---
title: "Top 10 Hotels in Santa Fe, FL (from $72) 2026 - Competitive Prices | Expedia"
description: "Find 623 of the best hotels in Santa Fe, FL in 2026. Compare room rates, hotel reviews and availability. Most hotels are fully refundable."
canonical: "https://www.expedia.com/Santa-Fe-Hotels.d553248635975870004.Travel-Guide-Hotels"
language: en-US
market: US
currency: USD
prices_as_of: 2026-11-12T18:47:57Z
---

Plan your trip

- [Santa Fe Travel Guide](https://www.expedia.com/Santa-Fe.dx553248635975870004)
- [Flights to Santa Fe](https://www.expedia.com/Cheap-Flights-To-Santa-Fe.d553248635975870004.Travel-Guide-Flights)
- [Car Rentals in Santa Fe](https://www.expedia.com/Car-Rentals-In-Santa-Fe.d553248635975870004.Car-Rental-Guide)
- [Santa Fe Vacation Packages](https://www.expedia.com/Santa-Fe.d553248635975870004.Destination-Travel-Guides)
- [Vacation Rentals in Santa Fe](https://www.expedia.com/Santa-Fe-Vacation-Rentals.d553248635975870004.Travel-Guide-VacationRentals)

# Find hotels in Santa Fe, FL from $72

### Upfront pricing
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## Go beyond your typical stay in Santa Fe

[Pet friendly](https://www.expedia.com/Hotel-Search?destination=Santa%20Fe,%20Florida,%20United%20States%20of%20America&regionId=553248635975870004&latLong=29.883575,-82.430391&adults=2&startDate=2026-11-19&d1=2026-11-19&endDate=2026-11-21&d2=2026-11-21&amenities=PETS)

[Pool](https://www.expedia.com/Hotel-Search?destination=Santa%20Fe,%20Florida,%20United%20States%20of%20America&regionId=553248635975870004&latLong=29.883575,-82.430391&adults=2&startDate=2026-11-19&d1=2026-11-19&endDate=2026-11-21&d2=2026-11-21&amenities=POOL)

[Hot tub](https://www.expedia.com/Hotel-Search?destination=Santa%20Fe,%20Florida,%20United%20States%20of%20America&regionId=553248635975870004&latLong=29.883575,-82.430391&adults=2&startDate=2026-11-19&d1=2026-11-19&endDate=2026-11-21&d2=2026-11-21&amenities=HOT%5FTUB)

[Cabin](https://www.expedia.com/Hotel-Search?destination=Santa%20Fe,%20Florida,%20United%20States%20of%20America&regionId=553248635975870004&latLong=29.883575,-82.430391&adults=2&startDate=2026-11-19&d1=2026-11-19&endDate=2026-11-21&d2=2026-11-21&lodging=CABIN)

[Apart­ment](https://www.expedia.com/Hotel-Search?destination=Santa%20Fe,%20Florida,%20United%20States%20of%20America&regionId=553248635975870004&latLong=29.883575,-82.430391&adults=2&startDate=2026-11-19&d1=2026-11-19&endDate=2026-11-21&d2=2026-11-21&lodging=APARTMENT)

[Family friendly](https://www.expedia.com/Hotel-Search?destination=Santa%20Fe,%20Florida,%20United%20States%20of%20America&regionId=553248635975870004&latLong=29.883575,-82.430391&adults=2&startDate=2026-11-19&d1=2026-11-19&endDate=2026-11-21&d2=2026-11-21&travelerType=family%5Ffriendly)

[Condo](https://www.expedia.com/Hotel-Search?destination=Santa%20Fe,%20Florida,%20United%20States%20of%20America&regionId=553248635975870004&latLong=29.883575,-82.430391&adults=2&startDate=2026-11-19&d1=2026-11-19&endDate=2026-11-21&d2=2026-11-21&lodging=CONDO)

[Cottage](https://www.expedia.com/Hotel-Search?destination=Santa%20Fe,%20Florida,%20United%20States%20of%20America&regionId=553248635975870004&latLong=29.883575,-82.430391&adults=2&startDate=2026-11-19&d1=2026-11-19&endDate=2026-11-21&d2=2026-11-21&lodging=COTTAGE)

[Waterpark](https://www.expedia.com/Hotel-Search?destination=Santa%20Fe,%20Florida,%20United%20States%20of%20America&regionId=553248635975870004&latLong=29.883575,-82.430391&adults=2&startDate=2026-11-19&d1=2026-11-19&endDate=2026-11-21&d2=2026-11-21&amenities=WATER%5FPARK)

[Campsite](https://www.expedia.com/Hotel-Search?destination=Santa%20Fe,%20Florida,%20United%20States%20of%20America&regionId=553248635975870004&latLong=29.883575,-82.430391&adults=2&startDate=2026-11-19&d1=2026-11-19&endDate=2026-11-21&d2=2026-11-21&lodging=CARAVAN%5FPARK)

## Check prices for these dates

[Check prices for these dates, December 12 – 13, 2026](https://www.expedia.com/Hotel-Search?regionId=553248635975870004&startDate=2026-12-12&endDate=2026-12-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

[View in a map](https://www.expedia.com/Hotel-Search?regionId=553248635975870004&stayLength=1&daysInFuture=30&pwaOverlay=map)

## Our top choices for Santa Fe hotels

### [1\. Hampton Inn & Suites Alachua I-75](https://www.expedia.com/Gainesville-Hotels-Hampton-Inn-Suites-Alachua-I-75.h64474824.Hotel-Information)

![A modern kitchen area with a central counter, various food stations, and a chalkboard menu.](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/1d4a6615.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

- Location: Alachua
- Guest rating: 9.4/10 (Exceptional, 572 reviews)
- Price: $114 nightly, $128 total, Nov 29 - Nov 30, Total with taxes and fees
- Review: Great breakfast!, by Pamela

### [2\. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG](https://www.expedia.com/Gainesville-Hotels-Holiday-Inn-Express-Suites-Alachua-Gainesville-Area.h22858269.Hotel-Information)

![A hotel with a covered entrance, stone facade, and blue lighting accents.](https://images.trvl-media.com/lodging/23000000/22860000/22858300/22858269/f20d3b23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Alachua
- Guest rating: 9.4/10 (Exceptional, 1001 reviews)
- Price: $110 nightly, $124 total, Nov 29 - Nov 30, Total with taxes and fees
- Review: Great stay!!, by Austin

### [3\. Best Western Gateway Grand](https://www.expedia.com/Gainesville-Hotels-Best-Western-Gateway-Grand.h151041.Hotel-Information)

![A large, multi-story hotel with a central courtyard, palm trees, and an American flag.](https://images.trvl-media.com/lodging/1000000/160000/151100/151041/9a241e09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Gainesville
- Guest rating: 8.6/10 (Excellent, 1528 reviews)
- Price: $85 nightly, $95 total, Nov 19 - Nov 20, Total with taxes and fees
- Review: The hotel was great! Friendly staff and the breakfast was amazing., by Jvotric

### [4\. La Quinta by Wyndham Gainesville](https://www.expedia.com/Gainesville-Hotels-La-Quinta-By-Wyndham-Gainesville.h37760006.Hotel-Information)

![A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a well-maintained outdoor area with a parking lot.](https://images.trvl-media.com/lodging/38000000/37770000/37760100/37760006/d9964af7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Gainesville
- Guest rating: 9.2/10 (Wonderful, 1389 reviews)
- Price: $97 nightly, $109 total, Nov 15 - Nov 16, Total with taxes and fees
- Review: Great stay while in town for a baseball tournament., by Megan

### [5\. Clarion Pointe Alachua - Gainesville Area](https://www.expedia.com/Gainesville-Hotels-Travelodge-By-Wyndham-Alachua.h7326.Hotel-Information)

![A modern hotel room with a large bed, a flat-screen TV, a desk, and a mural of a landscape.](https://images.trvl-media.com/lodging/1000000/10000/7400/7326/3d2775a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Alachua
- Guest rating: 8/10 (Very good, 29 reviews)
- Price: $72 nightly, $81 total, Dec 3 - Dec 4, Total with taxes and fees
- Review: Big beautiful pool, room was very clean, bed was super comfortable, staff was awesome!, by Debra

### [6\. Quality Inn Alachua - Gainesville Area](https://www.expedia.com/Gainesville-Hotels-Quality-Inn-I-75-At-Exit-399.h898728.Hotel-Information)

![A cozy restaurant with wooden beams, yellow walls, and a bar area with coffee machines.](https://images.trvl-media.com/lodging/1000000/900000/898800/898728/3c5f8667.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Alachua
- Guest rating: 7.2/10 (Good, 1009 reviews)
- Price: $72 nightly, $81 total, Nov 22 - Nov 23, Total with taxes and fees
- Review: Very convenient location, by faye

### [7\. Sleep Inn & Suites University/Shands](https://www.expedia.com/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information)

![A hotel room with a bed, bedside tables, a TV, a window with curtains, and a wall with artwork.](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/2124ab08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Gainesville
- Guest rating: 8.8/10 (Excellent, 1332 reviews)
- Price: $81 nightly, $91 total, Dec 4 - Dec 5, Total with taxes and fees
- Review: The hotel is nice, the staff was friendly, great location and the room was very clean, by Rose

### [8\. BlueGem Motel](https://www.expedia.com/High-Springs-Hotels-BlueGem-Motel.h87671816.Hotel-Information)

![A stone water feature with cascading water, surrounded by a brick wall and greenery.](https://images.trvl-media.com/lodging/88000000/87680000/87671900/87671816/dffd0064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: High Springs
- Guest rating: 9.2/10 (Wonderful, 488 reviews)
- Price: $96 nightly, $108 total, Nov 16 - Nov 17, Total with taxes and fees
- Review: Very clean rooms and homey atmosphere!, by Myra

### [9\. Palms Garden Inn](https://www.expedia.com/Lake-City-Hotels-Palms-Garden-Inn.h40753.Hotel-Information)

![A hotel room with a bed, a desk, a chair, a refrigerator, and a microwave.](https://images.trvl-media.com/lodging/1000000/50000/40800/40753/51a782f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Lake City
- Guest rating: 7.6/10 (Good, 665 reviews)
- Price: $65 nightly, $73 total, Dec 13 - Dec 14, Total with taxes and fees
- Review: great family frindley inn. great rates.3 foods close to inn.walking distance to, by Ron

### [10\. Aloft by Marriott Gainesville University Area](https://www.expedia.com/Gainesville-Hotels-Aloft-Gainesville-University-Area.h23829675.Hotel-Information)

![A modern hotel with a flat roof, multiple floors, and a prominent 'aloft' sign.](https://images.trvl-media.com/lodging/24000000/23830000/23829700/23829675/2c077c5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Gainesville
- Guest rating: 8.8/10 (Excellent, 1000 reviews)
- Price: $87 nightly, $98 total, Nov 15 - Nov 16, Total with taxes and fees
- Review: Nice place, by Esteban

### [11\. Hotel Indigo Gainesville-Celebration Pointe by IHG](https://www.expedia.com/Gainesville-Hotels-Hotel-Indigo-Gainesville-Celebration-Pointe.h26940780.Hotel-Information)

![An outdoor seating area with a fire feature, chairs, and tables.](https://images.trvl-media.com/lodging/27000000/26950000/26940800/26940780/fc66f4ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Gainesville
- Guest rating: 9.2/10 (Wonderful, 1062 reviews)
- Price: $102 nightly, $115 total, Nov 22 - Nov 23, Total with taxes and fees
- Review: Very clean and nice hotel! Stayed with our 2 kids and felt very safe to stay there, by Dalton

### [12\. Holiday Inn Express Starke by IHG](https://www.expedia.com/Starke-Hotels-Holiday-Inn-Express-Starke.h90143200.Hotel-Information)

![A modern breakfast area with labeled dispensers for yogurt, eggs, and milk, a coffee machine, and a chalkboard menu.](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/baab3408.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Starke
- Guest rating: 9.6/10 (Exceptional, 652 reviews)
- Price: $101 nightly, $112 total, Nov 22 - Nov 23, Total with taxes and fees
- Review: Very clean rooms and wonderful staff., by Georgia

### [13\. Best Western Waldo Inn and Suites](https://www.expedia.com/Gainesville-Hotels-Best-Western-Waldo-Inn-And-Suites.h2384393.Hotel-Information)

![A hotel room with a bed, a sofa, a coffee table, and a small table with a lamp.](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/894b95a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Waldo
- Guest rating: 8.8/10 (Excellent, 1000 reviews)
- Price: $84 nightly, $95 total, Nov 22 - Nov 23, Total with taxes and fees
- Review: Close to downtown St Augustine - about 15 mins away, by Sarah

### [14\. Hampton Inn & Suites Gainesville Downtown University](https://www.expedia.com/Gainesville-Hotels-Hampton-Inn-Suites-Gainesville-Downtown.h2873991.Hotel-Information)

![A hotel lobby with a seating area, a sofa, a table, and a lamp.](https://images.trvl-media.com/lodging/3000000/2880000/2874000/2873991/aac3d418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Downtown Gainesville
- Guest rating: 8.6/10 (Excellent, 1000 reviews)
- Price: $91 nightly, $102 total, Nov 27 - Nov 28, Total with taxes and fees
- Review: Nice hotel, loved the location, by Graziella

### [15\. Drury Inn & Suites Gainesville](https://www.expedia.com/Gainesville-Hotels-Drury-Inn-Suites-Gainesville.h19484503.Hotel-Information)

![A spacious lobby with a sectional sofa, a wooden cabinet, and a television mounted on the wall.](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/0dff4e4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Gainesville
- Guest rating: 9.6/10 (Exceptional, 1681 reviews)
- Price: $105 nightly, $118 total, Nov 26 - Nov 27, Total with taxes and fees
- Review: Hotel was immaculate-Staff extremely friendly and Meals included were great, by Michael

### [16\. Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy](https://www.expedia.com/Postcard-Cabins-Gilchrist-Springs.h110494372.Hotel-Information)

![A cabin with a cozy interior, a dining area, and a view of the forest.](https://images.trvl-media.com/lodging/111000000/110500000/110494400/110494372/b6422f76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: High Springs
- Guest rating: 10/10 (Exceptional, 299 reviews)
- Price: $207 nightly, $228 total, Dec 13 - Dec 14, Total with taxes and fees
- Review: Great place to stay for checking out the springs in the area, by Katie

### [17\. Royal Inn](https://www.expedia.com/Gainesville-Hotels-Royal-Inn.h11843348.Hotel-Information)

![A hotel room with two beds, a desk, a chair, and a television.](https://images.trvl-media.com/lodging/12000000/11850000/11843400/11843348/547e560b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Alachua
- Guest rating: 7.2/10 (Good, 208 reviews)
- Price: $70 nightly, $79 total, Nov 13 - Nov 14, Total with taxes and fees
- Review: Bugs in room, by James

### [18\. Hyatt Place Gainesville Downtown](https://www.expedia.com/Gainesville-Hotels-Hyatt-Place-Gainesville-Downtown.h78547624.Hotel-Information)

![A modern interior with a staircase, a seating area, and a colorful abstract wall design.](https://images.trvl-media.com/lodging/79000000/78550000/78547700/78547624/0d00e88d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Downtown Gainesville
- Guest rating: 9.2/10 (Wonderful, 1250 reviews)
- Price: $104 nightly, $116 total, Nov 16 - Nov 17, Total with taxes and fees
- Review: Excelent Hotel!, by Misak

### [19\. TownePlace Suites by Marriott Gainesville Northwest](https://www.expedia.com/Gainesville-Hotels-TownePlace-Suites-By-Marriott-Gainesville-Northwest.h9312530.Hotel-Information)

![An outdoor patio with wicker furniture, stone walls, and a barbecue grill.](https://images.trvl-media.com/lodging/10000000/9320000/9312600/9312530/2f2266c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Gainesville
- Guest rating: 8.4/10 (Very good, 791 reviews)
- Price: $105 nightly, $118 total, Nov 15 - Nov 16, Total with taxes and fees
- Review: Breakfast can do better., by Jell

### [20\. Country Inn & Suites by Radisson, Gainesville, FL](https://www.expedia.com/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information)

![A multi-story hotel with a central entrance, palm trees, and a clear sky.](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/e387508a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Gainesville
- Guest rating: 9.2/10 (Wonderful, 2030 reviews)
- Price: $88 nightly, $99 total, Nov 22 - Nov 23, Total with taxes and fees
- Review: We had a wonderful stay. The hotel was great and the staff was even better!!, by Jeff

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://www.expedia.com/Hotel-Search?startDate=2026-11-26&endDate=2026-11-27&regionId=553248635975870004&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Top Santa Fe Hotel Reviews

### [Hampton Inn & Suites Alachua I-75](https://www.expedia.com/Gainesville-Hotels-Hampton-Inn-Suites-Alachua-I-75.h64474824.Hotel-Information)

![A modern kitchen area with a central counter, various food stations, and a chalkboard menu.](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/1d4a6615.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 15930 Northwest 163rd Lane, Alachua, FL, 32615, US
- Location: Alachua
- Star rating: 2.5/5
- Guest rating: 9.4/10 (572 reviews)
- Review: This is my go-to hotel when I visit the springs. The rooms are comfortable and great. Thanks, by Jose, May 29, 2024, rated 10/10 Excellent

### [La Quinta by Wyndham Gainesville](https://www.expedia.com/Gainesville-Hotels-La-Quinta-By-Wyndham-Gainesville.h37760006.Hotel-Information)

![A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a well-maintained outdoor area with a parking lot.](https://images.trvl-media.com/lodging/38000000/37770000/37760100/37760006/d9964af7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 908 NW 69 Terrace, Gainesville, FL, 32605, US
- Location: Gainesville
- Star rating: 3/5
- Guest rating: 9.2/10 (1389 reviews)
- Review: The hotel appears to be new. It's very clean and we heard no noise. The only thing that wasn't excellent was the breakfast. It was good, just not great. Will definitely stay there again., by Alan, March 19, 2024, rated 10/10 Excellent

### [Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy](https://www.expedia.com/Postcard-Cabins-Gilchrist-Springs.h110494372.Hotel-Information)

![A cabin with a cozy interior, a dining area, and a view of the forest.](https://images.trvl-media.com/lodging/111000000/110500000/110494400/110494372/b6422f76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 1699 NE Co Rd 337, High Springs, FL, 32643, US
- Location: High Springs
- Star rating: 2/5
- Guest rating: 10/10 (299 reviews)
- Review: Awesome , nice experience in the middle of the forest and 15 minutes away from ginnie springs, by Alexander, July 22, 2025, rated 10/10 Excellent

### [Holiday Inn Express Starke by IHG](https://www.expedia.com/Starke-Hotels-Holiday-Inn-Express-Starke.h90143200.Hotel-Information)

![A modern breakfast area with labeled dispensers for yogurt, eggs, and milk, a coffee machine, and a chalkboard menu.](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/baab3408.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 15111 S.Highway 301, Starke, FL, 32091, US
- Location: Starke
- Star rating: 2.5/5
- Guest rating: 9.6/10 (652 reviews)
- Review: N/A, by Andrea, November 11, 2026, rated 10/10 Excellent

### [Drury Inn & Suites Gainesville](https://www.expedia.com/Gainesville-Hotels-Drury-Inn-Suites-Gainesville.h19484503.Hotel-Information)

![A spacious lobby with a sectional sofa, a wooden cabinet, and a television mounted on the wall.](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/0dff4e4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 4000 Southwest 40th Blvd, Gainesville, FL, 32608, US
- Location: Gainesville
- Star rating: 3/5
- Guest rating: 9.6/10 (1681 reviews)
- Review: The stay was family friendly and very comfortable. Very spacious and clean rooms. The pool is very large and the hot tub was hot. The food was great and staff are very friendly and responsive., by Jennifer, May 18, 2025, rated 10/10 Excellent

### [Best Western Gateway Grand](https://www.expedia.com/Gainesville-Hotels-Best-Western-Gateway-Grand.h151041.Hotel-Information)

![A large, multi-story hotel with a central courtyard, palm trees, and an American flag.](https://images.trvl-media.com/lodging/1000000/160000/151100/151041/9a241e09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 4200 NW 97th Blvd, Gainesville, FL, 32606, US
- Location: Gainesville
- Star rating: 3/5
- Guest rating: 8.6/10 (1528 reviews)
- Review: I enjoyed the free breakfast, the hot tub, and the staff. Everyone was friendly and helpful, by jennifer Louise, April 7, 2025, rated 10/10 Excellent

### [Hyatt Place Gainesville Downtown](https://www.expedia.com/Gainesville-Hotels-Hyatt-Place-Gainesville-Downtown.h78547624.Hotel-Information)

![A modern interior with a staircase, a seating area, and a colorful abstract wall design.](https://images.trvl-media.com/lodging/79000000/78550000/78547700/78547624/0d00e88d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 212 SE 1ST STREET,, Gainesville, FL, 32601, US
- Location: Downtown Gainesville
- Star rating: 3/5
- Guest rating: 9.2/10 (1250 reviews)
- Review: Highly recommend!, by Brandon, September 10, 2024, rated 10/10 Excellent

### [Fairfield Inn & Suites by Marriott Gainesville I-75](https://www.expedia.com/Gainesville-Hotels-Fairfield-Inn-Suites-By-Marriott-Gainesville-I-75.h19949875.Hotel-Information)

![A modern bar area with a long counter, green bar stools, and a television displaying a golf game.](https://images.trvl-media.com/lodging/20000000/19950000/19949900/19949875/f7744ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Gainesville
- Review: Room was clean and quiet. Food was good service was excellent., by Marita, June 1, 2021, rated 10/10 Excellent

### [Sweetwater Branch Inn](https://www.expedia.com/Gainesville-Hotels-Sweetwater-Branch-Inn.h1201421.Hotel-Information)

![A large, two-story house with a porch, multiple windows, and a chimney.](https://images.trvl-media.com/lodging/2000000/1210000/1201500/1201421/c2f8fb6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Gainesville
- Review: I had a mini vacation here between conferences at the University of Florida. I had a delightful room, wonderful facilities, gardens, saltwater pool, and the cat Butterscotch was a wonderful friend as I had a lovely evening in a rocker on the porch with a bit of wine and a book. I highly recommend the massage therapist option. She was wonderful and set up and collapse was not intrusive in my room., by Carol, July 21, 2016, rated 10/10 Excellent

### [Hotel Indigo Gainesville-Celebration Pointe by IHG](https://www.expedia.com/Gainesville-Hotels-Hotel-Indigo-Gainesville-Celebration-Pointe.h26940780.Hotel-Information)

![An outdoor seating area with a fire feature, chairs, and tables.](https://images.trvl-media.com/lodging/27000000/26950000/26940800/26940780/fc66f4ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 5020 SW 30th Lane, Gainesville, FL, 32608, US
- Location: Gainesville
- Star rating: 3.5/5
- Guest rating: 9.2/10 (1062 reviews)
- Review: Hotel was very unique, easy easy parking clean, by Katrina, September 11, 2024, rated 10/10 Excellent

### [Comfort Suites Gainesville near University](https://www.expedia.com/Gainesville-Hotels-Comfort-Suites-Gainesville-Near-University.h54138132.Hotel-Information)

![A modern living room with a fireplace, comfortable seating, a flat-screen TV, and a large window.](https://images.trvl-media.com/lodging/55000000/54140000/54138200/54138132/95cd6e6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Gainesville
- Review: My daughter & I stay here frequently as it’s conveniently located near the medical facility UF Health. They apparently put great effort in keeping the facility clean. A lot of fact that it’s just shy of all the hustle and bustle of Gainesville, but within minutes of the University and the Hospital, the staff has accommodated me when I’ve asked for special needs, and I will always return to this this hotel., by Elizabeth, November 10, 2026, rated 10/10 Excellent

### [Vista Verde Farm Retreat](https://www.expedia.com/Lake-City-Hotels-Vista-Verde-Farm-Retreat.h112641197.Hotel-Information)

![A modern kitchen with a flat-screen TV, a microwave, and a coffee maker on a wooden cabinet. There is a window with a view of a green landscape.](https://images.trvl-media.com/lodging/113000000/112650000/112641200/112641197/0b12a87b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Lake City
- Review: What a wonderful option instead of staying in a hotel. Overall, it was fantastic and we had a wonderful time!, by Steven, September 30, 2026, rated 10/10 Excellent

### [BlueGem Motel](https://www.expedia.com/High-Springs-Hotels-BlueGem-Motel.h87671816.Hotel-Information)

![A stone water feature with cascading water, surrounded by a brick wall and greenery.](https://images.trvl-media.com/lodging/88000000/87680000/87671900/87671816/dffd0064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 19544 NW US Hwy 441, High Springs, FL, 32643, US
- Location: High Springs
- Star rating: 2/5
- Guest rating: 9.2/10 (488 reviews)
- Review: Very clean with comfortable beds and nice bedding. Good size room. Small bathroom., by Tina, October 26, 2024, rated 10/10 Excellent

### [Sleep Inn & Suites University/Shands](https://www.expedia.com/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information)

![A hotel room with a bed, bedside tables, a TV, a window with curtains, and a wall with artwork.](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/2124ab08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 4110 SW 40th Boulevard, Gainesville, FL, 32608, US
- Location: Gainesville
- Star rating: 2.5/5
- Guest rating: 8.8/10 (1332 reviews)
- Review: Come to Gainesville often… just have a procedure early, by Lisa, April 24, 2024, rated 10/10 Excellent

### [Country Inn & Suites by Radisson, Gainesville, FL](https://www.expedia.com/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information)

![A multi-story hotel with a central entrance, palm trees, and a clear sky.](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/e387508a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 4015 Sw 43rd St, Gainesville, FL, 32608, US
- Location: Gainesville
- Star rating: 3/5
- Guest rating: 9.2/10 (2030 reviews)
- Review: I love this hotel....it have a very good customer service, and they take care of all needs . very friendly personal..great beads and nice rooms.. i always go back whem im at Gainsville, by Georgette, April 30, 2025, rated 10/10 Excellent

### [Aloft by Marriott Gainesville University Area](https://www.expedia.com/Gainesville-Hotels-Aloft-Gainesville-University-Area.h23829675.Hotel-Information)

![A modern hotel with a flat roof, multiple floors, and a prominent 'aloft' sign.](https://images.trvl-media.com/lodging/24000000/23830000/23829700/23829675/2c077c5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 3743 Hull Rd, Gainesville, FL, 32607, US
- Location: Gainesville
- Star rating: 3/5
- Guest rating: 8.8/10 (1000 reviews)
- Review: Excelente place and quiet area. Very nice staff and comfort bed., by Luis, August 18, 2020, rated 10/10 Excellent

### [Hampton Inn & Suites Gainesville Downtown University](https://www.expedia.com/Gainesville-Hotels-Hampton-Inn-Suites-Gainesville-Downtown.h2873991.Hotel-Information)

![A hotel lobby with a seating area, a sofa, a table, and a lamp.](https://images.trvl-media.com/lodging/3000000/2880000/2874000/2873991/aac3d418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 101 SE 1st Ave, Gainesville, FL, 32601, US
- Location: Downtown Gainesville
- Star rating: 3/5
- Guest rating: 8.6/10 (1000 reviews)
- Review: The people that worked there were awesome we were happy!, by Anonymous traveler, September 12, 2020, rated 10/10 Excellent

### [Depot Village](https://www.expedia.com/Gainesville-Hotels-Depot-Village.h92535326.Hotel-Information)

![A modern kitchen with a wooden ceiling, a built-in island, and a dining area with a table and chairs.](https://images.trvl-media.com/lodging/93000000/92540000/92535400/92535326/0d3fef73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Gainesville
- Review: Everything was great, perfect location, by Stephen, November 10, 2026, rated 10/10 Excellent

## Frequently Asked Questions

### What are some of the best vacation rentals in Santa Fe?

[ 5BR UF Family Retreat with Private Pool, Pond, Game Room – Sleeps 10](https://www.expedia.com/Gainesville-Hotels-The-Pond-House-Large-Pool.h99662817.Hotel-Information): This vacation home rental outside of Santa Fe is located on a lake and has an outdoor pool, a fireplace, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a patio, a garden, and a selection of games so you can immerse yourself in your vacation. See all [vacation rentals in Santa Fe](https://www.expedia.com/Santa-Fe-Vacation-Rentals.d553248635975870004.Travel-Guide-VacationRentals).

### If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?

Yes, most hotel bookings are fully refundable if cancelled before the hotel’s cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Filter your search by [fully refundable](https://www.expedia.com/Hotel-Search?regionId=553248635975870004&paymentType=FREE%5FCANCELLATION) to find flexible hotel deals in Santa Fe.

### Where can I learn more about changing or cancelling my trip to Santa Fe?

To access more information about picking new dates or cancelling your trip to Santa Fe, go to <https://www.expedia.com/service/>.

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- [Visit Northern Florida](https://www.expedia.com/Northern-Florida.dx6233767)
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- [Things to do in Gainesville](https://www.expedia.com/Things-To-Do-In-Gainesville.d6048189.Travel-Guide-Activities)
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