Santa Cruz Tlaxcala Vacations from $330

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The Latest Santa Cruz Tlaxcala vacation packages

Price found within the past 48 hours. Click for updated prices.
Capital O Hotel Emperadores Inn, Atlixco

Capital O Hotel Emperadores Inn, Atlixco

2 out of 5
Save 100% on your flight
Price was $540, price is now $330 per person
$330
per person
Sep 1 - Sep 8
found 4 hours ago
Roundtrip flight included
Tijuana (TIJ) to Puebla (PBC)
7/10 Good! (231 reviews)
Muy buen lugar para descansar en atlixco es como una aguja en un pajar a mi parecer tiene lo necesario que uno necesita para pasarla bien y conocer la cuidad a buen costo y por la atencion muy agradable en front desk Gracias por sus atenciones

Reviewed on Jul 7, 2026

Hotel Andante

Hotel Andante

3.5 out of 5
Puebla Historic Center
Price was $979, price is now $629 per person
$629
per person
Aug 17 - Aug 24
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Puebla (PBC)
9.2/10 Wonderful! (260 reviews)
Like how well known and friendly was the staff

Reviewed on Jul 16, 2026

Casona María

Casona María

4 out of 5
Puebla Historic Center
Price was $1,024, price is now $690 per person
$690
per person
Aug 17 - Aug 24
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Puebla (PBC)
9.4/10 Exceptional! (473 reviews)
El gerente no soluciona sobre cambio de habitación además la otra habitación sin refrigeración

Reviewed on Jun 13, 2026

Xoxula by Inmense

Xoxula by Inmense

4 out of 5
Cholula
Price was $688, price is now $476 per person
$476
per person
Aug 21 - Aug 24
found 6 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to Puebla (PBC)
9/10 Wonderful! (198 reviews)
Great and friendly staff.

Reviewed on Jan 19, 2026

Grand Fiesta Americana Puebla Angelópolis

Grand Fiesta Americana Puebla Angelópolis

5 out of 5
Angelópolis
Save 100% on your flight
Price was $1,517, price is now $1,065 per person
$1,065
per person
Aug 17 - Aug 24
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Puebla (PBC)
9.6/10 Exceptional! (1,001 reviews)
Un hotel muy bonito

Reviewed on Jul 15, 2026

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Santa Cruz Tlaxcala Hotel Deals

Centro Vacacional La Trinidad

Centro Vacacional La Trinidad

2.5 out of 5
s/n Del Trabajo Santa Cruz Tlaxcala TLAX
$50 nightly
The price is $60 total per night from Jul 28 to Jul 29
$60 total
Jul 28 - Jul 29
Total with taxes and fees
6.4/10 (7 reviews)
"Overall, the property is old, the room was little bit dirty, front desk very rude, the rest were very kind."

Reviewed on Apr 28, 2026

Centro Vacacional La Trinidad
Hotel San Francisco Tlaxcala

Hotel San Francisco Tlaxcala

3.5 out of 5
Plaza de la Constitución 17 Tlaxcala TLAX
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $81 total per night from Jul 30 to Jul 31
$81 total
Jul 30 - Jul 31
Total with taxes and fees
9/10 Wonderful! (481 reviews)
"Nice breakfast"

Reviewed on Jul 18, 2026

Hotel San Francisco Tlaxcala
Holiday Inn Puebla Finsa by IHG

Holiday Inn Puebla Finsa by IHG

4 out of 5
Lateral Mexico - Puebla: 7719 Puebla PUE
Fully refundable
$70 nightly
The price is $83 total per night from Jul 19 to Jul 20
$83 total
Jul 19 - Jul 20
Total with taxes and fees
9.2/10 Wonderful! (908 reviews)
"All excellent. A very good hotel."

Reviewed on May 8, 2026

Holiday Inn Puebla Finsa by IHG
See all 257 properties in Santa Cruz Tlaxcala
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Cruz Tlaxcala Vacation Packages

Santa Cruz Tlaxcala Essential Information

Population
4,800
Top Sights
Xicotencatl National Park, Xicotencatl Theater and Government Palace

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Frequently asked questions

How much does a Santa Cruz Tlaxcala vacation package cost?
You'll find cheap prices from $330 on Expedia for your Santa Cruz Tlaxcala getaway. However, a range of factors like the hotel choice, length of stay and season will determine how much your vacation to Santa Cruz Tlaxcala costs.
What are the cheapest months to go to Santa Cruz Tlaxcala?
You're likely to find lower rates and better availability in January, May and June. Take a look at our cheap Santa Cruz Tlaxcala vacation packages and you could get some excellent off-season deals.
How many days is enough for Santa Cruz Tlaxcala?
With a well-organized itinerary, you can easily visit the main Santa Cruz Tlaxcala sights in a few days. But if you'd like to discover lesser-known spots or go on day tours, consider booking your Santa Cruz Tlaxcala vacation for longer.
How to find the best Santa Cruz Tlaxcala package deals?
Landing a cheap Santa Cruz Tlaxcala package deal is easy with Expedia. Once you've entered your destination and preferred dates under our "Packages" tab, set your budget, apply a couple of filters and see what's available. You can fine-tune your search by "Popular locations," "Property type," "Guest rating" and more. Order the results by "Price: low to high" to view the most affordable Santa Cruz Tlaxcala package deals. Want a simple trick to score even more savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are generally lower.
Is it cheaper to book a Santa Cruz Tlaxcala vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your hotel, flight and car rental into one great-value price and you could save hundreds of dollars. You'll typically score a better deal than booking each component individually. And you'll still get the flexibility to create a customized Santa Cruz Tlaxcala vacation by choosing your favorite accommodation type, airline and car class.
When to book a vacation package to Santa Cruz Tlaxcala?
If you're planning a spur-of-the-moment Santa Cruz Tlaxcala adventure, check out our last-minute deals that can be booked up to a week before you go. Prefer not to wait until the last minute? You can find terrific deals on your hotels and flights by booking ahead.
Does Expedia offer Book Now, Pay Later Santa Cruz Tlaxcala vacation packages?
Your Santa Cruz Tlaxcala break should be an escape from your daily routine, not a reason for money worries. So to give you a bit more flexibility, we've partnered with online lender Affirm to offer our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and spread the cost over 3, 6 or 12 months. Plus, there aren't any hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.