Santa Cruz Island Vacations from $475

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The Latest Santa Cruz Island vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Cally Galapagos
Ikala Galapagos Hotel
Acacia Galapagos Boutique Hotel
Galapagos Coliving Ecuador Casa Tuna
Royal Palm Galapagos, Curio Collection Hotel by Hilton
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Discover the most popular places to visit in Santa Cruz Island

What to do in Santa Cruz Island

Santa Cruz Island Hotel Deals

Hotel Fiesta

Hotel Fiesta

3.5 out of 5
Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $155 total per night from Jan 14 to Jan 15
$155 total
Jan 14 - Jan 15
9/10 Wonderful! (386 reviews)
This is a small, friendly hotel, well maintained and a modern pool area. It is located in a quiet road just a 10 min walk from the harbour and restaurants. Breakfast was a bit limited.

Reviewed on Jan 11, 2026

Hotel Fiesta
Maidith Galapagos Inn

Maidith Galapagos Inn

3 out of 5
Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
$126 nightly
The price is $126 total per night from Jan 14 to Jan 15
$126 total
Jan 14 - Jan 15
9.8/10 Exceptional! (106 reviews)
Great place! Incredibly friendly and kind staff.

Reviewed on Jan 8, 2026

Maidith Galapagos Inn
Hotel el descanso del Guia

Hotel el descanso del Guia

3.5 out of 5
Calle Delfin, Barrio el Mirador Puerto Ayora Galapagos
$70 nightly
The price is $70 total per night from Jan 24 to Jan 25
$70 total
Jan 24 - Jan 25
8.6/10 Excellent! (183 reviews)
We are extending our stay by one day. Excellent hotel if you are prepared for the 25 minute walk to the dock Charles Darwin Ave. It is USD2 per taxi otherwise.

Reviewed on Jan 8, 2026

Hotel el descanso del Guia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Cruz Island Vacation Packages

Things to do in Santa Cruz Island

Santa Cruz Island offers an exciting blend of outdoor adventures and stunning scenery. Visitors can enjoy day trips, educational excursions, and kayak tours, as well as surf landings for some thrilling water sports. Don't miss the chance to relax at picturesque picnic spots, making the most of your vacation in this beautiful part of the Galápagos.

Shopping

Discover the vibrant Mercado de Santa Cruz, where you can find local crafts, souvenirs, and fresh produce. For a more modern experience, visit the Galería La Lobería, featuring various shops and eateries, perfect for picking up unique gifts and enjoying local cuisine.

Recreation

On Santa Cruz Island, the Galápagos Spa offers rejuvenating massages and holistic wellness treatments amidst breathtaking landscapes. Experience the serene ambiance at the Tortuga Bay Retreat, where yoga sessions and meditation classes promote relaxation and mindfulness while surrounded by nature's beauty.

Adventure

Explore the Charles Darwin Research Station to learn about conservation efforts and see giant tortoises up close. For an adrenaline rush, go snorkeling at Tortuga Bay, where you can swim alongside vibrant marine life and enjoy the stunning beach scenery.

Nightlife

The nightlife in Santa Cruz Island is vibrant and diverse. Start your evening at La Panga Restaurant for fresh seafood, then head to The Galapagos Microbrewery for local craft beers. For dancing, check out the lively atmosphere at the nightclub, where you can groove to Latin music late into the night.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Santa Cruz Island

Santa Cruz Island in the Galápagos offers an incredible adventure for outdoor enthusiasts and nature lovers. With its stunning caves, natural features, and nature reserves, visitors can explore a variety of eco-friendly attractions. Key points of interest include Santa Rosa Island and Scorpion Anchorage, making it a perfect destination for those seeking unique experiences amidst breathtaking scenery.

  • Los Gemelos Sinkholes: These impressive sinkholes, located about 4 miles from Santa Cruz Island, are a fascinating natural wonder. Formed by volcanic activity, they offer unique geological features surrounded by lush vegetation, providing an ideal spot for photography and exploration.
  • Rancho Primicias: Situated 7 miles away from Santa Cruz Island, this adventurous cave experience invites you to explore its intriguing formations. The outdoor vibes here promise excitement and a chance to connect with nature while observing the local wildlife.
  • Rancho El Manzanillo: Just 6 miles from Santa Cruz Island, this eco-friendly nature reserve is perfect for outdoor enthusiasts. With its emphasis on conservation, you can enjoy hiking trails and learn about the unique ecosystems of the Galápagos.

Best time to go to Santa Cruz Island

The best time to visit Santa Cruz Island can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santa Cruz Island falls in March, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around Santa Cruz Island falls in September, visitor numbers are slightly high and weather is mostly cloudy with no rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January76.8°F (24.9°C)No RainMostly SunnySlightly HighSlightly Low
February79.0°F (26.1°C)Light RainMostly SunnySlightly HighSlightly Low
March79.5°F (26.4°C)Light RainMostly SunnyAverageAverage
April79.0°F (26.1°C)Light RainMostly SunnyAverageAverage
May77.7°F (25.4°C)No RainMostly SunnyAverageSlightly High
June75.6°F (24.200000000000003°C)No RainMostly SunnyAverageSlightly High
July73.8°F (23.200000000000003°C)No RainMostly SunnyAverageAverage
August72.1°F (22.3°C)No RainMostly SunnyAverageSlightly High
September71.4°F (21.9°C)No RainMostly CloudySlightly HighSlightly Low
October71.8°F (22.1°C)No RainMostly SunnySlightly LowAverage
November72.7°F (22.6°C)No RainMostly SunnySlightly LowAverage
December74.7°F (23.700000000000003°C)No RainMostly SunnySlightly LowAverage

Tips to save on your trip to Santa Cruz Island

  • Combine your flights, hotels and car rentals on Expedia—bundling can result in significant savings.
  • Consider traveling during the off-peak season (typically January to February and September) for more affordable package holidays to Santa Cruz Island.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Santa Cruz Island Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Seymour Airport (GPS)

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.