesitate to recommend this wonderful hotel. Staff are excellent and willing to go the extr … - 

$235

$235
San Francisco Marriott Union Square

San Francisco Marriott Union Square

480 Sutter Street, San Francisco
4.0 out of 5.0
4.3 out of 5 (765 reviews)
Great location We stayed 3 nights. The room is starting to look a little dated but still lovely, bathroom good siz … - 

$209

$209
Hotel Kabuki - a Joie de Vivre Boutique Hotel

Hotel Kabuki - a Joie de Vivre Boutique Hotel

1625 Post St, San Francisco
3.5 out of 5.0
4.1 out of 5 (1,100 reviews)
Fun Hotel, complimentary wine! We've enjoyed this hotel before and had a great time again. Staff super friendly and accommodating. … - 

$151

$151
Bartlett Bunkhouse

Bartlett Bunkhouse

240 O'Farrell St, San Francisco
2.5 out of 5.0
3.9 out of 5 (30 reviews)
Good location near to everything It's a good place for those who want to explore San Francisco, public transportation, bars, restaur … - 

$129

$129
Map

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Independent San Francisco Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in San Francisco, California. Known for well-appointed rooms and friendly, personalized service, each of the top Independent San Francisco hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some San Francisco Independent locations may even offer extra little benefits and discounts for frequent travelers.