Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Santiago Center Family Hotels

See all 237 Hotels in Santiago Center
Crowne Plaza Santiago

Crowne Plaza Santiago

Av. Libertador Bernardo O'Higgins 136, Santiago
4.5 out of 5.0
4.3 out of 5 (309 reviews)
Good quality hotel in reasonable locationHotel is close to metro stations and in walking distance of the restaurant and bar districts. Good quality hotel at a reasonable price.
  Jan 8, 2018

$175

$175
Casanoble Hotel Boutique

Casanoble Hotel Boutique

Almirante Montt 440, Santiago
3.5 out of 5.0
4.4 out of 5 (81 reviews)
Perfect place to discover santiagoPerfect location to discover santiago. You can walk everywhere. Nice and well decorated. Perfect place
  Jan 6, 2018

$110

$110
Departamentos Amoblados Torre Tagle

Departamentos Amoblados Torre Tagle

Monjitas 744, Santiago
4.0 out of 5.0
3.8 out of 5 (247 reviews)
Very Happy, thank you!We stayed from 16.09.17 to 01.10.17. My sister and brother arrived first and picked up the keys. The lady on Level Three who the booking is through and who you check in with speaks good English. The staff on the front desk do not. However, this should not really be an issue as you do not have to ...
  Oct 5, 2017

$100

$100
Chileapart.com

Chileapart.com

Merced 562, Of. 819-A, Santiago
3.5 out of 5.0
4.1 out of 5 (170 reviews)
Perfect location for a Great StayTen day stay in Santiago, before heading south. First thing is that the hotel staff are very friendly and helpful. The rooms are laid out well. There is even a fairly large well stocked grocery store located on the street level of the building. Being in the heart of El Centro district, everything ...
  Mar 9, 2017

$65

$65
Hotel Vegas

Hotel Vegas

Londres 49, Santiago
3.5 out of 5.0
3.9 out of 5 (140 reviews)
Excellent location and size, even the room size was adequate.
  Nov 8, 2017

$77

$77
AB Suites Home Fray Camilo

AB Suites Home Fray Camilo

Fray Camilo Hernriquez 463, Santiago
Agustina Suite

Agustina Suite

Huerfanos 1400, Santiago
4.0 out of 5.0
3.6 out of 5 (194 reviews)
Safe neighborhood hotel but..You get what you pay for. You get a letter at the Front Desk with keys and instructions to pass by an office to leave credit card info. Which if you do, even after paying in full with all included you may be sucked into paying more. The area is very safe and so is the building. These apts eems to ...
  Nov 20, 2017

$59

$59
Altiplanico Bellas Artes

Altiplanico Bellas Artes

Santo Domingo 526, Santiago
3.5 out of 5.0
4.7 out of 5 (243 reviews)
Charming place, excellent locationStaff was outstanding, even with a city-wide power outage they kept good spirits and made sure we got on our winery tour. They could not have been more helpful or personable. Very good breakfast, very comfortable bed and nice room with a great shower.
  Jan 21, 2018

$130

$130
AMS Apartments Monjitas

AMS Apartments Monjitas

Monjitas 744, Santiago
4.0 out of 5.0
3.2 out of 5 (83 reviews)
Great central location and secureI really liked the hotel and the location was great. Very close to the metro sta lucia, and barrio lastarria. I was quite impressed with the security of the hotel and cleanliness of the room and communal areas.
  Dec 5, 2017

$65

$65
Andino Departamentos

Andino Departamentos

Huerfanos 1400 depto 1304, Santiago
3.5 out of 5.0
3.6 out of 5 (33 reviews)

$56

$56
Apart Hotel Agustinas Plaza Santiago

Apart Hotel Agustinas Plaza Santiago

Agustinas 681, Santiago
3.5 out of 5.0
3.6 out of 5 (14 reviews)

$75

$75
Apartamentos Los Bosques

Apartamentos Los Bosques

Lord Cochrane 376, Santiago
3.5 out of 5.0
5.0 out of 5 (8 reviews)
Nice View apartmentSmall apartamento but nice and clean and It has a nice View of the city, very close to supermarket. Very close to all turism places by walking I can recomend it
  Dec 3, 2017

$93

$93
Apart Urbano Bellas Artes

Apart Urbano Bellas Artes

Huerfanos 547, Santiago
3.5 out of 5.0
3.3 out of 5 (26 reviews)
Good Location very close to MercedesLocation is great. It is not a hotel, so not much service, but you have a supermarket just downstairs, very convenient. Staid in 2 apartments, both good. Good value for money.
  Jan 19, 2015
Apartments Central Rent

Apartments Central Rent

Lord Cochrane 136, Santiago, Santiago
3.5 out of 5.0
5.0 out of 5 (2 reviews)
Comfortable apartment in the center of SantiagoOur stay was a very pleasant experience. We could check in an hour earlier, the owner was very pleasant. The apartment itself was spacious enough for a vacation for four people, it featured two separate bedrooms, an equipped kitchenette, a small living room with a large flat-screen TV (which we never ...
  Oct 30, 2016
BMB Suites Apartments

BMB Suites Apartments

Huerfanos 1400, Of 214 Torre B, Santiago
3.5 out of 5.0
3.7 out of 5 (47 reviews)
Very convenient location and friendly staff.I've stayed at the hotel 3 times in the past two months.. I like to go there because it is within walking distance of 3 different metro lines, the city centre and there is a grocery store right across the street. There is an ATM open 24/7 right outside the main door in plain view of the reception. ...
  Jan 29, 2014

$64

$64
Casaltura The Boutique Hostel

Casaltura The Boutique Hostel

San Antonio #811, Santiago
3.0 out of 5.0
3.6 out of 5 (95 reviews)
The roof garden made it very special. Met people from all over the world , sat on the roof garden had a beer and a laugh . Great place to stay. Even better when good people are there.
  Feb 18, 2017

$53

$53
Chile Lindo Hostel

Chile Lindo Hostel

Moneda 2514, Santiago
2.0 out of 5.0
3.5 out of 5 (10 reviews)
Nice hostal close to downtown.Excellent staff. Good facilities. Just, you must take care of your food, you must stored in your room.
  Nov 7, 2015
Map

Recently booked Family Hotels in Santiago Center

Hotel Fundador
3.5 out of 5.0
Last booking: 2 hours ago
Hotel Magnolia
4.0 out of 5.0
Last booking: 14 hours ago
Gen Rooms
4.0 out of 5.0
Last booking: 16 hours ago
Hotel Sommelier Boutique
4.0 out of 5.0
Last booking: 44 hours ago

All set for a vacation your family will remember forever? Discover why so many travelers like you have booked a trip to Santiago Center this year. Travelers are increasingly showing interest in this city due to all the interesting attractions and activities you'll find in town. You and your relatives will find plenty of time to bond and spend quality time together, and who knows, you may even meet some vacationing families or locals during your stay!

Pinpoint the Ultimate Santiago Center Family Hotel

You've already told your kids about your big vacation idea, so now you're all set to reserve the greatest family hotel in Santiago Center. Here at Expedia.com, we have many hotel options, so you and your loved ones won't be left wanting. Because we have such various options, you and your family won't have any issue uncovering a place that aligns with all your vacation desires. Some have on-site attractions, while others are located in the heart of all the city action. No matter what kind of family vacation you're in search of, you'll find the ideal spot to temporarily call home.

As Santiago Center continues to climb in popularity, everyone is flocking here for a family vacation. In fact, this area saw lots of visitors last year, and you can read all the useful tips they left in our review section. You'll be blown away at how many people would tell others to stay at their hotel! As soon as you open the door to your room, you'll see why these places were so well received. The rooms are clean and tidy, while the property grounds are especially appealing. From nice rooms to even nicer hotel staff, you and your family are sure to be spoiled.

It's always a good time in Santiago Center, and your family will be sad to return home. Forget day dreaming about your trip. This is the ultimate time to book. Reserve your Santiago Center family hotel and get ready to receive the parent of the year award!