Photo by Cindy Keese

Find hotels in Seneca, SC from $59

Most hotels are fully refundable. Because flexibility matters.

Save 10% or more on over 100,000 hotels worldwide as a One Key member.

Search over 2.9 million properties and 550 airlines worldwide.

Filter by

Popular filters
Popular filters
Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveler experience
Traveler experience

Compare 1,490 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Where to stay in Seneca

Find the best Seneca areas and neighborhoods for the activities you enjoy most. Learn more about Seneca

More cheap stays in Seneca

Seneca Travel Info

Number of reviews
4,526
Accommodation
1,490 hotels
Highest price
$169
Lowest price
$59
Hotels with family-friendly amenities
19

Frequently asked questions

Where is the best place for a stay in Seneca?

Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel offers free breakfast and free parking. Traveler reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.

What's the top vacation rental in Seneca?

300+ ratings of 4.9! 4/3bb. Covered Dock, 2 Large Decks. View. Sand play pit. : Visitors like this Seneca vacation home rental. It is located on a lake and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and an arcade game room. See all vacation rentals in Seneca.

If I need to cancel my hotel reservation in Seneca, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.

Where can I learn more about changing or cancelling my trip to Seneca?

To find more details about updating your trip to Seneca or cancelling it, click here.

What's the best budget-friendly accommodation in Seneca?

Based on reviews, Quality Inn Seneca US-123 is a popular 2.5-star hotel for our travelers looking for an economical choice, and features free breakfast and free WiFi. View all budget hotels in Seneca.

What's the best place to stay for a family vacation to Seneca?

Tru by Hilton Seneca Clemson is a hotel with free parking and free breakfast, and it's a top choice on Expedia for families. Other good options for your stay with the kids include Days Inn by Wyndham Seneca / Clemson Area and Best Western Seneca-Clemson. Attractions in the area like Ultimate Action Sports and Georgia Visitor Information Center - Lavonia are also fun for kids of all ages. Find more child-friendly accommodations in Seneca.

What's the best pet-friendly accommodation in Seneca?

Quality Inn Seneca US-123 is a top hotel for people traveling with their pets, and offers a seasonal outdoor pool and free WiFi for its human guests. Days Inn by Wyndham Seneca / Clemson Area is another option if you're bringing your pet along. See more pet-friendly hotel accommodations in Seneca.

What are some hotels with pools in Seneca?

Best Western Seneca-Clemson is a top hotel with a seasonal outdoor pool, free WiFi, and free parking. View all hotels with pools in Seneca.

What is the best accommodation for staying close to Greenville-Spartanburg International Airport (GSP)?

Wyndham Garden Greenville Airport is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and a restaurant. It's located 3.8 mi (6.1 km) from Greenville-Spartanburg Intl. Airport. Other good options near the airport include Best Western Greenville Airport Inn and Extended Stay America - Greenville - Airport.

What is staying in Seneca like?

Visitors to Seneca are sure to enjoy the sporting events, lakeside setting, and university setting. Welcoming and scenic, this city also attracts tourists with its coffeehouses. In Seneca, there are 260 hotels and other accommodations to choose from. Find out more about Seneca.

What should I do while I'm visiting Seneca?

Natural beauty is on display at Lake Keowee, Lake Hartwell, and Keowee Reservoir. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. The university setting is a highlight and Clemson University is worth a campus tour. Check out what more to see and do in Expedia's Seneca guide.

What's the weather like in Seneca?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.

Recent reviews of Seneca hotels
Expedia verified reviews