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Find hotels in Santa Ana, Cusco

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Discover Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hilton Garden Inn Cusco

3.5 star property
Santa Ana
9.2 out of 10, Wonderful, (1002)
"Great hotel. Best we stayed at in Cusco. Would stay again"
United States
William
$123 nightly
The price is $123
Dec 15 - Dec 16
Hilton Garden Inn Cusco

ZEVEN HOUSE - CUSCO APARTMENT

2.0 star property
Santa Ana
10.0 out of 10, Exceptional, (1)
"My wife and I are visiting Cusco from Dallas, Texas. We had a wonderful stay. The host spoke English and was very kind and helpful. He showed us how to operate the appliances. There was hot water in the shower, a gas stove, washing machine, refrigerator, TV with Netflix (big plus), and electric portable space heater (another big plus). The beds were very comfortable and warm. Wi-fi was fast and reliable. The place was quiet at night. Short walking distance to Orion grocery store. Definitely...
United States
Andrew
$50 nightly
The price is $50
Dec 8 - Dec 9
ZEVEN HOUSE - CUSCO APARTMENT

Hotel Cusco Pacha Inti

3.0 star property
Santa Ana
6.0 out of 10, (1)
"El hotel cumple con sus funciones, sin embargo es complicado el tema de la regadera, considero es un punto que pueden mejorar. El hotel no está alejado del centro pero está en una zona no tan cómoda de llegar, ni siquiera los autos tienen accedió tan fácil. El personal es muy atento y amable, sin embargo tuve que pagar dos veces la reservación porque a ellos "no se les reflejaba" siendo que ellos mismos confirmaron que tienen problemas con expedis y Booking y a pesar de que les mostré en mi...
Mexico
CR
$29 nightly
The price is $29
Dec 23 - Dec 24
Hotel Cusco Pacha Inti

Tierra Viva Cusco Saphi

3.0 star property
Santa Ana
9.4 out of 10, Exceptional, (499)
"Great place ! "
United States
Roger
Tierra Viva Cusco Saphi

Munay Ñusta Cusco

3.0 star property
Santa Ana
9.6 out of 10, Exceptional, (4)
"Very nice property"
United States
Arthur
$50 nightly
The price is $50
Dec 9 - Dec 10
Munay Ñusta Cusco

Santa Ana Departamentos

2.0 star property
Santa Ana
9.0 out of 10, Wonderful, (4)
"Grand appartement à 10 min à pied de la place des Armes. Il y a également un bus qui s'arrête devant le portail. Nous sommes toujours descendus à pied et remontés en navette. Eau chaude, appartement un peu froid mais pas insurmontable. Accueil très sympathique et agréable de la part des propriétaires, n'hésitez pas à leur demander conseils ou de l'aide ils feront tout pour vous aider. Nous avons passé un excellent séjour grâce à eux."
France
Mélissa
Santa Ana Departamentos

Anata Hostel

3.0 star property
Santa Ana
8.8 out of 10, Excellent, (22)
"Great location, staff incredible!"
Canada
christiane
$22 nightly
The price is $22
Jan 2 - Jan 3, 2026
Anata Hostel

Centro by Casa Andina Cusco Saphi

3.0 star property
Santa Ana
9.0 out of 10, Wonderful, (12)
"A pleasant place to visit Cuzco"
France
Michel
Centro by Casa Andina Cusco Saphi

Munay Cusco

2.0 star property
Santa Ana
$18 nightly
The price is $18
Dec 8 - Dec 9
Munay Cusco

Hotel Mamasara

3.0 star property
Santa Ana
8.4 out of 10, Very Good, (18)
"It was nice"
United States
Alexander
$40 nightly
The price is $40
Dec 28 - Dec 29
Hotel Mamasara

Casa Karmenka

2.5 star property
Santa Ana
Casa Karmenka

Hotel El Mirador de Santa Ana

3.0 star property
Santa Ana
$32 nightly
The price is $32
Dec 8 - Dec 9
Hotel El Mirador de Santa Ana

HOSTAL LA RASA

2.0 star property
Santa Ana
10.0 out of 10, Exceptional, (1)
"Accueil très agréable !"
France
Lia
$18 nightly
The price is $18
Dec 8 - Dec 9
HOSTAL LA RASA

Tucan Hostel

2.0 star property
Santa Ana
8.4 out of 10, Very Good, (14)
"We found this hostel to be a very special place, filled with wonderfully helpful and pleasant folks. We would highly recommend a stay."
United States
Anonymous traveler
$28 nightly
The price is $28
Jan 7 - Jan 8, 2026
Tucan Hostel

JW Marriott El Convento Cusco

5.0 star property
Cusco Historic Center, 0.7 mi from Santa Ana
9.6 out of 10, Exceptional, (1002)
"We really liked the breakfast and the staffs were very helpful and friendly "
United States
Min
$338 nightly
The price is $338
Jan 4 - Jan 5, 2026
JW Marriott El Convento Cusco

Casa Andina Premium Cusco

4.0 star property
San Blas, 0.9 mi from Santa Ana
9.2 out of 10, Wonderful, (1000)
"The hotel was excellent, great staff, great breakfast, clean and Central"
United States
Lenda
$137 nightly
The price is $137
Dec 9 - Dec 10
Casa Andina Premium Cusco

Palacio Manco Capac by Ananay Hotels

4.5 star property
San Cristóbal, 0.5 mi from Santa Ana
9.6 out of 10, Exceptional, (324)
"Beautiful rooms and grounds. Staff are incredibly friendly and helpful. Breakfast is fantastic. "
United Kingdom
Ryan
$111 nightly
The price is $111
Dec 11 - Dec 12
Palacio Manco Capac by Ananay Hotels

Xima Exclusive Cusco

3.5 star property
Cusco Historic Center, 1.1 mi from Santa Ana
8.6 out of 10, Excellent, (162)
"Service, room, breakfast, dinner, area, restaurants, All great!! walkable and Uber easy location. "
United States
Albert
Xima Exclusive Cusco

Novotel Cusco

4.0 star property
Cusco Historic Center, 0.7 mi from Santa Ana
9.4 out of 10, Exceptional, (1001)
"Amazing place to stay! "
United States
Giovanna
$125 nightly
The price is $125
Dec 22 - Dec 23
Novotel Cusco

Tocuyeros Boutique Hotel

4.0 star property
San Blas, 0.7 mi from Santa Ana
9.8 out of 10, Exceptional, (386)
"Great little hotel, incredible view of the city, friendly and helpful staff. "
United States
Brian
$162 nightly
The price is $162
Dec 8 - Dec 9
Tocuyeros Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Cusco Historic Center

Explore museums like Museo de Arte Precolombino and savor fusion and neo-Andean cuisine at local restaurants. Stroll through the artisan-filled San Blas neighborhood for a picturesque shopping experience.

San Blas

Take a walk through the heart of Cusco’s artisan district, one of the city’s most beguiling and lively areas.

San Cristóbal

While visiting San Cristóbal, you might make a stop by sights like Pre-Columbian Art Museum and Plaza de las Nazarenas.

Santiago

When in Santiago, you can plan a visit to Ttio Market and Santiago Plaza, some noteworthy sights in the nearby area.

Santa Monica

Santa Monica might not have many top sights, but Real Plaza Cusco and Ttio Market are two attractions nearby that you can check out.

Top Santa Ana Hotel Reviews

Frequently asked questions

What are the best spa hotels in Santa Ana?
For a rejuvenating stay in Santa Ana, the Hilton Garden Inn Cusco is an excellent choice, boasting a stellar review score of 9.2. This hotel offers accessible spa amenities, ensuring that relaxation is within reach for all guests. With a inviting space and attentive service, it's the superb retreat for travelers looking to unwind after a day of adventure.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Santa Ana hotel for you.
How can I save on a Santa Ana hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Santa Ana hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santa Ana hotel?
Hotel prices in Santa Ana often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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