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Featured Santa Cruz Independent Hotels

See all 77 Hotels in Santa Cruz
Radisson Hotel Santa Cruz

Radisson Hotel Santa Cruz

Avenida Segunda 4, Santa Cruz
4.5 out of 5.0
4.7 out of 5 (33 reviews)
Lovely gem between the city and nature Beautiful area for one of the newest hotels in town. My elderly mother and I felt at home and bette … - 

$103

$103
Senses Boutique Hotel

Senses Boutique Hotel

Calle 24 de Septiembre, Esq. Sucre No 5, Santa Cruz
4.0 out of 5.0
4.0 out of 5 (141 reviews)
Great central location The hotel is in a great location next to the main square and all the shops and cafes. The hotel is … - 

$65

$65
Sun Hotel

Sun Hotel

Av. Banzer Km 13, Santa Cruz
4.0 out of 5.0
4.0 out of 5 (34 reviews)
Nice hotel but way overrated. Overall, I had an 'OK' experience in this hotel. The hotel is way overrated, thus too pricey for th … - 

$130

$130
Hotel LP Equipetrol

Hotel LP Equipetrol

Dr Victor Pinto, Equipetrol, Santa Cruz
4.0 out of 5.0
3.9 out of 5 (44 reviews)
Nice hotel, close to Shopping Mall The hotel offers the necessary conditions to be comfortable for people not demanding. There is no a … - 

$64

$64
Camino Real Hotel

Camino Real Hotel

Av. San Martín y 4to. Anillo, Santa Cruz
4.5 out of 5.0
4.2 out of 5 (158 reviews)
Nice Hotel close to Ventura mall. Clean room , professional and great service. Comfortable room - 

$125

$125
Hotel Las Palmas

Hotel Las Palmas

Av. El Trompillo, 604, Santa Cruz
3.5 out of 5.0
4.1 out of 5 (30 reviews)
Great hotel Staff was very friendly and helpful. Only problem I had was my room was close to a gas station at t … - 

$54

$54
Hotel Cortez

Hotel Cortez

Av. Cristobal de Mendoza 280, Santa Cruz
4.0 out of 5.0
4.4 out of 5 (16 reviews)
Nice hotel We always like staying there , very clean nice location, close to coffee shops - 

$121

$121
Terranova Suites

Terranova Suites

7º Anillo 400 mts al Oeste de, Santa Cruz
4.0 out of 5.0
4.1 out of 5 (27 reviews)
Impressed & Good Value Was impressed when opened my room's door. I booked a one-bedroom room, but got more of a suite as t … - 

$64

$64
Los Tajibos Hotel And Convention Center

Los Tajibos Hotel And Convention Center

Ave. San Martin, #455, Santa Cruz
5.0 out of 5.0
4.3 out of 5 (61 reviews)
Great hotel in Santa Cruz Business room are nice, good space to rest and work. Great location. - 

$130

$130
Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro

Av.Ejercito Nacional 290, Santa Cruz
3.5 out of 5.0
3.8 out of 5 (207 reviews)
Walkable to the main Plaza Picked us up at the airport at 4am. Terrific! Room and bathroom spacious and clean and staff very h … - 

$57

$57
Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique

Pari, 70, Santa Cruz
4.0 out of 5.0
4.5 out of 5 (13 reviews)
Nice, little boutique hotel Loved the decoration and the room, very comfortable. Nice amenities, complementary soft drinks in t … - 

$55

$55
La Quinta Apart Hotel

La Quinta Apart Hotel

Calle Aruma s/n, Barrio Urbari, Santa Cruz
4.0 out of 5.0
4.8 out of 5 (5 reviews)
Spacious hotel with beautiful pool There were two floors to our apartment hotel and a kitchen facilities. The bedrooms were spacious w … - 

$70

$70
Hotel La Siesta

Hotel La Siesta

Calle Vallegrande, 17, Santa Cruz
3.5 out of 5.0
4.1 out of 5 (8 reviews)
Decent hotel Nice hotel. Great location. Excellent friendly staff. All the staff member of this hotel is kind & … - 

$47

$47
Nomad Hostel

Nomad Hostel

Calle Velasco 316, Santa Cruz
2.5 out of 5.0
1.0 out of 5 (1 reviews)
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

San Martin Avenue Esq Street E - E, Santa Cruz
4.0 out of 5.0
4.4 out of 5 (50 reviews)
Service was great, just have to watch the inflated taxi charges. - 

$77

$77
Prince Hotel

Prince Hotel

Calle Pauro 64, Corner of, Santa Cruz
4.0 out of 5.0
4.1 out of 5 (17 reviews)
Brand new hotel, very clean, spacious room and comfy bed. Fast check in - 

$56

$56
Apart Hotel Buen Retiro

Apart Hotel Buen Retiro

Calle Florida 432, Santa Cruz
3.0 out of 5.0

$22

$22
House Inn Apart Hotel

House Inn Apart Hotel

c. Colón Nro. 643, Santa Cruz
4.0 out of 5.0
3.6 out of 5 (16 reviews)
Worth every penny! Had a super stay! From the moment a taxi sent by the hotel picked me up at the airport until I left … - 

$54

$54
Suites Toborochi

Suites Toborochi

Jaime Freyre 7, Santa Cruz
4.0 out of 5.0
4.1 out of 5 (21 reviews)
Great place to stay while in Santa Cruz The rooms are very spacious and the rest of the facilities are very well maintained, you feel like … - 

$103

$103
Colpa Caranda Eco Resort

Colpa Caranda Eco Resort

Km 32.5, Carretera al Norte, La Belgica
3.5 out of 5.0
1.0 out of 5 (1 reviews)
Map

Recently booked Santa Cruz hotels

Inboccalupo Apart Boutique
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Los Tajibos Hotel And Convention Center
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Last booking: 31 hours ago

Independent Santa Cruz Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Santa Cruz, Bolivia. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Santa Cruz hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Santa Cruz Independent locations may even offer extra little benefits and discounts for frequent travelers.