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Find hotels by Destination Hotels in San Ysidro, CA

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Compare rooms and suites by Destination Hotels in San Ysidro with rates, reviews, and availability. Most hotels are fully refundable.

Destination Hotels San Ysidro Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Destination Hotels hotels in San Ysidro, California. Known for well-appointed rooms and friendly, personalized service, each of the top Destination Hotels San Ysidro hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some San Ysidro Destination Hotels locations may even offer extra little benefits and discounts for frequent travelers.

Recent reviews of San Ysidro hotels
Expedia verified reviews

The Dana on Mission Bay

The Dana on Mission Bay

5/5 Excellent
Great family hotel.
"My family and I loved the hotel. Nice rooms, and a nice restaurant with good food and drinks (though service was a tad slow). Two nice pools with easy access from our room. Close to everything and it is nice to walk around the area. "
A verified traveler stayed at The Dana on Mission Bay
Posted 8 hours ago
The Dana on Mission Bay