Beginning of main content

Seneca Hotel Rooms at the Wyndham Worldwide

Search Flights

Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Seneca Hotels

Search Flight + Hotel

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.

Featured Seneca Wyndham Worldwide Hotels

See all 61 Hotels in Seneca
Days Inn Seneca Clemson SC

Days Inn Seneca Clemson SC

11015 N Radio Station Rd, Seneca
2.0 out of 5.0
3.6 out of 5 (56 reviews)
Close to Clemson Good proximity to Clemson for the price. Room was clean and AC worked well. - 



Recently booked Seneca hotels

Best Western Executive Inn
2.5 out of 5.0
Last booking: 50 minutes ago
Days Inn Seneca Clemson SC
2.0 out of 5.0
Last booking: 15 hours ago

Pocket Guide: Wyndham Worldwide Hotels in Seneca

Search for hotels in Seneca on Expedia. You can easily find your hotels in Seneca using one of the methods below:

  • View our selection of featured hotels in Seneca
  • Use the map to find hotels in the Seneca neighborhood you prefer
  • Use the filters to see hotels in a specific area of Seneca, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Seneca
  • Enter your travel dates to view the best deals on hotels in Seneca - while they last