Title: Santa Cruz Vacation Rentals from $125: Search Short-Term Rentals | Expedia.com

[Santa Cruz Travel Guide](https://expedia.com/Santa-Cruz.dx553248635640644100)[Hotels in Santa Cruz](https://expedia.com/Santa-Cruz-Hotels.d553248635640644100.Travel-Guide-Hotels)[Car Rentals in Santa Cruz](https://expedia.com/Car-Rentals-In-Santa-Cruz.d553248635640644100.Car-Rental-Guide)[Santa Cruz Vacation Packages](https://expedia.com/Santa-Cruz.d553248635640644100.Destination-Travel-Guides)

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## Check prices for these dates

In two weeks

[Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=553248635640644100&startDate=2026-03-13&endDate=2026-03-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 24 - Apr 26](https://www.expedia.com/Hotel-Search?regionId=553248635640644100&startDate=2026-04-24&endDate=2026-04-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 22 - May 24](https://www.expedia.com/Hotel-Search?regionId=553248635640644100&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 19 - Jun 21](https://www.expedia.com/Hotel-Search?regionId=553248635640644100&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santa Cruz vacation rentals

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120880000/120876100/120876037/817058a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Soap, toilet paper](https://images.trvl-media.com/lodging/121000000/120880000/120876100/120876037/0c7b69ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/121000000/120880000/120876100/120876037/6cd5a3be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven](https://images.trvl-media.com/lodging/121000000/120880000/120876100/120876037/682a5b32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Heroica Nogales

[](https://www.expedia.com/Nogales-Hotels-Vrbo-Property.h120876037.Hotel-Information)

$109 nightly

$125 total

Mar 3 - Mar 4

Total with taxes and fees

[](https://www.expedia.com/Nogales-Hotels-Vrbo-Property.h120876037.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/111000000/110900000/110898200/110898176/w1288h966x1y0-7ea29fb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/111000000/110900000/110898200/110898176/b564c5a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/111000000/110900000/110898200/110898176/w1288h966x1y1-f40149d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/111000000/110900000/110898200/110898176/w1288h966x1y1-2c9a467e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Moderna Heroica Nogales

[](https://www.expedia.com/Nogales-Hotels-Beautiful-Studio-Near-Consulado.h110898176.Hotel-Information)

$126 nightly

$145 total

Mar 3 - Mar 4

Total with taxes and fees

[](https://www.expedia.com/Nogales-Hotels-Beautiful-Studio-Near-Consulado.h110898176.Hotel-Information)

![Private kitchen](https://images.trvl-media.com/lodging/112000000/111010000/111001300/111001204/3e9f90e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/112000000/111010000/111001300/111001204/2946ff12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/112000000/111010000/111001300/111001204/7a6f2828.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/112000000/111010000/111001300/111001204/f8d2e14a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Heroica Nogales

[](https://www.expedia.com/Nogales-Hotels-Vrbo-Property.h111001204.Hotel-Information)

$137 nightly

$159 total

Mar 3 - Mar 4

Total with taxes and fees

[](https://www.expedia.com/Nogales-Hotels-Vrbo-Property.h111001204.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/97000000/96040000/96039100/96039028/w906h683x59y0-4a9a4464.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/97000000/96040000/96039100/96039028/w904h683x60y0-8625dee5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96040000/96039100/96039028/w904h683x60y0-70cc5311.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/97000000/96040000/96039100/96039028/w508h683x259y0-f1247f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Heroica Nogales

[](https://www.expedia.com/Nogales-Hotels-Vrbo-Property.h96039028.Hotel-Information)

$130 nightly

$149 total

Mar 3 - Mar 4

Total with taxes and fees

[](https://www.expedia.com/Nogales-Hotels-Vrbo-Property.h96039028.Hotel-Information)

![Iron/ironing board, internet, bed sheets](https://images.trvl-media.com/lodging/125000000/124430000/124420500/124420498/9567e249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/125000000/124430000/124420500/124420498/446971cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/125000000/124430000/124420500/124420498/2beb430b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Towels, soap, toilet paper](https://images.trvl-media.com/lodging/125000000/124430000/124420500/124420498/8730a06a_edited_c939.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Heroica Nogales

[](https://www.expedia.com/Nogales-Hotels-Vrbo-Property.h124420498.Hotel-Information)

$110 nightly

$127 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Nogales-Hotels-Vrbo-Property.h124420498.Hotel-Information)

![1 bedroom, iron/ironing board, internet, bed sheets](https://images.trvl-media.com/lodging/125000000/124430000/124420200/124420110/60c413be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/125000000/124430000/124420200/124420110/5d0d660d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Towels, soap, toilet paper](https://images.trvl-media.com/lodging/125000000/124430000/124420200/124420110/200713d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Coffee and/or coffee maker](https://images.trvl-media.com/lodging/125000000/124430000/124420200/124420110/738c1e01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Heroica Nogales

[](https://www.expedia.com/Nogales-Hotels-Vrbo-Property.h124420110.Hotel-Information)

$128 nightly

$147 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Nogales-Hotels-Vrbo-Property.h124420110.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-16&endDate=2026-03-17&regionId=553248635640644100&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

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## 

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## Find vacation rentals that suit your style

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+Sonora%2C+Mexico&regionId=553248635640644100&latLong=31.192237%2C-110.54882&adults=2&startDate=2026-05-30&d1=2026-05-30&endDate=2026-06-02&d2=2026-06-02&lodging=VACATION_HOME)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+Sonora%2C+Mexico&regionId=553248635640644100&latLong=31.192237%2C-110.54882&adults=2&startDate=2026-05-30&d1=2026-05-30&endDate=2026-06-02&d2=2026-06-02&lodging=APARTMENT)

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## Top Santa Cruz Hotel Reviews

![Fiesta Inn Nogales](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145669/6a3e2d5b_y.jpg)

### Fiesta Inn Nogales

10/10 Excellent

"Yes very courteous and very clean"

[](https://expedia.com/Nogales-Hotels-Fiesta-Inn-Nogales.h1145669.Hotel-Information)

![City Express by Marriott Nogales](https://images.trvl-media.com/lodging/5000000/4330000/4326700/4326618/d58a431d_y.jpg)

### City Express by Marriott Nogales

10/10 Excellent

"Very clean "

[](https://expedia.com/Nogales-Hotels-City-Express-Nogales.h4326618.Hotel-Information)

![Fairfield Inn & Suites by Marriott Nogales](https://images.trvl-media.com/lodging/17000000/16260000/16255000/16254962/89343b5c_y.jpg)

### Fairfield Inn & Suites by Marriott Nogales

10/10 Excellent

"Great!"

[](https://expedia.com/Nogales-Hotels-Fairfield-Inn-Suites-By-Marriott-Nogales.h16254962.Hotel-Information)

![Hotel Marques De Cima](https://images.trvl-media.com/lodging/11000000/10260000/10253600/10253558/cd117355_y.jpg)

### Hotel Marques De Cima

10/10 Excellent

"Very friendly staff, clean place and excellent location."

[](https://expedia.com/Nogales-Hotels-Hotel-Marques-De-Cima.h10253558.Hotel-Information)

![Hotel Fray Marcos](https://images.trvl-media.com/lodging/8000000/7800000/7791000/7790964/cf07d2ea_y.jpg)

### Hotel Fray Marcos

10/10 Excellent

"Very clean room! Excellent service! Definitely recommend if you’re looking "

[](https://expedia.com/Nogales-Hotels-Hotel-Fray-Marcos-De-Niza.h7790964.Hotel-Information)

![City Express by Marriott Cananea](https://images.trvl-media.com/lodging/8000000/7120000/7111000/7110997/877467b2_y.jpg)

### City Express by Marriott Cananea

10/10 Excellent

"Comfortable "

[](https://expedia.com/Cananea-Hotels-City-Express-Cananea.h7110997.Hotel-Information)

![Hotel Pedregal](https://images.trvl-media.com/lodging/86000000/85780000/85771400/85771365/4df8605c_y.jpg)

### Hotel Pedregal

10/10 Excellent

"Friendly staff"

[](https://expedia.com/Nogales-Hotels-Hotel-Pedregal.h85771365.Hotel-Information)

## Find out more about Santa Cruz

**Everything you need to know about Santa Cruz vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Santa Cruz vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Cruz in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $125 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Santa Cruz rentals**

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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## Frequently asked questions

### Are there vacation rentals in Santa Cruz?

### What are some of the best vacation rentals in Santa Cruz?

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### What are vacation rentals like in Santa Cruz?

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