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Our top choices for Santa Cruz hotels

Hotel Santiago de Arma

Hotel Santiago de Arma
3.0 star property
Rionegro
9.2 out of 10, Wonderful, (956 reviews)
"Amazing stay close to airport n good restaurants "
United States
Juan
$107 nightly
The price is $107
May 18 - May 19
Hotel Santiago de Arma

Isak Hotel & Golf Airport

Isak Hotel & Golf Airport
3.0 star property
Rionegro
9.2 out of 10, Wonderful, (678 reviews)
"Great service restaurants nearby clean rooms close to airport with golf course as well.great stay!"
United States
Garret
$65 nightly
The price is $65
May 19 - May 20
Isak Hotel & Golf Airport

Hotel Lagoon

Hotel Lagoon
3.5 star property
Rionegro
9.2 out of 10, Wonderful, (344 reviews)
"Great breakfast"
United States
Max
$106 nightly
The price is $106
May 26 - May 27
Hotel Lagoon

Movich Hotel Las Lomas

Movich Hotel Las Lomas
4.0 star property
Rionegro
9.0 out of 10, Wonderful, (1,002 reviews)
"Great location near A"
United States
nadim
$141 nightly
The price is $141
Jun 7 - Jun 8
Movich Hotel Las Lomas

Autenthico Sajonia Hotel Aeropuerto

Autenthico Sajonia Hotel Aeropuerto
2.0 star property
Rionegro
9.4 out of 10, Exceptional, (79 reviews)
"Really nice place with beautiful views. Friendly people."
United States
Miguel
$54 nightly
The price is $54
May 18 - May 19
Autenthico Sajonia Hotel Aeropuerto

Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites
3.5 star property
Rionegro
8.4 out of 10, Very Good, (473 reviews)
"GOOD PLACE TO STAY THE NIGHT NEAR THE AIRPORT"
United States
Robert
$67 nightly
The price is $67
May 18 - May 19
Travelers Rio Verde Living Suites

Marquee Hotel

Marquee Hotel
4.0 star property
El Poblado
9.2 out of 10, Wonderful, (211 reviews)
"Great location and staff. I would stay here again. "
United States
James
$113 nightly
The price is $113
Jun 1 - Jun 2
Marquee Hotel

Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel
4.5 star property
El Poblado
9.0 out of 10, Wonderful, (1,839 reviews)
"Nice staff, clean room , nice pool, gooood breakfast"
United States
julianus
$78 nightly
The price is $78
May 31 - Jun 1
Dann Carlton Medellin Hotel

Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo
4.0 star property
El Poblado
9.0 out of 10, Wonderful, (884 reviews)
"Excelente el hotel"
Mexico
Linette
$69 nightly
The price is $69
May 18 - May 19
Calle Flora Hotel by Jalo

Novotel Medellín El Tesoro

Novotel Medellín El Tesoro
4.5 star property
El Poblado
9.4 out of 10, Exceptional, (1,463 reviews)
"It was great place to stay, close to everything. "
United States
Carolina
$118 nightly
The price is $118
Jun 7 - Jun 8
Novotel Medellín El Tesoro

Landmark Hotel

Landmark Hotel
4.0 star property
El Poblado
9.6 out of 10, Exceptional, (365 reviews)
"Excellent stay"
United Kingdom
Richard
$85 nightly
The price is $85
Jun 14 - Jun 15
Landmark Hotel

Hotel Celestino Boutique

Hotel Celestino Boutique
3.0 star property
El Poblado
9.4 out of 10, Exceptional, (231 reviews)
"Clean rooms great massage"
United States
Patricia
$90 nightly
The price is $90
Jun 1 - Jun 2
Hotel Celestino Boutique

Medellinn The Blooming Hotel

Medellinn The Blooming Hotel
3.0 star property
El Poblado
10.0 out of 10, Exceptional, (23 reviews)
"Very new and very clean. The staff is always welcoming and helpful. Beatiful decor and just what we needed for our short stay. "
United States
Rosanna
$51 nightly
The price is $51
Jun 3 - Jun 4
Medellinn The Blooming Hotel

The Click Clack Hotel Medellin

The Click Clack Hotel Medellin
5.0 star property
El Poblado
9.2 out of 10, Wonderful, (1,136 reviews)
"Very nice hotel"
United States
Maria Luisa
$199 nightly
The price is $199
May 25 - May 26
The Click Clack Hotel Medellin

Hotel centro logistico del norte

Hotel centro logistico del norte
2.0 star property
Bello
$26 nightly
The price is $26
Jun 17 - Jun 18
Hotel centro logistico del norte

Hotel Park 10

Hotel Park 10
4.0 star property
El Poblado
9.2 out of 10, Wonderful, (1,435 reviews)
"Excellent hotel"
United States
Maria
$74 nightly
The price is $74
May 18 - May 19
Hotel Park 10

York Medellin, Curio Collection by Hilton

York Medellin, Curio Collection by Hilton
4.0 star property
El Poblado
9.6 out of 10, Exceptional, (1,158 reviews)
"Excellent hotel. "
United States
Jose Luis
$172 nightly
The price is $172
Jun 15 - Jun 16
York Medellin, Curio Collection by Hilton

Fairfield by Marriott Medellin Sabaneta

Fairfield by Marriott Medellin Sabaneta
3.5 star property
Sabaneta
9.4 out of 10, Exceptional, (265 reviews)
"Nice staff, good food, easy onsite parking and great location "
United States
Lynn
$68 nightly
The price is $68
Jun 12 - Jun 13
Fairfield by Marriott Medellin Sabaneta

Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo
4.0 star property
El Poblado
9.2 out of 10, Wonderful, (1,968 reviews)
"Breakfast was good great location clean staff very friendly and helpful "
United States
Victor Moreno
$50 nightly
The price is $50
May 25 - May 26
Hashtag 98 Hotel By Jalo

Hotel Provenza Garden

Hotel Provenza Garden
3.0 star property
El Poblado
8.6 out of 10, Excellent, (239 reviews)
"Very good location, very nice staff, totally recommended"
United States
Maria
$41 nightly
The price is $41
Jun 8 - Jun 9
Hotel Provenza Garden
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

More cheap stays in Santa Cruz

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Frequently asked questions

What is the best area to stay in Santa Cruz?
The best area to stay in Santa Cruz is the El Poblado district, particularly around Parque Lleras and the Golden Mile, as it offers a blend of upscale accommodations, dining, and entertainment options.

El Poblado is known for its tree-lined streets, modern high-rises, and a wide selection of restaurants and cafes. Parque Lleras is a central square within El Poblado where many of the area's social activities are centered, while the Golden Mile (Milla de Oro) is a stretch of avenue known for its luxury hotels, shopping centers, and corporate offices. This area provides easy access to public transportation and is well-maintained.

Couples often find El Poblado ideal due to its sophisticated dining experiences and lively evening scene. There are numerous restaurants offering various cuisines, from traditional Colombian to international dishes, and many establishments provide a pleasant ambiance for an evening out. The area's walkability also makes it convenient for exploring on foot.

For travelers seeking a convenient base with high-quality amenities, El Poblado's Golden Mile is an excellent choice. Many hotels in this section offer modern facilities, including well-equipped fitness centers and business services.
When is the best time to go to Santa Cruz?
The best time to go to Santa Cruz, Antioquia, Colombia, is during the dry season, which runs from December to February and again from June to August. These months offer the most pleasant weather for exploring the region.

During the dry season, you can expect less rainfall and more sunshine, making it ideal for outdoor activities like hiking, coffee farm tours, or simply enjoying the town's central plaza. The comfortable temperatures during these periods are particularly appealing for couples looking for a relaxed and scenic getaway.

Travelers seeking a vibrant cultural experience might also consider visiting during local festivals, which often occur outside the dry season.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Cruz.
How can I save on a Santa Cruz hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Santa Cruz hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santa Cruz hotel?
Prices for hotels in Santa Cruz often vary, but you can find a great deal from $21 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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