San Francisco Vacations from $504

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Your San Francisco Vacation

San Francisco is calling your name! Whatever type of break you're planning, you can immerse yourself in the best of this neighborhood with a San Francisco vacation package. Wondering what to see and do during your trip to San Francisco? Nearby attractions such as San Juan Gate, La Fortaleza and Catedral Basilica Menor de San Juan Bautista are good places to begin. Whatever your travel plans or budget, booking the ultimate San Francisco vacation is easy with Expedia.

The Latest San Francisco Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Serena Boutique Hotel
OLV Fifty Five - Adults Only
Isla Verde Beachfront Retreat With Parking
ESJ Beach Hotel
Hotel Puerto Valdes

Black Friday Sale

Limited-time deals: Save up to 50% on select hotels.

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about San Francisco

San Francisco Hotel Deals

Hotel Milano

Hotel Milano

2 out of 5
307 Calle Fortaleza San Juan San Juan
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $148 total per night from Dec 2 to Dec 3
$148 total
Dec 2 - Dec 3
Total with taxes and fees
9/10 Wonderful! (112 reviews)
Room is spotless with a very modern aesthetic. Air conditioning works well, and the bed was very comfortable.

Reviewed on Nov 28, 2025

Hotel Milano
Alma San Juan

Alma San Juan

4 out of 5
405 C. de San Francisco San Juan San Juan
Fully refundableReserve now, pay when you stay
$186 nightly
The price is $203 total per night from Dec 1 to Dec 2
$203 total
Dec 1 - Dec 2
Total with taxes and fees
9/10 Wonderful! (306 reviews)
Friendly and helpful staff, clean rooms and boutique feel.

Reviewed on Nov 26, 2025

Alma San Juan
CasaBlanca Hotel

CasaBlanca Hotel

3.5 out of 5
316 Calle Fortaleza San Juan
Fully refundableReserve now, pay when you stay
$164 nightly
The price is $179 total per night from Dec 1 to Dec 2
$179 total
Dec 1 - Dec 2
Total with taxes and fees
8.6/10 Excellent! (1,472 reviews)
The staff were really friendly. We'll be back.

Reviewed on Nov 26, 2025

CasaBlanca Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in San Francisco

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.