San Niccolò Vacations from $943

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Your San Niccolò Vacation

Take the stress out of organizing your next escape by booking a San Niccolò vacation package. Soak in the sounds and sights of this wonderful neighborhood and enjoy what it has to offer. Some leading nearby attractions to see during your trip to San Niccolò include Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Stop daydreaming and start doing. When you're ready to lock in your next vacation to San Niccolò, Expedia will help get you there.

The Latest San Niccolò Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Aurum Uffizi

Aurum Uffizi

4 out of 5
Historic Centre of Florence
Save 100% on your flight
per person
Oct 9 - Oct 14
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.8/10 Good! (1,001 reviews)
Very well connected. Room size Good for Family of 4. AC was not very efficient in room, Kind of slow. Rest ok Even breakfast included which is good for wallet

Reviewed on Jul 25, 2025

Villa di Piazzano - Small Luxury Hotel of the World

Villa di Piazzano - Small Luxury Hotel of the World

5 out of 5
Save 100% on your flight
per person
Oct 4 - Oct 11
found 9 hours ago
Roundtrip flight included
New York (JFK) to Florence (FLR)
9.8/10 Exceptional! (211 reviews)
AMAZING! Gorgeous! I would recommend to everyone!

Reviewed on Jul 29, 2025

Hotel Number Nine

Hotel Number Nine

5 out of 5
Historic Centre of Florence
Save 100% on your flight
per person
Oct 5 - Oct 10
found 13 hours ago
Roundtrip flight included
New York (JFK) to Florence (FLR)
9.6/10 Exceptional! (1,000 reviews)
Incredible hotel with attention to every detail

Reviewed on Jul 18, 2025

Aurum Firenze

Aurum Firenze

4 out of 5
Historic Centre of Florence
Save 100% on your flight
per person
Sep 17 - Sep 23
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.6/10 Good! (1,012 reviews)
The property is very centrally located—just a short walk from the Duomo and the central train station, with easy access to the tram as well. I was pleasantly surprised by how convenient the location was. The staff were friendly, and the included breakfast was a nice way to start the day with a quick bite. The only suggestion I’d make is to provide a thicker blanket for added comfort.

Reviewed on Jul 29, 2025

The Moon Boutique Hotel & Spa

The Moon Boutique Hotel & Spa

4 out of 5
Historic Centre of Florence
Save 100% on your flight
per person
Oct 9 - Oct 14
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.6/10 Exceptional! (462 reviews)
Hands down the best place we have stayed. They accommodated to go breakfasts for our tours, arranged taxis, made cappuccino when we were heading out the door. Wonderful experience

Reviewed on Jun 6, 2025

Where to stay in San Niccolò

Find the best San Niccolò areas and neighborhoods for the activities you enjoy most. Learn more about San Niccolò
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

San Niccolò Hotel Deals

Numa Palazzo San Niccolò

Numa Palazzo San Niccolò

VIA DI SAN NICCOLO, 79, Florence, FI
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $162 total per night from Aug 5 to Aug 6
$162 total
Aug 5 - Aug 6
Total includes taxes and fees
9.4/10 Exceptional! (157 reviews)
"One of the best places we stayed in Italy. It was super clean. Beds are comfortable and bathrooms are spacious. They have a beautiful garden. Check-in and check-out is a breeze. They have luggage storage. We were able to do our laundry. It is within walking distance from the train station (about ..."

Reviewed on Jul 14, 2025

Numa Palazzo San Niccolò
The Social Hub Florence Lavagnini

The Social Hub Florence Lavagnini

4 out of 5
Viale Spartaco Lavagnini 70 72, Florence, FI
Fully refundable
$95 nightly
The price is $121 total per night from Aug 24 to Aug 25
$121 total
Aug 24 - Aug 25
Total includes taxes and fees
8.8/10 Excellent! (1,091 reviews)
"Great food options, perfect location to a wide variety of places, staff were amazing as well as the facilities."

Reviewed on Jul 29, 2025

The Social Hub Florence Lavagnini
c-hotels Ambasciatori

c-hotels Ambasciatori

4 out of 5
Via Luigi Alamanni 3, Florence, FI
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $151 total per night from Aug 24 to Aug 25
$151 total
Aug 24 - Aug 25
Total includes taxes and fees
8.2/10 Very Good! (1,001 reviews)
"It was very safe and convenient."

Reviewed on Jul 23, 2025

c-hotels Ambasciatori
See all 10,888 properties in San Niccolò
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in San Niccolò

Before sunset.. Sweet golden light kissing the Florence

Giardino Bardini

You can learn about the history of Florence when you stop by Giardino Bardini. Wander the riverfront or discover the area's beautiful sunsets.

Giardino Bardini
cannoli siciliani freschissimi

CLET

Find out about the history of Florence with a stop at CLET. Discover the area's fascinating museums and stunning cathedral.

CLET

Giardino degli Iris

Enjoy the beautiful sunsets and explore Giardino degli Iris, a lovely green space in Florence. Add the area's churches or notable monuments to your travel plans.

Giardino degli Iris

Things to do

Florence: Pasta Cooking Class with Unlimited Wine

Florence: Pasta Cooking Class with Unlimited Wine

$34
per adult
90% of travellers recommend
Florence: Pasta Cooking Class with Unlimited Wine
Say "TIPSY"!

Tipsy Tour: Fun Bar Crawl In Florence with Local Guide

$76
per adult
100% of travellers recommend
Tipsy Tour: Fun Bar Crawl In Florence with Local Guide
Explore Florence’s nightlife with drinks & history

Night Out in Florence: Bar Crawl and City Walk

$70
per adult
Night Out in Florence: Bar Crawl and City Walk
See all activities in Florence
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.