Sancti Spiritus Vacations from $823

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

The Latest Sancti Spiritus vacation packages

Price found within the past 48 hours. Click for updated prices.
Sercotel Gran Hotel Conde Duque

Sercotel Gran Hotel Conde Duque

4 out of 5
Chamberí
Price was $1,266, price is now $823 per person
$823
per person
Feb 3 - Feb 6
found 1 day ago
Roundtrip flight included
San Juan (SJU) to Madrid (MAD)
8.6/10 Excellent! (960 reviews)
Excellent customers service, great atmosphere, room cleanness

Reviewed on Dec 6, 2025

Ikonik Gran Via

Ikonik Gran Via

4 out of 5
Madrid Centro
Save 100% on your flight
Price was $1,832, price is now $1,297 per person
$1,297
per person
Feb 12 - Feb 18
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Madrid (MAD)
9.2/10 Wonderful! (103 reviews)
The hotel is small hard to find.

Reviewed on Dec 26, 2025

Hotel Quatro Puerta Del Sol

Hotel Quatro Puerta Del Sol

4 out of 5
Madrid Centro
Save 100% on your flight
Price was $1,488, price is now $1,071 per person
$1,071
per person
Feb 12 - Feb 18
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Madrid (MAD)
8.6/10 Excellent! (1,000 reviews)
The room was clean, quiet. The location was great, right across from The Four Seasons, the staff was helpful.

Reviewed on Nov 26, 2025

The First One Madrid Preciados

The First One Madrid Preciados

3 out of 5
Madrid Centro
Save 100% on your flight
Price was $1,498, price is now $1,080 per person
$1,080
per person
Feb 12 - Feb 18
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Madrid (MAD)
9/10 Wonderful! (824 reviews)
Great room, excellent service

Reviewed on Dec 31, 2025

UMusic Hotel Madrid

UMusic Hotel Madrid

5 out of 5
Madrid Centro
Save 100% on your flight
Price was $1,749, price is now $1,336 per person
$1,336
per person
Feb 12 - Feb 18
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Madrid (MAD)
9.4/10 Exceptional! (758 reviews)
Loved this hotel! Such a vibe

Reviewed on Dec 16, 2025

Don't see what you're looking for?
See all available trips from Columbus to Sancti Spiritus
View all trips

Sancti Spiritus Hotel Deals

Casa rural del labrador, a home to enjoy your family and friends.

Casa rural del labrador, a home to enjoy your family and friends.

Sancti-Spíritus
Get rates
Casa rural del labrador, a home to enjoy your family and friends.
Crisol Conde Rodrigo

Crisol Conde Rodrigo

3 out of 5
PLAZA SAN SALVADOR,7 Ciudad Rodrigo
Fully refundableReserve now, pay when you stay
$53 nightly
The price is $59 total per night from Jan 1 to Jan 2
$59 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
8.6/10 Excellent! (97 reviews)
Great, friendly hotel in a perfect location.
Lovely hotel right in the middle of medieval Cuidad Rodrigo. Perfectly located, fantastic, friendly and helpful staff and a great breakfast. Our only negative was that the view from our room was a wall and it was a bit tired.

Reviewed on Oct 10, 2025

Crisol Conde Rodrigo
Hotel Conde Rodrigo II by eme hoteles

Hotel Conde Rodrigo II by eme hoteles

4 out of 5
HUERTA LAS VIÑAS Ciudad Rodrigo
$40 nightly
The price is $44 total per night from Jan 20 to Jan 21
$44 total
Jan 20 - Jan 21, 2026
Total with taxes and fees
8.6/10 Excellent! (54 reviews)
Fantastic hotel, but the air conditioning had limited control, meaning we had to go to reception at 3am to get it switched back on as the room was very hot. Restaurant is superb quality, not cheap but worth treating yourself, the tiramasu is an experience.

Reviewed on May 22, 2025

Hotel Conde Rodrigo II by eme hoteles
See all 114 properties in Sancti Spiritus
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Sancti Spiritus Vacation Packages

Sancti Spiritus Essential Information

Language
Spanish
Currency
Euros
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
960
Max Temp Winter
50ºF
Max Temp Summer
80ºF

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Sancti Spiritus vacation package cost?
You'll find cheap prices from $823 on Expedia for your Sancti Spiritus break. However, factors like the length of stay, hotel choice and season will determine how much your vacation to Sancti Spiritus costs.
What are the cheapest months to go to Sancti Spiritus?
November, December and January are great times to look for cheap Sancti Spiritus vacation packages. Choosing to travel in less busy periods means you can usually find lower prices on hotels and flights.
How many days is enough for Sancti Spiritus?
The ideal duration for your Sancti Spiritus vacation depends on what you'd like to see. Typically, a handful of days to a week will give you enough time to hit all the top sights and explore some hidden treasures along the way.
How to find the best Sancti Spiritus package deals?
Use Expedia's filter tool to help you find some great Sancti Spiritus package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your escape for midweek, or search for Sancti Spiritus package deals in the off-season. Switch up your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to book your vacation package as early as possible.
Is it cheaper to book a Sancti Spiritus vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your flight, car rental and hotel into one great-value price and enjoy significant savings. You'll generally get a better deal than booking each component individually. And you'll still enjoy the flexibility to create a tailored Sancti Spiritus vacation by choosing your favorite accommodation type, airline and car class.
When to book a vacation package to Sancti Spiritus?
Secure amazing discounts by booking your flights ahead of time with Expedia. If spontaneity is more your thing, snap up one of our last-minute deals for an impromptu Sancti Spiritus break.
Does Expedia offer Book Now, Pay Later Sancti Spiritus vacation packages?
If you're anything like us, you love traveling the world but don't love the big price tag that can sometimes come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the total cost of your Sancti Spiritus break over 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure great vacation packages with payment plans as soon as you spot them.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.