Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Check prices on hotels in Santa Fe

Tonight Tonight Jun 24 - Jun 25
This weekend This weekend Jun 29 - Jul 1
Next weekend Next weekend Jul 6 - Jul 8

Featured Santa Fe Business Hotels

See all 645 Properties in Santa Fe
Camino Real Santa Fe

Camino Real Santa Fe

Guillermo Gonzalez Camarena 300, Mexico City
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
3.9 out of 5 (967 reviews)
Nice hotel, good location, great breakfastWe had a great experience in the hotel. They have a small bar in floor 14 where you can have a couple of drinks with a nice view of the city. The room is clean, comfortable and with nice dimensions, I stayed with my brother and sister in the same room and didn't feel crowded. The curtains are very ...
Dec 11, 2017
The Westin Santa Fe, Mexico City

The Westin Santa Fe, Mexico City

Javier Barros Sierra 540, Mexico City
  • Free Cancellation
  • Reserve now, pay when you stay
4.5 out of 5.0
 
 
4.6 out of 5 (262 reviews)
I will stay there againAmazing!!!!
Jan 20, 2018
Intercontinental Presidente Santa Fe Mexico

Intercontinental Presidente Santa Fe Mexico

Juan Salvador Agraz 97, Ave Real, Mexico City
    4.0 out of 5.0
     
     
    4.5 out of 5 (454 reviews)
    Santa Fe.Excellent view, and best service.
    Mar 23, 2018
    NH Collection Mexico City Santa Fé

    NH Collection Mexico City Santa Fé

    Juan Salvador Agraz, 44, Mexico City
    • Free Cancellation
    • Reserve now, pay when you stay
    4.0 out of 5.0
     
     
    4.2 out of 5 (313 reviews)
    Great customer service and locationI really enjoyed my stay there and would definitely recommend it to friends and family.
    Mar 3, 2018

    NH Collection Mexico City Santa Fé$60

    NH Collection Mexico City Santa Fé$60
    Hilton Mexico City Santa Fe

    Hilton Mexico City Santa Fe

    Antonio Dovali Jaime No. 70, Mexico City
    • Free Cancellation
    • Reserve now, pay when you stay
    4.5 out of 5.0
     
     
    4.6 out of 5 (366 reviews)
    Lovely Absolutely loved it there, staff was so nice everybody accommodated us. Everyone spoke English excellently, overall just impressed, seem as everyone cared about our needs. Everyone was really helpful especially Jonathan. Thank you all for your exceptional hospitality.
    Mar 27, 2018
    JW Marriott Hotel Mexico City Santa Fe

    JW Marriott Hotel Mexico City Santa Fe

    Ave Sante Fe 160 Col Santa F, Mexico City
    • Free Cancellation
    • Reserve now, pay when you stay
    4.5 out of 5.0
     
     
    4.5 out of 5 (133 reviews)
    Great locationPerfectly located near restaurants and shopping. Walking distance.
    Mar 11, 2018
    Holiday Inn México Santa Fe

    Holiday Inn México Santa Fe

    Guillermo Gonzalez Camarena, Mexico City
    • Free Cancellation
    • Reserve now, pay when you stay
    3.0 out of 5.0
     
     
    4.4 out of 5 (80 reviews)
    Nice eats, walkableGoog hotel, easy check in and out. Area surrounding is pleasant. Big shopping just 15 min walk as well.
    Mar 2, 2018
    Hotel Novotel Mexico City Santa Fe

    Hotel Novotel Mexico City Santa Fe

    Antonio Dovali Jaime 75, Mexico City
    • Free Cancellation
    • Reserve now, pay when you stay
    3.0 out of 5.0
     
     
    4.1 out of 5 (333 reviews)
    Great for work in Santa FeThe room was clean and comfortable with a great shower. If you are coming for business in Santa Fe, this is a great location at a great price! It was a bit harder to find a quiet corner in the lobby or breakfast area to work. Still, overall a great experience and I will stay there again.
    Mar 5, 2018
    Comfort Inn Ciudad de Mexico Santa Fe

    Comfort Inn Ciudad de Mexico Santa Fe

    Prol. Paseo de la Reforma 557, Mexico City
    • Free Cancellation
    • Reserve now, pay when you stay
    3.5 out of 5.0
     
     
    3.7 out of 5 (565 reviews)
    Good hotel for Business TripIt was very comfortable and well located.
    Mar 2, 2018
    Hotel Aspen

    Hotel Aspen

    Av. Vasco de Quiroga #1840, Mexico City
      3.5 out of 5.0
       
       
      3.9 out of 5 (79 reviews)
      Make it a bit more family friendly.The elevator doors closes too soon and several times they closed on us, even in our 2 year old daughter and hit her face... they need to fix this. Also, we made the reservation for 2 adults and one small child, however we only had towels for 2 people. Wifi stopped working the first night until the ...
      Feb 26, 2018
      DoubleTree by Hilton Hotel Mexico City Santa Fe

      DoubleTree by Hilton Hotel Mexico City Santa Fe

      Calle 3 No. 55 Col. Lomas de Santa Fe, Mexico City
      • Free Cancellation
      • Reserve now, pay when you stay
      3.5 out of 5.0
       
       
      4.2 out of 5 (339 reviews)
      Conveniently LocatedExcellent location. Close to all major Corporate Headquarters
      Jan 25, 2018
      Sheraton Santa Fe, Mexico City

      Sheraton Santa Fe, Mexico City

      Calle Guillermo González Camarena # 200, Mexico City
      • Free Cancellation
      • Reserve now, pay when you stay
      4.0 out of 5.0
       
       
      4.5 out of 5 (153 reviews)
      Mexico City Sheraton HotelWe arrived weary travellers with our small dog Lulu the Magnifica. We were welcomed and taken care of immediately . To our surprise they brought a lovely dog bed , a dog mat that fitted over the bowls that they provided for Lulu . Bravo Sheraton México
      Apr 20, 2018
      City Express Suites Santa Fe

      City Express Suites Santa Fe

      Juan Salvador Agraz, 69, Mexico City
      • Free Cancellation
      • Reserve now, pay when you stay
      2.5 out of 5.0
       
       
      3.8 out of 5 (77 reviews)
      Nivel hotel right on the Santa Fe bussinessThe hotel room was very Nice, have a small living room with tv, Also kitchen, two different rooms with beds TV and bathroom . The bathroom has some hairs in the shower. The breakfast was Also Ok.
      Mar 18, 2017

      City Express Suites Santa Fe$69

      City Express Suites Santa Fe$69
      City Express Plus Santa Fe

      City Express Plus Santa Fe

      Juan Salvador Agraz No. 69, Mexico City
      • Free Cancellation
      • Reserve now, pay when you stay
      3.0 out of 5.0
       
       
      4.0 out of 5 (482 reviews)
      Nice stayNice stay at City Express Plus Santa Fe. Second night they did not leave towels and staff did not provide receipt for dinner on Thursday night from room service. Other than that it was excellent
      Jun 16, 2018

      City Express Plus Santa Fe$51

      City Express Plus Santa Fe$51
      Signature Suites Santa Fe

      Signature Suites Santa Fe

      Av. Santa Fe No. 498, Mexico City
      • Free Cancellation
      • Reserve now, pay when you stay
      3.0 out of 5.0
       
       
      3.9 out of 5 (53 reviews)
      Just a little different than pictured.Good experience. Only thing I did not like is that pictures are not accurate. They depict high rise building, but actual suites are below ground. Window facing a construction site and not what it looks like on the pictures. Other than that great place and location.
      JohnNov 1, 2017
      Stadia Suites Santa Fe

      Stadia Suites Santa Fe

      Juan Salvador Agraz # 60, Mexico City
      • Free Cancellation
      • Reserve now, pay when you stay
      4.0 out of 5.0
       
       
      4.4 out of 5 (224 reviews)
      Comfortable and spaciousGreat location. Good rooms. Only thing missing is a bath tub.
      Apr 10, 2018
      Holiday Inn Express Mexico Santa Fe

      Holiday Inn Express Mexico Santa Fe

      Guillermo Gonzalez Camarena 1400, Mexico City
      • Free Cancellation
      • Reserve now, pay when you stay
      2.5 out of 5.0
       
       
      4.1 out of 5 (215 reviews)
      Best relation xomfort/priceIt's very comfortavle rooms and best price at this area
      Mar 20, 2018
      Distrito Capital

      Distrito Capital

      Av. Juan Salvador Agraz 37, Mexico City
        4.0 out of 5.0
         
         
        3.9 out of 5 (185 reviews)
        Breakfast staff needs improvement The staff from the restaurant lacked of attention, you had to stand up from your table in order to get their attention.
        Mar 19, 2018
        The Place Corporate Rentals

        The Place Corporate Rentals

        Av. Prol. Paseo de la Reforma 2742, Mexico City
        • Free Cancellation
        3.0 out of 5.0
         
         
        4.1 out of 5 (37 reviews)
        noisy hotelbad experience, terrible to get in, like a laberint and extemly noisy at nigth
        Feb 12, 2017
        AC Hotel by Marriott Santa Fe

        AC Hotel by Marriott Santa Fe

        Juan Salvador Agraz No 130 Colonia Santa, Mexico City
        • Free Cancellation
        • Reserve now, pay when you stay
        3.5 out of 5.0
         
         
        4.0 out of 5 (36 reviews)
        Very nice stay but some points to be improved1) Menu at the restaurant at night was so scarce 2) It was very hard to know about the breakfast systems (what was included in the included breakfast when the reservation was made).
        TakeshiSep 3, 2017
        Map

        Pocket Guide: Business Hotels in Santa Fe

        Search for hotels in Santa Fe on Expedia. You can easily find your hotels in Santa Fe using one of the methods below:

        • View our selection of featured hotels in Santa Fe
        • Use the map to find hotels in the Santa Fe neighborhood you prefer
        • Use the filters to see hotels in a specific area of Santa Fe, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Santa Fe
        • Enter your travel dates to view the best deals on hotels in Santa Fe - while they last