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Santo Domingo Vacation Rentals

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Vacation Rentals in Santo Domingo

Family Cabin, Patio, Mountain View | Premium bedding, minibar, blackout drapes, free WiFi
Cabañas el Manantial

Cabin in Moyagalpa

3.0 star property
10.0 out of 10, Exceptional, (2)
"The place was not very far from the Moyogalpa, yet it seemed so surreal and quiet off of the main road. The guard was very attentive to service and respectful. The cabin was felt so cozy and the environment was very inviting. The cabin came with every amenity you need from a fridge to a stove and a coffee pot. Upon arrival, we received a very rare but pleasing welcome to Ometepe brief with good places to tour to on a map with some coffee. It felt very personalized for such a great price. If you...
United States
Rafael
$50 nightly
The price is $58
Jan 2 - Jan 3, 2026
Total with taxes and fees
Cabañas el Manantial
Exterior detail
Standard Bungalow

Vacation Home in Esquipulas

$80 nightly
The price is $80
Dec 31 - Jan 1, 2026
Total with taxes and fees
Standard Bungalow
Property grounds
Cabañas El Bamboo

Cabin in Altagracia

3.0 star property
$43 nightly
The price is $50
Dec 5 - Dec 6
Total with taxes and fees
Cabañas El Bamboo
Exterior
Two-Bedroom Bungalow

Vacation Home in Esquipulas

$80 nightly
The price is $80
Dec 31 - Jan 1, 2026
Total with taxes and fees
Two-Bedroom Bungalow
Property grounds
Deluxe Bungalow with Garden View

Vacation Home in moyogalpa

$60 nightly
The price is $60
Dec 31 - Jan 1, 2026
Total with taxes and fees
Deluxe Bungalow with Garden View
Terrace/patio
Unwind in Style: Cozy Bungalow with All the Comforts of Home in the Ometepe

Vacation Home in Altagracia

10.0 out of 10, Exceptional, (2)
"Beautiful accommodation with a breathtaking view! The location is perfect – ideal for a relaxing vacation. The apartment is modern, very clean, stylish, and authentically decorated. Nothing is missing; it has everything you could possibly need. The perfect place for an unforgettable stay. Highly recommended!"
United States
Tom H.
$95 nightly
The price is $95
Dec 5 - Dec 6
Total with taxes and fees
Unwind in Style: Cozy Bungalow with All the Comforts of Home in the Ometepe
Property grounds
Private cottage on the shores of the lake on the wonderful island of Ometepe

Cabin in Altagracia

$40 nightly
The price is $43
Dec 8 - Dec 9
Total with taxes and fees
Private cottage on the shores of the lake on the wonderful island of Ometepe
Terrace/patio
Boutique Bungalow with Kitchen, Terrace & Views

Vacation Home in Altagracia

$74 nightly
The price is $74
Dec 6 - Dec 7
Total with taxes and fees
Boutique Bungalow with Kitchen, Terrace & Views
Terrace/patio
Casa Nicaraús

Vacation Home in Moyogalpa

Casa Nicaraús
Private kitchen
Peaceful 2-bedroom house with comfortable beds and WiFi

Vacation Home in Rivas

Peaceful 2-bedroom house with comfortable beds and WiFi
Property grounds
4-bedroom house in fabulous Isla de Ometepe with AC, WiFi

Vacation Home in Isla de Ometepe

4-bedroom house in fabulous Isla de Ometepe with AC, WiFi
1 bedroom, desk, free WiFi, bed sheets
Hostal Brisas Ometepe Island

Apartment in Rivas

8.0 out of 10, Very Good, (1)
$45 nightly
The price is $49
Dec 31 - Jan 1, 2026
Total with taxes and fees
Hostal Brisas Ometepe Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santo Domingo Hotel Reviews

Cabañas el Manantial

Cabañas el Manantial

10/10 Excellent
"The cabins were very comfortable and clean. We really appreciated the kitchen. The views were amazing - a beautiful and peaceful place to relax and unwind. Danilo and Reynaldo were amazing hosts. Danilo was able to connect us with a hiking guide and help with translation. "
Gail 3-night trip
Posted 5 days ago
Cabañas el Manantial

Find out more about Santo Domingo

Everything you need to know about Santo Domingo vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santo Domingo vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santo Domingo vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santo Domingo vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santo Domingo. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santo Domingo in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $43 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santo Domingo rentals

At Expedia, we put the best Santo Domingo vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santo Domingo rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santo Domingo vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santo Domingo. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in Santo Domingo?

Yes, you can find vacation rentals close to top local attractions in Santo Domingo, or you can go with a more remote option if you'd like a relaxing place to stay.

What are some of the best vacation home rentals that Santo Domingo has to offer?

Standard Bungalow: This vacation home rental near Santo Domingo offers a patio, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, kitchenware, and a coffee maker.

What can I see and do in Santo Domingo?

Santo Domingo Beach and Lake Nicaragua are a couple of lovely local spots to get outside and enjoy nature. Ojo de Agua Park and Maderas Volcano are a couple of places you'll find in the larger area.

What are vacation rentals like in Santo Domingo?

Vacation rentals are private properties you can book for a short or long stay in Santo Domingo. Vacation rentals offer extras like kitchens and laundry facilities so you'll have everything you want. If you're concerned about a sanitized environment, vacation rentals can offer a sense of privacy away from shared hotel elevators and lobbies packed with people while still allowing you to travel. You'll also find more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive option for family trips or small group gatherings.