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Your San Francisco Vacation
San Francisco is calling your name! Whatever type of break you're planning, you can immerse yourself in the best of this neighborhood with a San Francisco vacation package. Wondering what to see and do during your trip to San Francisco? Nearby attractions such as San Juan Gate, La Fortaleza and Catedral Basilica Menor de San Juan Bautista are good places to begin. Whatever your travel plans or budget, booking the ultimate San Francisco vacation is easy with Expedia.
The Latest San Francisco Vacation Packages

Serena Boutique Hotel
Reviewed on Nov 29, 2025



ESJ Beach Hotel
Reviewed on Nov 30, 2025

Hotel Puerto Valdes
Reviewed on Nov 24, 2025
Where to stay in San Francisco

Old San Juan
The fascinating museums and captivating waterfront views are top of the list for many visitors to Old San Juan. A stop by Port of San Juan or Pier 4 might round out your trip.
San Francisco Hotel Deals

Hotel Milano
Room is spotless with a very modern aesthetic. Air conditioning works well, and the bed was very comfortable.
Reviewed on Nov 28, 2025

Alma San Juan
Friendly and helpful staff, clean rooms and boutique feel.
Reviewed on Nov 26, 2025

CasaBlanca Hotel
The staff were really friendly. We'll be back.
Reviewed on Nov 26, 2025
Discover the most popular places to visit in San Francisco

Plaza de Colon
You can find out about the history of San Juan with a visit to Plaza de Colon. Wander the area's beautiful beaches or simply enjoy one of its top-notch restaurants.
Museo del Mar
You can browse the exhibits at Museo del Mar, a museum with a storied past, during your trip to San Juan. Discover the area's top-notch restaurants and its acclaimed art scene.
Teatro Tapia
Enjoy a performance at Teatro Tapia, a storied theater in San Juan. Wander the beautiful beaches and seaside in the area.
Things to do

Night Kayak - Condado City Lights Tour

Puerto Rico: UTV and Can-Am Sightseeing Tours
























