Title: The Best Hotels Closest to Science Center of Iowa in Des Moines for 2026 | Expedia.com [Downtown Des Moines Travel Guide](https://expedia.com/Des-Moines-Downtown-Des-Moines.dx6060027)[Car Rentals in Science Center of Iowa](https://expedia.com/Car-Rentals-In-Science-Center-Of-Iowa.d6075028.Car-Rental-Guide)[Science Center of Iowa Vacations](https://expedia.com/Science-Center-Of-Iowa-Downtown-Des-Moines.d6075028.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Feb 23 - Feb 24](https://www.expedia.com/Hotel-Search?regionId=6075028&startDate=2026-02-23&endDate=2026-02-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 24 - Feb 25](https://www.expedia.com/Hotel-Search?regionId=6075028&startDate=2026-02-24&endDate=2026-02-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=6075028&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=6075028&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Science Center of Iowa hotels ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/a4499f56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/5d53b60c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/71578742.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/31b1da89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Des Lux Hotel [](https://www.expedia.com/Des-Moines-Hotels-Des-Lux-Hotel.h9781455.Hotel-Information) Court District, 0.5 mi from Science Center of Iowa 9.8/10 Exceptional (1,050 reviews) "Great stay will do again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew $152 nightly $170 total Feb 26 - Feb 27 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Des-Lux-Hotel.h9781455.Hotel-Information) ![Dinner served](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/72ac6d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/293ddc22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/bee30b62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/e9d1d1c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Fort Des Moines, Curio Collection by Hilton [](https://www.expedia.com/Des-Moines-Hotels-Hotel-Fort-Des-Moines.h9375.Hotel-Information) Western Gateway, 0.5 mi from Science Center of Iowa 9.6/10 Exceptional (1,088 reviews) "Clean hotel from top to bottom, friendly staff, and great food! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John $144 nightly $161 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Hotel-Fort-Des-Moines.h9375.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/45000000/44920000/44914200/44914120/091412b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/45000000/44920000/44914200/44914120/5c0974c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/45000000/44920000/44914200/44914120/34d6d27a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/45000000/44920000/44914200/44914120/e56a1688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Surety Hotel, Autograph Collection [](https://www.expedia.com/Des-Moines-Hotels-Surety-Hotel.h44914120.Hotel-Information) Court District, 0.3 mi from Science Center of Iowa 9.4/10 Exceptional (1,002 reviews) "Fantastic hotel; great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cody $169 nightly $189 total Mar 13 - Mar 14 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Surety-Hotel.h44914120.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/91d6d514.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/d1c0acc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/4f60096d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/f9defb4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staybridge Suites Des Moines Downtown by IHG [](https://www.expedia.com/Des-Moines-Hotels-Staybridge-Suites-Des-Moines-Downtown.h13300681.Hotel-Information) Historic East Village, 0.5 mi from Science Center of Iowa 9.4/10 Exceptional (1,004 reviews) "Nice stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dave $89 nightly $100 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Staybridge-Suites-Des-Moines-Downtown.h13300681.Hotel-Information) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/53b90d46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/7f9d044a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/5991d039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/b31ca2c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Des Moines Downtown by IHG [](https://www.expedia.com/Des-Moines-Hotels-Holiday-Inn-Express-Suites-Des-Moines-Downtown.h12756236.Hotel-Information) Downtown Des Moines, 0.5 mi from Science Center of Iowa 9.2/10 Wonderful (994 reviews) "Great room, good breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason $99 nightly $111 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Holiday-Inn-Express-Suites-Des-Moines-Downtown.h12756236.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/17000000/16530000/16525800/16525760/dcec07a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/17000000/16530000/16525800/16525760/1225329f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/17000000/16530000/16525800/16525760/e3727c53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/17000000/16530000/16525800/16525760/2feb61a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel Des Moines East Village [](https://www.expedia.com/Des-Moines-Hotels-AC-Hotel-Des-Moines-East-Village.h16525760.Hotel-Information) Historic East Village, 0.6 mi from Science Center of Iowa 9.2/10 Wonderful (407 reviews) "Great hotel in a great location in downtown Des Moines " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul $151 nightly $169 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-AC-Hotel-Des-Moines-East-Village.h16525760.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/22000000/21330000/21321600/21321542/3d4c6021.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/22000000/21330000/21321600/21321542/b236a38e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/22000000/21330000/21321600/21321542/c9522ed2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch flat-screen TV with premium channels, TV, pay movies](https://images.trvl-media.com/lodging/22000000/21330000/21321600/21321542/a8a15c92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Des Moines Downtown [](https://www.expedia.com/Des-Moines-Hotels-Hilton-Des-Moines-Downtown.h21321542.Hotel-Information) Downtown Des Moines, 0.6 mi from Science Center of Iowa 9.0/10 Wonderful (1,000 reviews) "Great location and parking accommodation." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matt $155 nightly $173 total Mar 13 - Mar 14 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Hilton-Des-Moines-Downtown.h21321542.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7900000/7897600/7897548/f0edf04c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7900000/7897600/7897548/c095d752.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/8000000/7900000/7897600/7897548/0e9a7aad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/8000000/7900000/7897600/7897548/aa051923.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Des Moines Downtown [](https://www.expedia.com/Des-Moines-Hotels-Hampton-Inn-Suites-Des-Moines-Downtown.h7897548.Hotel-Information) Court District, 0.1 mi from Science Center of Iowa 8.6/10 Excellent (1,002 reviews) "The room was clean and comfortable. The location was wonderful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy $106 nightly $118 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Hampton-Inn-Suites-Des-Moines-Downtown.h7897548.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/7000000/6470000/6468200/6468142/69eea272.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/7000000/6470000/6468200/6468142/c0c4d0dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/7000000/6470000/6468200/6468142/23e72649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/7000000/6470000/6468200/6468142/0898edfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn Des Moines Downtown [](https://www.expedia.com/Des-Moines-Hotels-Residence-Inn-Des-Moines-Downtown.h6468142.Hotel-Information) Court District, 0.1 mi from Science Center of Iowa 8.6/10 Excellent (589 reviews) "The room was spotless and the staff at check in were some of the friendliest we have met! We would give it 10 stars if we could! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew $96 nightly $107 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Residence-Inn-Des-Moines-Downtown.h6468142.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/54000000/53960000/53952800/53952761/f0e0fcc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment, 2 Bedrooms, Non Smoking, 2 Bathrooms (Self Check-in with Virtual Front Desk) | Living area | 49-inch Smart TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/54000000/53960000/53952800/53952761/dcac64b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Apartment, 1 King Bed with Sofa bed, Non Smoking (Self Check-in with Virtual Front Desk) | Private kitchen | Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/54000000/53960000/53952800/53952761/f797da5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/54000000/53960000/53952800/53952761/fba06a98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kasa Downtown Des Moines [](https://www.expedia.com/Des-Moines-Hotels-Kasa-Des-Moines-Downtown-Apartments.h53952761.Hotel-Information) Downtown Des Moines, 0.5 mi from Science Center of Iowa 9.0/10 Wonderful (114 reviews) "Excellent stay! Very clean apartment and safe building." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bill $141 nightly $158 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Kasa-Des-Moines-Downtown-Apartments.h53952761.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/37000000/36940000/36938100/36938080/63d184cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/37000000/36940000/36938100/36938080/1137cad4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/36940000/36938100/36938080/537ac8be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/37000000/36940000/36938100/36938080/535602f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Des Moines Downtown [](https://www.expedia.com/Des-Moines-Hotels-Fairfield-Inn-Suites-By-Marriott-Des-Moines-Downtown.h36938080.Hotel-Information) Downtown Des Moines, 0.8 mi from Science Center of Iowa 9.0/10 Wonderful (407 reviews) "Clean, quiet, affordable,and an excellent breakfast! Right across the street from the casey center." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael $96 nightly $108 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Fairfield-Inn-Suites-By-Marriott-Des-Moines-Downtown.h36938080.Hotel-Information) ![2 restaurants, breakfast, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/20000/17000/16933/w4000h2662x0y0-b9dcf24b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 5 AM to midnight, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/17000/16933/e7dcdb07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/17000/16933/56eb4ee4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/17000/16933/724f01ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Des Moines Marriott Downtown [](https://www.expedia.com/Des-Moines-Hotels-Des-Moines-Marriott-Downtown.h16933.Hotel-Information) Downtown Des Moines, 0.5 mi from Science Center of Iowa 8.8/10 Excellent (962 reviews) "Great location, clean, easy check in and check out. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emily $152 nightly $170 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Des-Moines-Marriott-Downtown.h16933.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/10800/10733/3c6db2b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 2 Double Beds | Premium bedding, down comforters, pillowtop beds, desk](https://images.trvl-media.com/lodging/1000000/20000/10800/10733/f27c17ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/10800/10733/82213ac1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/10800/10733/f5fc26df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renaissance Des Moines Savery Hotel [](https://www.expedia.com/Des-Moines-Hotels-Renaissance-Des-Moines-Savery-Hotel.h10733.Hotel-Information) Downtown Des Moines, 0.3 mi from Science Center of Iowa 8.6/10 Excellent (1,002 reviews) "Clean and great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jodi $127 nightly $142 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Renaissance-Des-Moines-Savery-Hotel.h10733.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8300/8217/2189a8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8300/8217/bbd73c52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/8300/8217/949421a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8300/8217/ccf37cef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Event Center [](https://www.expedia.com/Des-Moines-Hotels-Comfort-Inn-Suites-Event-Center.h8217.Hotel-Information) Downtown Des Moines, 0.8 mi from Science Center of Iowa 8.8/10 Excellent (1,008 reviews) "Nice clean rooms with great parking and good breakfast. Easily located downtown " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Glen A. $102 nightly $115 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Comfort-Inn-Suites-Event-Center.h8217.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10700/10622/baae5559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/10700/10622/66a408c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/10700/10622/4530bad7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served](https://images.trvl-media.com/lodging/1000000/20000/10700/10622/d5bc4613.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites Hotel Des Moines Downtown [](https://www.expedia.com/Des-Moines-Hotels-Embassy-Suites-Hotel-Des-Moines-Downtown.h10622.Hotel-Information) Historic East Village, 0.4 mi from Science Center of Iowa 8.2/10 Very Good (1,010 reviews) "Great atmosphere and quiet rooms." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MICHAEL $114 nightly $128 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Embassy-Suites-Hotel-Des-Moines-Downtown.h10622.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3980000/3972200/3972152/0f5c3279.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/4000000/3980000/3972200/3972152/466d6297.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3980000/3972200/3972152/d3c7f8ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![42-inch flat-screen TV with satellite channels, TV](https://images.trvl-media.com/lodging/4000000/3980000/3972200/3972152/719fc843.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Des Moines/Downtown [](https://www.expedia.com/Des-Moines-Hotels-Hyatt-Place-Des-Moines-Downtwn.h3972152.Hotel-Information) Downtown Des Moines, 0.4 mi from Science Center of Iowa 8.2/10 Very Good (1,009 reviews) "Room was great, location is great, and the breakfast was fantastic! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David $101 nightly $113 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Hyatt-Place-Des-Moines-Downtwn.h3972152.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18900/18835/56a1214f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/18900/18835/f2ae5ea9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/18900/18835/58211348.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/18900/18835/784152cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Downtown - Mercy Area by IHG [](https://www.expedia.com/Des-Moines-Hotels-Holiday-Inn-Downtown-Mercy-Area.h18835.Hotel-Information) Downtown Des Moines, 1 mi from Science Center of Iowa 8.0/10 Very Good (1,005 reviews) "Clean room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan $112 nightly $125 total Feb 26 - Feb 27 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Holiday-Inn-Downtown-Mercy-Area.h18835.Hotel-Information) ![Standard Double Room | Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/10000000/9780000/9776200/9776190/be13159b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | Bathroom | Shower, hair dryer, towels](https://images.trvl-media.com/lodging/10000000/9780000/9776200/9776190/eec7fca0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/10000000/9780000/9776200/9776190/13ca4d38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/10000000/9780000/9776200/9776190/39ab6768.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Rest Motel [](https://www.expedia.com/Des-Moines-Hotels-Cozy-Rest-Motel.h9776190.Hotel-Information) Indianola Hills, 1.7 mi from Science Center of Iowa 7.8/10 Good (653 reviews) "This was a no frills place to stay but the room was nice and the front desk guy was friendly. If you are looking for a cheap but nice place to stay, check them out." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chuck $70 nightly $79 total Mar 2 - Mar 3 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Cozy-Rest-Motel.h9776190.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251406/b9f3330e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, free cribs/infant beds](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251406/5d40e40e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251406/a33da0ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251406/4605db88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Des Moines at Drake University [](https://www.expedia.com/Des-Moines-Hotels-Home2-Suites-By-Hilton-Des-Moines-At-Drake-University.h48251406.Hotel-Information) Drake, 2.1 mi from Science Center of Iowa 9.4/10 Exceptional (1,010 reviews) "Clean, spacious, great amenities, and the sheets were super soft." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bryan $89 nightly $100 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Home2-Suites-By-Hilton-Des-Moines-At-Drake-University.h48251406.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17400/17394/9e02de50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking (Study with Chaise) | Premium bedding, pillowtop beds, in-room safe, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/17400/17394/05d77222.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17400/17394/7983d49f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/17400/17394/28a78bd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Des Moines-Airport [](https://www.expedia.com/Des-Moines-Hotels-Hampton-Inn-Des-Moines-Airport.h17394.Hotel-Information) 3.3 mi from Science Center of Iowa 8.8/10 Excellent (1,005 reviews) "Great room/breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leonard $114 nightly $128 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Des-Moines-Hotels-Hampton-Inn-Des-Moines-Airport.h17394.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-10&endDate=2026-03-11®ionId=6075028&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Science Center of Iowa | Property | Star rating | Guest rating | Breakfast included | Pool | Spa | Pet friendly | WiFi included | | | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | --------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/a4499f56.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Des Lux Hotel | 3.5 star property | 9.8Exceptional1,050 reviews | View | | | | | | | ![Dinner served](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/72ac6d3b.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hotel Fort Des Moines, Curio Collection by Hilton | 4.5 star property | 9.6Exceptional1,088 reviews | View | | | | | | | ![Restaurant](https://images.trvl-media.com/lodging/45000000/44920000/44914200/44914120/091412b2.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Surety Hotel, Autograph Collection | 4.0 star property | 9.4Exceptional1,002 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/91d6d514.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Staybridge Suites Des Moines Downtown by IHG | 3.0 star property | 9.4Exceptional1,004 reviews | View | | | | | | | ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/53b90d46.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Holiday Inn Express & Suites Des Moines Downtown by IHG | 2.5 star property | 9.2Wonderful994 reviews | View | | | | | | ## Top Science Center of Iowa Hotel Reviews ![Hotel Fort Des Moines, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/9e4e0ef2_y.jpg) ### Hotel Fort Des Moines, Curio Collection by Hilton 10/10 Excellent "Great room, restaurants, and staff." [](https://expedia.com/Des-Moines-Hotels-Hotel-Fort-Des-Moines.h9375.Hotel-Information) ![Des Lux Hotel](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/e7f9fb30_y.jpg) ### Des Lux Hotel 10/10 Excellent "It was great! I'm doing it again for sure! " [](https://expedia.com/Des-Moines-Hotels-Des-Lux-Hotel.h9781455.Hotel-Information) ![Holiday Inn Express & Suites Des Moines Downtown by IHG](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/7f9d044a_y.jpg) ### Holiday Inn Express & Suites Des Moines Downtown by IHG 10/10 Excellent "A great value for the rate. A newer facility, friendly and helpful staff, nice amenities, good (healthy even!) breakfast, and free on-site parking. The room was clean and very comfortable. I would stay here again." [](https://expedia.com/Des-Moines-Hotels-Holiday-Inn-Express-Suites-Des-Moines-Downtown.h12756236.Hotel-Information) ![Embassy Suites Hotel Des Moines Downtown](https://images.trvl-media.com/lodging/1000000/20000/10700/10622/05e5842f_y.jpg) ### Embassy Suites Hotel Des Moines Downtown 10/10 Excellent "Nice room, good breakfast, kids enjoyed the pool. " [](https://expedia.com/Des-Moines-Hotels-Embassy-Suites-Hotel-Des-Moines-Downtown.h10622.Hotel-Information) ![Hyatt Place Des Moines/Downtown](https://images.trvl-media.com/lodging/4000000/3980000/3972200/3972152/c5d9ac95_y.jpg) ### Hyatt Place Des Moines/Downtown 10/10 Excellent "Skywalk to everything downtown is great" [](https://expedia.com/Des-Moines-Hotels-Hyatt-Place-Des-Moines-Downtwn.h3972152.Hotel-Information) ![Staybridge Suites Des Moines Downtown by IHG](https://images.trvl-media.com/lodging/14000000/13310000/13300700/13300681/91d6d514_y.jpg) ### Staybridge Suites Des Moines Downtown by IHG 10/10 Excellent "The room was wnderful. Brakfast great. Staff were friendly." [](https://expedia.com/Des-Moines-Hotels-Staybridge-Suites-Des-Moines-Downtown.h13300681.Hotel-Information) ![Home2 Suites by Hilton Des Moines at Drake University](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251406/b9f3330e_y.jpg) ### Home2 Suites by Hilton Des Moines at Drake University 10/10 Excellent "Everything was great " [](https://expedia.com/Des-Moines-Hotels-Home2-Suites-By-Hilton-Des-Moines-At-Drake-University.h48251406.Hotel-Information) ![Comfort Inn & Suites Event Center](https://images.trvl-media.com/lodging/1000000/10000/8300/8217/a41cce84_y.jpg) ### Comfort Inn & Suites Event Center 10/10 Excellent "Clean " [](https://expedia.com/Des-Moines-Hotels-Comfort-Inn-Suites-Event-Center.h8217.Hotel-Information) ![Residence Inn Des Moines Downtown](https://images.trvl-media.com/lodging/7000000/6470000/6468200/6468142/69eea272_y.jpg) ### Residence Inn Des Moines Downtown 10/10 Excellent "Everything was grear from room, front desk to kitchen staff. I would recommend ." [](https://expedia.com/Des-Moines-Hotels-Residence-Inn-Des-Moines-Downtown.h6468142.Hotel-Information) ## Hotels near other Science Center of Iowa attractions ### Principal Park 4.5/5 (64 reviews) Catch an event at Principal Park during your trip to Des Moines. Experience the area's great live music and acclaimed theater scene. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6075046) ### Des Moines' Downtown Farmers' Market You can enjoy retail therapy at Des Moines' Downtown Farmers' Market during your trip to Des Moines. Experience the area's great live music and acclaimed theater scene. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=884736698079137792) ### Polk County Courthouse After visiting Polk County Courthouse, make a plan to see the other sights and activities in Des Moines. Experience the lively festivals and great live music in this family-friendly area. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561929896) ### Des Moines Civic Center 4.3/5 (220 reviews) Des Moines Civic Center is just one of the places to see in Des Moines, so why not enjoy the other things to explore during your travels? Experience the area's great live music and acclaimed theater scene. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6170662) ### Walnut Street Bridge You can learn about the history of Des Moines when you stop by Walnut Street Bridge. Experience the area's acclaimed theater scene and great live music. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6075050) ### World Food Prize Hall of Laureates You can spend an afternoon exploring the galleries in World Food Prize Hall of Laureates during your trip to Des Moines. Experience the lively festivals and great live music in this family-friendly area. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561929895) ### Simon Estes Riverfront Amphitheater You can get tickets for a performance at Simon Estes Riverfront Amphitheater during your trip to Des Moines. Experience the area's great live music or attend a sporting event. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6170659) ### Ruan Center Learn about the local history of Des Moines with a stop at Ruan Center. Experience the area's lively festivals or attend a sporting event. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6210743) ## Frequently asked questions ### What are the top-rated hotels near Science Center of Iowa? > [Des Lux Hotel](https://expedia.com/Des-Moines-hotels-Des-Lux-Hotel.h9781455.Hotel-information) > > > Des Lux Hotel offers a luxurious stay just a 13-minute walk from the Science Center of Iowa, with a stellar review rating of 9.6 and a 3.5-star rating. Guests can indulge in a soothing experience at the onsite spa, complete with a hot tub and steam room. This hotel also features complimentary breakfast options, valet parking, and a fitness center, making it a perfect choice for travelers seeking comfort and convenience. > > > [Hotel Fort Des Moines, Curio Collection by Hilton](https://www.expedia.com/Des-Moines-Hotels-Hotel-Fort-Des-Moines.h9375.Hotel-Information) > > > Hotel Fort Des Moines, Curio Collection by Hilton is a stylish 4.5-star hotel located only 13 minutes on foot from the Science Center of Iowa, rated 9.6 by travelers. This hotel provides luxurious amenities such as a fully equipped kitchen in select rooms, valet parking, and a fitness center. Guests can enjoy contactless check-in and daily housekeeping to enhance their stay, making it an excellent option for those looking for top accommodations. > > > [Home2 Suites by Hilton Des Moines at Drake University](https://www.expedia.com/Des-Moines-Hotels-Home2-Suites-By-Hilton-Des-Moines-At-Drake-University.h48251406.Hotel-Information) > > > Home2 Suites by Hilton Des Moines at Drake University is a welcoming 3-star hotel situated 2.5 miles from the Science Center of Iowa, with an impressive review rating of 9.4\. This hotel features an indoor pool and a well-equipped fitness center, perfect for relaxation and keeping active during travels. Guests can enjoy a complimentary buffet breakfast and the convenience of in-room kitchens, making it ideal for longer stays. ### What hotels are within walking distance to Science Center of Iowa? > [Des Lux Hotel](https://expedia.com/Des-Moines-hotels-Des-Lux-Hotel.h9781455.Hotel-information) > > > Des Lux Hotel, rated 9.6 by travelers, is a charming 3.5-star hotel just a 13-minute walk from the Science Center of Iowa. Guests appreciate the soothing spa services, including an onsite spa and hot tub, perfect for relaxation after a day of exploration. The hotel features free breakfast options, a fitness center, and complimentary airport shuttle services, enhancing the stay for visitors to Des Moines. > > > [Hotel Fort Des Moines, Curio Collection by Hilton](https://www.expedia.com/Des-Moines-Hotels-Hotel-Fort-Des-Moines.h9375.Hotel-Information) > > > Hotel Fort Des Moines, Curio Collection by Hilton boasts a remarkable review rating of 9.4 and is a luxurious 4.5-star hotel situated just 13 minutes on foot from the Science Center of Iowa. Guests can enjoy upscale amenities such as a health club and premium bedding for a restful night. The hotel also features valet parking and early check-in options, making it a sophisticated choice for travelers. > > > [Staybridge Suites Des Moines Downtown by IHG](https://www.expedia.com/Des-Moines-Hotels-Staybridge-Suites-Des-Moines-Downtown.h13300681.Hotel-Information) > > > Staybridge Suites Des Moines Downtown by IHG is a well-rated 3-star hotel, with a review rating of 9.4, located a short 13-minute walk from the Science Center of Iowa. This all-suite hotel offers a fully equipped kitchen in each room, ideal for travelers who enjoy cooking. The indoor pool and hot tub provide relaxation opportunities, while the complimentary buffet breakfast helps kickstart the day. ### How much is a hotel near Science Center of Iowa? ### What are the most popular family-friendly hotels near Science Center of Iowa? > [Days Inn & Suites by Wyndham Des Moines Airport](https://www.expedia.com/Des-Moines-Hotels-Days-Inn-Suites-By-Wyndham-Des-Moines-Airport.h49826.Hotel-Information) > > > Days Inn & Suites by Wyndham Des Moines Airport is a family-friendly haven located just 4.3 miles from Science Center of Iowa. With an impressive travelers' rating of 8.6, this hotel offers free daily breakfast and cribs for the little ones. Guests can enjoy an indoor pool, a fitness center, and spacious connecting rooms that make it easy for families to stay together. > > > [Comfort Inn & Suites Event Center](https://www.expedia.com/Des-Moines-Hotels-Comfort-Inn-Suites-Event-Center.h8217.Hotel-Information) > > > Comfort Inn & Suites Event Center is a delightful option for families, situated about a 16-minute walk from Science Center of Iowa. Rated 8.8 by travelers, this hotel features family-friendly amenities like a kitchenette and free cribs. Guests can splash around in the accessible indoor pool, enjoy a complimentary buffet breakfast, and take advantage of nearby parking, making it a convenient choice for families. > > > [Embassy Suites Hotel Des Moines Downtown](https://www.expedia.com/Des-Moines-Hotels-Embassy-Suites-Hotel-Des-Moines-Downtown.h10622.Hotel-Information) > > > Embassy Suites Hotel Des Moines Downtown offers a fantastic family-friendly experience just a 12-minute walk from Science Center of Iowa. This 3.5-star hotel boasts a travelers' rating of 8.2 and includes features such as an indoor pool and kids' meals at the restaurant. Families will appreciate the spacious rooms equipped with kitchenettes, free breakfast, and connecting rooms, ensuring a comfortable stay for everyone. ### Which hotels near Science Center of Iowa offer the best views? > [Comfort Inn & Suites Event Center](https://www.expedia.com/Des-Moines-Hotels-Comfort-Inn-Suites-Event-Center.h8217.Hotel-Information) > > > Comfort Inn & Suites Event Center is a charming hotel located just a 16-minute walk from the Science Center of Iowa, rated 8.8 by travelers. This inviting hotel features a stunning river view, offering travelers a picturesque backdrop during their stay. With amenities such as an indoor pool, fitness center, and complimentary buffet breakfast, travelers can enjoy a comfortable and convenient experience. The rooms come equipped with kitchenettes, refrigerators, and microwaves, making it easy for travelers to feel at home. ### What are the best affordable hotels near Science Center of Iowa? > [Home2 Suites by Hilton Des Moines at Drake University](https://www.expedia.com/Des-Moines-Hotels-Home2-Suites-By-Hilton-Des-Moines-At-Drake-University.h48251406.Hotel-Information) > > > Home2 Suites by Hilton Des Moines at Drake University is a family-friendly option located just 2.5 miles from the Science Center of Iowa. Rated by travelers at an impressive 9.4, this 3-star hotel offers essential amenities including free breakfast on weekends, an indoor pool, and a fitness center accessible 24/7\. Guests can enjoy spacious rooms equipped with kitchen facilities, making it easy to prepare meals for the family. > > > [Staybridge Suites Des Moines Downtown by IHG](https://www.expedia.com/Des-Moines-Hotels-Staybridge-Suites-Des-Moines-Downtown.h13300681.Hotel-Information) > > > Staybridge Suites Des Moines Downtown by IHG is a top-rated family-friendly hotel situated a short 13-minute walk from the Science Center of Iowa. With a review rating of 9.4, this 3-star hotel features free breakfast daily and an inviting indoor pool. Guests can unwind in comfortable suites with kitchenettes, ideal for families needing extra space and convenience during their stay. > > > [Holiday Inn Express & Suites Des Moines Downtown by IHG](https://www.expedia.com/Des-Moines-Hotels-Holiday-Inn-Express-Suites-Des-Moines-Downtown.h12756236.Hotel-Information) > > > Holiday Inn Express & Suites Des Moines Downtown by IHG is conveniently located just a 14-minute walk from the Science Center of Iowa. Travelers rate this family-friendly hotel at 9.2, highlighting its free breakfast and indoor pool as standout features. The hotel also provides essential amenities such as free Wi-Fi and parking, ensuring a stress-free stay for families visiting the area. ### Are there any hotels with pools close to Science Center of Iowa? > [Econo Lodge Inn & Suites Fairgrounds](https://www.expedia.com/Des-Moines-Hotels-Econo-Lodge-Inn-Suites-Fairgrounds.h1705827.Hotel-Information) > > > Econo Lodge Inn & Suites Fairgrounds is located just 3.7 miles from the Science Center of Iowa, offering travelers a cozy stay with an inviting indoor pool. Rated by travelers at 7.2, this hotel features accessible pool amenities, making it ideal for families and those in need of additional support. Guests can also enjoy free self-parking, daily housekeeping, and the convenience of an early check-in option. > > > [Hampton Inn Des Moines-Airport](https://www.expedia.com/Des-Moines-Hotels-Hampton-Inn-Des-Moines-Airport.h17394.Hotel-Information) > > > Hampton Inn Des Moines-Airport, just 4.4 miles from the Science Center of Iowa, boasts a strong travelers' rating of 8.8\. This family-friendly hotel features an accessible indoor pool with sun loungers, offering a perfect spot to relax. Guests will appreciate the complimentary breakfast, free self-parking, and the convenience of a 24-hour airport shuttle, ensuring a stress-free stay. > > > [Quality Inn & Suites Des Moines Airport](https://www.expedia.com/Des-Moines-Hotels-Quality-Inn-Suites-Des-Moines-Airport.h17922.Hotel-Information) > > > Quality Inn & Suites Des Moines Airport is situated 4.5 miles from the Science Center of Iowa, providing families with a comfortable retreat. With a travelers' rating of 7.2, this hotel features an indoor pool and a relaxing hot tub, perfect for unwinding after a day of exploration. Guests can savor a complimentary buffet breakfast, enjoy free self-parking, and take advantage of the 24-hour airport shuttle service. ### What are the best pet-friendly hotels near Science Center of Iowa? > [Surety Hotel, Autograph Collection](https://www.expedia.com/Des-Moines-Hotels-Surety-Hotel.h44914120.Hotel-Information) > > > Surety Hotel, Autograph Collection is a 4-star gem located just an 8-minute walk from the Science Center of Iowa, with an impressive review rating of 9.4\. This hotel is ideal for travelers with pets, offering amenities such as food and water bowls and rooms where both dogs and cats are welcome. Guests can enjoy free cribs, a 24-hour fitness center, and an inviting atmosphere for couples. With nearby winery tours and daily housekeeping, it's a delightful choice for a memorable stay. > > > [Residence Inn Des Moines Downtown](https://www.expedia.com/Des-Moines-Hotels-Residence-Inn-Des-Moines-Downtown.h6468142.Hotel-Information) > > > Residence Inn Des Moines Downtown is a 3-star hotel situated only 3 minutes from the Science Center of Iowa, rated 8.6 by travelers. This pet-friendly hotel welcomes both dogs and cats, ensuring your furry friend is comfortable with in-room amenities. Guests can take advantage of a complimentary buffet breakfast, an indoor pool, and spacious suites complete with kitchens and separate living areas. It's a perfect blend of convenience and comfort for families and pet owners alike. > > > [Hampton Inn & Suites Des Moines Downtown](https://www.expedia.com/Des-Moines-Hotels-Hampton-Inn-Suites-Des-Moines-Downtown.h7897548.Hotel-Information) > > > Hampton Inn & Suites Des Moines Downtown is located just 4 minutes from the Science Center of Iowa and has received a solid review rating of 8.6\. This pet-friendly hotel allows dogs and cats, making it a welcoming choice for travelers with pets. Guests can enjoy complimentary breakfast daily, an indoor pool, and a hot tub for relaxation after a day of exploration. With family-friendly amenities and comfortable accommodations, it's an excellent choice for those traveling with pets. ### Can I book a fully refundable hotel close to Science Center of Iowa? ### Can I find Expedia discounts for hotels near Science Center of Iowa? > *\*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.* ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Des Moines Hotels ](https://www.expedia.com/Des-Moines-Hotels.d601690.Travel-Guide-Hotels) - [Hotels near Downtown Des Moines ](https://www.expedia.com/Downtown-Des-Moines-Des-Moines-Hotels.0-n6060027-0.Travel-Guide-Filter-Hotels) - [Hotels near Court District ](https://www.expedia.com/Court-District-Des-Moines-Hotels.0-n6170624-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Des Moines ](https://www.expedia.com/Des-Moines-Hotels-Cheap-Hotels.0-0-d601690-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels near Principal Park ](https://www.expedia.com/Principal-Park-Hotels.0-l6075046-0.Travel-Guide-Filter-Hotels) - [Hotels near Casey's Center ](https://www.expedia.com/Wells-Fargo-Arena-Hotels.0-l6075036-0.Travel-Guide-Filter-Hotels) - [Hotels near Des Moines Civic Center ](https://www.expedia.com/Des-Moines-Civic-Center-Hotels.0-l6170662-0.Travel-Guide-Filter-Hotels) - 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