Beginning of main content

location Santa Cruz is highly rated for Cafes and Shopping by 103 people

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Check prices on hotels in Santa Cruz

Best deal Best deal Mar 23 - Mar 25
Tonight Tonight Feb 24 - Feb 25
This weekend This weekend Mar 2 - Mar 4
Next weekend Next weekend Mar 9 - Mar 11

Top 10 Hotels in Santa Cruz

See all 79 Hotels in Santa Cruz
Marriott Santa Cruz de la Sierra

Marriott Santa Cruz de la Sierra

4to Anillo Entre Radial 23, Santa Cruz
5.0 out of 5.0
Last booking: 2 days ago
1 others viewing this property now

Situated in Santa Cruz, this hotel is close to Ventura Mall, Santa Cruz Zoo, and Municipal Library. Also nearby are Arenal Park and Ethno-folkloric Museum.

Get Rates

Get Rates
Radisson Hotel Santa Cruz

Radisson Hotel Santa Cruz

Avenida Segunda 4, Santa Cruz
4.5 out of 5.0
Last booking: 6 hours ago

Situated in Colinas del Urubo, this hotel is 2.8 mi (4.5 km) from Santa Cruz Zoo and within 6 mi (10 km) of Guembe Biocenter and Municipal Library. Arenal Park ...

Get Rates

Get Rates
Terranova Suites

Terranova Suites

7º Anillo 400 mts al Oeste de, Santa Cruz
4.0 out of 5.0

Situated near the airport, this aparthotel is 2.9 mi (4.7 km) from Santa Cruz Zoo and within 6 mi (10 km) of Municipal Library and Arenal Park. La Recova Artisan ...

Get Rates

Get Rates
Los Tajibos Hotel And Convention Center

Los Tajibos Hotel And Convention Center

Ave. San Martin, #455, Santa Cruz
4.5 out of 5.0
Last booking: 1 day ago

Situated in Santa Cruz, this luxury hotel is within 2 mi (3 km) of Santa Cruz Zoo, Municipal Library, and Arenal Park. Ethno-folkloric Museum and Guarani Nandereko ...

Get Rates

Get Rates
Camino Real Hotel

Camino Real Hotel

Av. San Martín y 4to. Anillo, Santa Cruz
4.5 out of 5.0
Last booking: 5 hours ago
8 others viewing this property now

This family-friendly Santa Cruz hotel is located near the airport, within 3 mi (5 km) of Santa Cruz Zoo, La Recova Artisan Walk and Artecampo. Municipal Library ...

Get Rates

Get Rates
Casa Patio Hotel Boutique

Casa Patio Hotel Boutique

Av. Iberica Calle 5 #6, Santa Cruz
4.5 out of 5.0

Situated in Santa Cruz, this hotel is close to Ramon Tahuichi Aguilera Stadium, Artecampo, and Cine Center. Local attractions also include Blacutt Square and ...

Get Rates

Get Rates
Hotel LP Equipetrol

Hotel LP Equipetrol

Dr Victor Pinto, Equipetrol, Santa Cruz
4.0 out of 5.0
Last booking: 1 day ago

Situated in the entertainment district, this hotel is 0.9 mi (1.4 km) from Santa Cruz Zoo and within 3 mi (5 km) of Municipal Library and Arenal Park. Ethno-folkloric ...

Get Rates

Get Rates
Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique

Pari, 70, Santa Cruz
4.0 out of 5.0
Last booking: 5 days ago
1 others viewing this property now

Situated in Santa Cruz, this hotel is within a 10-minute walk of Sacred Art Museum, San Lorenzo Cathedral, and Franco Aleman Cultural Center. Plaza 24 de Septiembre ...

Get Rates

Get Rates
Buganvillas Hotel Suites & Spa

Buganvillas Hotel Suites & Spa

Av. Roca y Coronado No. 901, Santa Cruz
4.5 out of 5.0

This family-friendly Santa Cruz hotel is located in the business district, within 3 mi (5 km) of Guarani Nandereko Nomai Art and Culture Center, Santa Cruz Zoo ...

Get Rates

Get Rates
Hotel Cortez

Hotel Cortez

Av. Cristobal de Mendoza 280, Santa Cruz
4.0 out of 5.0

Situated in Santa Cruz, this hotel is within a 15-minute walk of Municipal Library and Arenal Park. Ethno-folkloric Museum and La Recova Artisan Walk are also ...

Get Rates

Get Rates
Map

Recent Reviews in Santa Cruz