Apart Hotels in Santee for Rent

Find vacation rentals that suit your style

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Aparthotels
Aparthotels
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Apartments
Apartments

Check prices for these dates

Next weekend
Nov 20 - Nov 22
In two weeks
Nov 27 - Nov 29
In one month
Dec 11 - Dec 13
In two months
Jan 8 - Jan 10

Our top choices for Santee aparthotels

A spacious lobby with a sofa, chairs, a bookshelf, and a large window with a view of greenery.

1. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (515 reviews)
"Front desk service was amazing and love the central location to all the LGBTQ bars and restaurants."
United States
Victor
$102 nightly
The price is $115
Nov 11 - Nov 12
Total with taxes and fees
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
A spacious lounge area with a sofa, a coffee table, and a bar with stools.

2. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,262 reviews)
"Amazing stay! Would definitely come back!"
United States
Dirosia
$144 nightly
The price is $167
Nov 24 - Nov 25
Total with taxes and fees
Marriott Vacation Club®, San Diego
A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

3. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (242 reviews)
"Location is great because it is so close to the airport and you won’t even be able to hear the planes. The room is so roomy and has every utility you need !"
United States
Stephanie
$157 nightly
The price is $177
Nov 29 - Nov 30
Total with taxes and fees
City24 Hotel Little Italy Mission Hills
A modern lobby with a green sofa, a wooden accent wall, and a large plant.

4. Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
Downtown San Diego
8.4 out of 10, Very good, (411 reviews)
"clean, affordable, safe, such a great stay!"
United States
Beatriz
$108 nightly
The price is $124
Nov 16 - Nov 17
Total with taxes and fees
Little Italy Inn - Limited Service Apart Hotel
A neatly made bed with white and gold bedding, two bedside tables with lamps, and three wall-mounted mirrors.

5. Kasa Gaslamp Quarter San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
Downtown San Diego
7.8 out of 10, Good, (241 reviews)
"Wonderful place!"
Canada
Eric
$98 nightly
The price is $111
Nov 16 - Nov 17
Total with taxes and fees
Kasa Gaslamp Quarter San Diego
A modern living room with a dining area, a flat-screen TV mounted on the wall, a sofa, and a bed.

6. The Penn Hotel - Smart TV, AC & Downtown Location!

The Penn Hotel - Smart TV, AC & Downtown Location!
Downtown San Diego
$281 nightly
The price is $318
Nov 10 - Nov 11
Total with taxes and fees
The Penn Hotel - Smart TV, AC & Downtown Location!
A table set for dining with a vase of flowers, two wine glasses, and white bowls on blue placemats.

7. The Penn Hotel - 2BR Above Nightlife & Top Clubs!!

The Penn Hotel - 2BR Above Nightlife & Top Clubs!!
Downtown San Diego
$281 nightly
The price is $318
Nov 10 - Nov 11
Total with taxes and fees
The Penn Hotel - 2BR Above Nightlife & Top Clubs!!
🏙 Bright open-concept living residence—bathed in natural light with views overlooking the vibrant Gaslamp Quarter.

8. The Penn Hotel - Designer 2BR Near Gaslamp & Park

The Penn Hotel - Designer 2BR Near Gaslamp & Park
Downtown San Diego
$281 nightly
The price is $318
Nov 10 - Nov 11
Total with taxes and fees
The Penn Hotel - Designer 2BR Near Gaslamp & Park
A modern hotel room with a bed, a sofa, a coffee table, and a TV displaying the Netflix logo.

9. The Penn Hotel - Walk to Attractions & Sleeps 5!!

The Penn Hotel - Walk to Attractions & Sleeps 5!!
Downtown San Diego
$283 nightly
The price is $320
Nov 10 - Nov 11
Total with taxes and fees
The Penn Hotel - Walk to Attractions & Sleeps 5!!
A modern bedroom with a large bed, a city view through the window, and a round nightstand with a plant.

10. The Penn Hotel - Smart TV, King Bed & Walkability!

The Penn Hotel - Smart TV, King Bed & Walkability!
Downtown San Diego
$281 nightly
The price is $318
Nov 10 - Nov 11
Total with taxes and fees
The Penn Hotel - Smart TV, King Bed & Walkability!
A dining table set with white bowls, wine glasses, and a vase with flowers.

11. The Penn Hotel - Smart TV, AC & Walk to Gaslamp!!!

The Penn Hotel - Smart TV, AC & Walk to Gaslamp!!!
Downtown San Diego
$281 nightly
The price is $318
Nov 10 - Nov 11
Total with taxes and fees
The Penn Hotel - Smart TV, AC & Walk to Gaslamp!!!
A modern kitchen with a central island, bar stools, a sofa, and a dining area with blue chairs.

12. The Penn Hotel -Live Above Gaslamp Nightlife &AC

The Penn Hotel -Live Above Gaslamp Nightlife &AC
Downtown San Diego
$281 nightly
The price is $318
Nov 10 - Nov 11
Total with taxes and fees
The Penn Hotel -Live Above Gaslamp Nightlife &AC
A modern apartment with a kitchen island, seating area, and a bedroom with a large bed and a round mirror.

13. The Penn Hotel - Premium Beds & Gaslamp Nightlife!

The Penn Hotel - Premium Beds & Gaslamp Nightlife!
Downtown San Diego
$281 nightly
The price is $318
Nov 10 - Nov 11
Total with taxes and fees
The Penn Hotel - Premium Beds & Gaslamp Nightlife!
A modern dining table set with white bowls and wine glasses, a decorative vase with white flowers, and a kitchen in the background.

14. The Penn Hotel - Smart TV & King Bed Near Gaslamp!

The Penn Hotel - Smart TV & King Bed Near Gaslamp!
Downtown San Diego
$281 nightly
The price is $318
Nov 10 - Nov 11
Total with taxes and fees
The Penn Hotel - Smart TV & King Bed Near Gaslamp!
A modern hotel room with a bed, a sofa, a dining table, and a large window offering a city view.

15. The Penn Hotel - King Bed, AC & Gaslamp Nightlife!

The Penn Hotel - King Bed, AC & Gaslamp Nightlife!
Downtown San Diego
$294 nightly
The price is $332
Nov 17 - Nov 18
Total with taxes and fees
The Penn Hotel - King Bed, AC & Gaslamp Nightlife!
🛋 Sunlit lounge area—thoughtfully arranged with armchairs and large windows for relaxing or taking in city views.

16. The Penn Hotel - Sleeps 5 & Nightlife Above Clubs!

The Penn Hotel - Sleeps 5 & Nightlife Above Clubs!
Downtown San Diego
$281 nightly
The price is $318
Nov 10 - Nov 11
Total with taxes and fees
The Penn Hotel - Sleeps 5 & Nightlife Above Clubs!
☕ Gourmet kitchen detail—featuring sleek cabinetry, stainless microwave, and under-cabinet lighting.

17. The Penn Hotel - King & Queen Bed | Gaslamp Life

The Penn Hotel - King & Queen Bed | Gaslamp Life
Downtown San Diego
$281 nightly
The price is $318
Nov 10 - Nov 11
Total with taxes and fees
The Penn Hotel - King & Queen Bed | Gaslamp Life
A modern bedroom with a bed, bedside table, lamp, and a mirror.

18. The Penn Hotel - Queen Bed, AC & Walk to Gaslamp!!

The Penn Hotel - Queen Bed, AC & Walk to Gaslamp!!
Downtown San Diego
$189 nightly
The price is $214
Nov 10 - Nov 11
Total with taxes and fees
The Penn Hotel - Queen Bed, AC & Walk to Gaslamp!!
A modern hotel room with a bed, seating area, TV, and a dining table.

19. The Penn Hotel - Sleeps 5 & Gaslamp Nightlife Now!

The Penn Hotel - Sleeps 5 & Gaslamp Nightlife Now!
Downtown San Diego
$281 nightly
The price is $318
Nov 10 - Nov 11
Total with taxes and fees
The Penn Hotel - Sleeps 5 & Gaslamp Nightlife Now!
A modern kitchen with a central island, stainless steel appliances, and a view of a cityscape through the window.

20. The Penn Hotel - Smart TV, AC & Gaslamp Steps Away

The Penn Hotel - Smart TV, AC & Gaslamp Steps Away
Downtown San Diego
$283 nightly
The price is $320
Nov 10 - Nov 11
Total with taxes and fees
The Penn Hotel - Smart TV, AC & Gaslamp Steps Away
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santee

Hikers and nature lovers flock to Mission Trails Regional Park for its 60 miles of scenic trails and stunning views. Santee Lakes Recreation Preserve offers family-friendly fishing, camping, and paddle boating where you'll spot turtles sunning themselves on logs.

See all hotels in Santee
A calm river flowing through a rocky landscape with lush greenery and trees in the background.

Top reviews in Santee

A spacious lounge area with a sofa, a coffee table, and a bar with stools.
Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
Downtown San Diego

10/10 Excellent

Nice property, good rooms, but the area around it is infested with homeless people and drug addicted people, unsafe.
United States
Aibek
Reviewed January 14, 2023
Marriott Vacation Club®, San Diego

Frequently Asked Questions

What can I look forward to during my Santee aparthotel stay?

You'll probably stay more centrally in Santee by choosing an aparthotel. In this relaxing area, you can visit the shops and enjoy the restaurants. Santee is also known for its bars.

What are some top aparthotels for my stay in Santee?

Located 13.5 mi (21.7 km) from Santee, Marriott Vacation Club®, San Diego is a favorite aparthotel featuring 264 apartments with free WiFi and comfy beds as well as hotel amenities like a restaurant. In the area, a couple of other top aparthotels to consider are Little Italy Inn - Limited Service Apart Hotel and Uptown Inn by Vantaggio - Limited Service Apart-Hotel.

How many aparthotels are available in Santee?

On Expedia, there are 19 lodging options in Santee. Though not many aparthotels, we can help you locate places to stay with similar amenities such as kitchens.

What should I see and do in Santee?

Discover top sights in the region such as San Diego Zoo and Mission Bay. Cultural attractions include Off Broadway Live and Creation and Earth History Museum, whereas Sportsplex USA Santee and Santee Lakes are a couple of picturesque spots to enjoy the outdoors. Other popular places to visit in the area include Petco Park and Port of San Diego.

What is an aparthotel?

An aparthotel features the space and privacy found in an apartment and amenities you might expect at a traditional hotel. By booking an aparthotel, you can stay a while and absorb more of the local character in Santee. Enjoy home cooking in a fully-equipped kitchen and having the space to relax after a long day of sightseeing.

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