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Your Santiago Vacation

Enjoy the urban city of Santiago with a tailor-made Santiago vacation package and immerse yourself in all it can offer. From its rich history and cultural experiences to its lively atmosphere, prepare to fall for the unique charms of this vibrant destination. Parque Acuatico Italia Guadalupe Panama, Catedral of Santiago Apostol and Plaza Banconal are just some of the sights you'll want to see during your trip to Santiago. A few quick clicks is all it takes to put together the perfect Santiago vacation on Expedia.

The Latest Santiago vacation packages

Price found within the past 48 hours. Click for updated prices.
The Gray by Wynwood House
Central Hotel Panama Casco Viejo
Villa Botero By Casa Mojito B&B
NAYARA Bocas del Toro
La Coralina Island House
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Discover the most popular places to visit in Santiago

Santiago Hotel Deals

Hotel Gran David

Hotel Gran David

3.5 out of 5
Vía Interamericana, Santiago, Veraguas
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $78 total per night from Aug 25 to Aug 26
$78 total
Aug 25 - Aug 26
Total with taxes and fees
8.4/10 Very Good! (324 reviews)
"👍"

Reviewed on Aug 4, 2025

Hotel Gran David
HOTEL PLAZA COROTÚ

HOTEL PLAZA COROTÚ

2 out of 5
Carr. Panamericana, Santiago, Provincia de Veraguas
9/10 Wonderful! (19 reviews)
"They will wash and laundry for a reasonable fee."

Reviewed on Feb 24, 2025

HOTEL PLAZA COROTÚ
Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone

Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone

2 out of 5
Santiago
Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Things to do in and around Santiago

Experience the vibrant culture and outdoor adventures in Santiago, Veraguas, Panama. Enjoy exciting activities like adventure tours and sightseeing excursions, or explore unique Patagonia and Easter Island tours with expert guides. The city also offers a variety of shopping centers and resorts for relaxation after a day of exploration. Don’t miss the chance to immerse yourself in the local scene and discover all that Santiago has to offer.

Shopping

In Santiago, visit Cerámica La Peña and the Artisan Market, both just 1 mile away, offering vibrant local crafts and souvenirs. If you're up for a drive, head to the Mercado, located 29 miles away, for an authentic shopping experience filled with local goods and vibrant city vibes.

Recreation

Omar Torrijos Herrera Stadium offers an energetic atmosphere for sports enthusiasts, perfect for engaging in various recreational activities. For a more tranquil experience, visit Los Pozos Termales, located 7 miles from Santiago, where you can unwind in soothing thermal waters, embracing relaxation and wellness.

Adventure

Experience thrills at Parque Acuatico Italia Guadalupe Panama, a vibrant waterpark located 2 miles from Santiago. Enjoy exciting water slides, wave pools, and lazy rivers, perfect for family fun and adventure. Relax in the sun or challenge your friends to a race—there’s something for everyone.

Nightlife

Santiago's nightlife offers vibrant energy with venues like La Casona for live music and dancing, or the laid-back atmosphere at Bar El Sapo for casual drinks. Enjoy local flavors at nearby eateries while mingling with friendly locals and fellow travelers in this lively Panamanian city.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions in and around Santiago

Located in Veraguas, Panama, Santiago is an ideal destination for beach lovers and culture enthusiasts alike. Visitors can explore attractions such as the national parks, historic cathedral, and lively piazza. Whether you seek adventure, scenic views, or cultural experiences, Santiago offers a diverse range of points of interest that cater to every traveler. Don't miss out on discovering the top attractions that this charming city has to offer.

  • Parque Nacional Cerro Hoya: Located a mile from Santiago, this national park offers stunning landscapes and thrilling outdoor adventures. Explore diverse ecosystems, hike scenic trails, and immerse yourself in the natural beauty of Panama.
  • Catedral of Santiago Apostol: Situated in the heart of Santiago, this historic cathedral showcases beautiful architecture and rich cultural heritage. Experience the serene atmosphere and appreciate the local traditions that have shaped this spiritual landmark.
  • Plaza Banconal: This vibrant square in Santiago is a hub of cultural activity. Stroll through the plaza, enjoy local events, and soak in the lively city vibes while appreciating the surrounding architecture and community spirit.

Best time to go to Santiago

The best time to visit Santiago can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santiago falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature in Santiago falls in November, visitor numbers are average and weather is mostly with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January77.9°F (25.5°C)No RainSunnySlightly HighSlightly Low
February79.7°F (26.5°C)No RainSunnySlightly HighSlightly High
March81.1°F (27.3°C)No RainSunnyAverageAverage
April81.5°F (27.5°C)Light RainMostly SunnyAverageAverage
May79.3°F (26.3°C)Frequent RainMostlySlightly LowSlightly Low
June78.1°F (25.6°C)Frequent RainMostlyAverageSlightly Low
July77.7°F (25.4°C)Frequent RainMostlySlightly HighAverage
August77.5°F (25.3°C)Frequent RainMostlyAverageAverage
September77.2°F (25.1°C)Frequent RainMostlyAverageAverage
October76.5°F (24.7°C)Frequent RainMostlySlightly LowAverage
November75.9°F (24.4°C)Frequent RainMostlyAverageSlightly High
December76.5°F (24.7°C)Light RainMostly SunnySlightly LowSlightly High

Tips to save on your trip to Santiago

  • Take advantage of package deals on Expedia and combine flights, hotels, or car rentals for a convenient and cost-effective trip to Santiago.
  • Consider traveling to Santiago during the low season (January and May to June) for more affordable options.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

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Frequently asked questions

How much does a Santiago vacation package cost?
You can pick up a vacation package to this popular destination from $764 on Expedia. But how much your vacation to Santiago costs will depend on the length of stay, season and hotel choice.
What are the cheapest months to go to Santiago?
May, July and September are the best times to look for cheap Santiago vacation packages. Choosing to travel in less busy months means you can typically find reduced prices on accommodations and flights.
How many days is enough for Santiago?
With a well-organized itinerary, you can easily visit the main Santiago sights in a few days. But if you'd like to venture off the beaten track or go on day trips, think about booking your Santiago vacation for longer.
Is it worth booking a vacation package to Santiago?
Whether you're planning to visit attractions like Parque Acuatico Italia Guadalupe Panama and Catedral of Santiago Apostol, or eager to experience its top-notch shopping and culture, a Santiago vacation is sure to exceed your expectations. Book your getaway with Expedia and discover why Santiago is such a good vacation destination.
How to find the best Santiago package deals?
Start your search for a Santiago package deal by entering your destination and travel dates under our "Packages" tab. Then add some filters, like "Property type" and "Amenities," to fine-tune the results to your exact needs. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the perfect Santiago package deal right away, simply switch up your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santiago adventure underway.
Is it cheaper to book a Santiago vacation as a package?
An Expedia vacation package could land you significant savings when compared to arranging flights and accommodations separately. Better still, you can personalize your Santiago escape to match your exact needs. Choose your preferred flight time, select the hotel type and add a rental car. Browse our great deals to see how much you can save.
When to book a vacation package to Santiago?
Enjoy incredible discounts by reserving your flights ahead of time with Expedia. If being spontaneous is more your thing, take advantage of our last-minute deals for a spur-of-the-moment Santiago trip.
Does Expedia offer Book Now, Pay Later Santiago vacation packages?
Set off on your perfect escape to Santiago with our Book Now, Pay Later vacations. There's no need to scrimp and save or wait until the next payday — we've partnered with online lender Affirm to give you more flexibility and choice. Our vacation packages with payment plans mean you can spread the total cost across 3, 6 or 12 months. With no hidden or late payment fees, it's a breeze to stay on budget and snag great deals before they sell out.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.