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All ages can have a great time at 25 family friendly properties

Check prices on hotels in Sikeston

Tonight Tonight May 28 - May 29
This weekend This weekend Jun 1 - Jun 3
Next weekend Next weekend Jun 8 - Jun 10

Featured Sikeston Family Hotels

See all 60 Hotels in Sikeston
Auburn Place Hotel And Suites
3265 William St, Cape Girardeau
Auburn Place Hotel And Suites
4.4/5 (437 reviews)

This place is close to lots of restaurants, has a good breakfast included, clean and comfortable. There was a large group with young kids our first night but it quieted down by 10pm and all was good. The down town walking business area and river are a short drive away. We thought it was a very good ...

altText Apr 17, 2018
Pear Tree Inn - Sikeston
2602 E Malone Avenue, Miner
Pear Tree Inn - Sikeston
4.4/5 (463 reviews)

Room was clean and beds were comfortable. Fast check in and check out.

altText May 26, 2018
Best Western Plus Sikeston
120 S Interstate Drive, Miner
Best Western Plus Sikeston
4.3/5 (443 reviews)

Happy with the service given and room is great. Easy access to this hotel and the offer free breakfast. Gentleman at the front desk was excellent!

altText Apr 1, 2018
Drury Inn & Suites Cape Girardeau
3303 Campster Drive, Cape Girardeau
Drury Inn & Suites Cape Girardeau
4.6/5 (181 reviews)

would stay there again and would recommend to friends and family

altText Apr 19, 2018
Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd, Jackson
Comfort Suites Jackson-Cape Girardeau
4.3/5 (309 reviews)

The hotel was fine and clean, The staff at checkin counter expressed that they were tired and falling asleep, which is what I wanted to do. I expected an awake welcoming hotel representative that was eager to help me get rest.

altText Apr 18, 2018
Drury Inn & Suites Jackson MO
225 Drury Lane, Jackson
Drury Inn & Suites Jackson MO
4.7/5 (307 reviews)

easy access off and onto expressway. Clean. Nice breakfast and evening meal plus 2 free cocktails if you'd like. Note: Only restaurants nearby are burgers, pizza and Mexican. Is a remote location good for a quiet night's sleep.

altText May 27, 2018
Holiday Inn Express Hotel & Suites Cape Girardeau I-55
3253 William Street, Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55
4.8/5 (400 reviews)

Beds were very comfortable and we slept great! Our queen bed suite was very large and worth what I paid. I will be staying here in the future!

altText Apr 30, 2018
Dexter Inn
1807 W Business US Highway 60, Dexter
Dexter Inn
3.3/5 (42 reviews)

just needed a place while passing through

altText Nov 20, 2017
Quality Inn Charleston
102 Drake St, Charleston
Quality Inn Charleston
3.9/5 (93 reviews)

This hotel beat out the La Quinta we stayed at prior. The beds were comfortable and the room amenities for the price were decent. Would stay again.

altText Apr 14, 2018
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau
Pear Tree Inn Cape Girardeau Near the Medical Center
4.1/5 (561 reviews)

Hotel staff was very friendly, corteous, and overall very pleasant. Stayed in a newly renovated room, which was very clean. Definitely a great price for the quality of the staff and room. TV/cable was a little outdated, at least in the room I stayed in, but that's the only minor inconvenience I experienced ...

altText May 8, 2018
Historical 'kage House' Short Term Rental Located in "old Town Cape"
, Cape Girardeau
Historical 'kage House' Short Term Rental Located in "old Town Cape"
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4.9/5 (62 reviews)

My friend and I came to see the Trail of Tears, and staying here by the river was perfect and picturesque. This is a nice, clean, spacious historical property and we really enjoyed shopping the antique stores just a block away. Would highly recommend!

altText Apr 12, 2018
Hampton Inn Cape Girardeau I 55 East
207 S Mt Auburn Rd, Cape Girardeau
Hampton Inn Cape Girardeau I 55 East
4.9/5 (138 reviews)

We arrived a bit early to check in, but they had our room ready! Super comfortable beds and the staff is beyond friendly. We had to leave early, before breakfast was being served, and they had a "to go" option in a brown bag. It was wonderful!

altText Apr 25, 2018
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy, Cape Girardeau
Pear Tree Inn Cape Girardeau West
4.3/5 (279 reviews)

First experience staying at a Drury hotel. Did not enjoy walking through cigarette smoke at entrances. Every entrance and exit was through a cloud of smoke. Suggest moving smoking area away from entrances, Shower in room broken. Only water temp was maximum hot, almost scalding. Tried to regulate ...

altText Apr 27, 2018
Baymont by Wyndham Dexter
1608 Hwy Business 60 W, Dexter
Baymont by Wyndham Dexter
3.8/5 (152 reviews)

The hotel was convenient for us. It was close to our family. It was clean. When we first got there, we thought the refrigerator did not work. Found out the next morning, there were too may appliances for that wall socket (2 outlets for a microwave, coffee pot, refrigerator, and hair dryer). This ...

altText Mar 31, 2018
Candlewood Suites Cape Girardeau
485 S Mount Auburn Rd, Cape Girardeau
Candlewood Suites Cape Girardeau
4.3/5 (215 reviews)

It was pleasant

altText Jan 8, 2018
Holiday Inn Express & Suites Sikeston Southwest
115 Hospitality Dr, Sikeston
Holiday Inn Express & Suites Sikeston Southwest
4.4/5 (75 reviews)

Staff was pleasant and the room was besutiful. I was really surprise that the hotel had a full nreakfast

altText May 18, 2018
Americas Best Value Inn Cape Girardeau
2011 North Kingshighway, Cape Girardeau
Americas Best Value Inn Cape Girardeau
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3.3/5 (266 reviews)

No complaints. The room was very spacious and comfortable

altText Jan 24, 2016
Americas Best Value Inn & Suites Sikeston
220 S Interstate Dr, Miner
Americas Best Value Inn & Suites Sikeston
3.5/5 (319 reviews)

The suites are nice. They are doing construction but still a great stay

altText Apr 2, 2018
Super 8 by Wyndham Sikeston/Miner Area
2609 E Malone Ave, Miner
Super 8 by Wyndham Sikeston/Miner Area
3.1/5 (231 reviews)

Nice king bed. Next to 24 hour McDonald's. Front desk clerk was nice

altText Sep 26, 2017
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
4.8/5 (76 reviews)

My 17 yr old granddaughter said as good as any 5 star hotel

altText May 11, 2018

All set for a vacation that will go down in the history books? Get your kids together and find out why a great deal of travelers like you have booked a trip to Sikeston this year. Travelers are increasingly showing interest in this city due to all the exciting attractions and activities you'll find in town. Whether you're making friends with other vacationing families or getting travel advice from the locals, you'll leave town happy.

Find the Best Sikeston Family Hotel

It's time to get this family vacation started! Allow us to help. Here at, we invite you to browse through our selection of various hotels. From roomy interiors to places with friendly service, you'll come across exactly what your fam desires. Whether your family wants to get to know the town or simply relax at the hotel, the ideal accommodation is waiting for you to book today.

As Sikeston continues to climb in popularity, everyone is flocking here for a family vacation. In fact, this place saw plenty of visitors last year, and you can read all the useful tips they left in our review section. You'll be blown away at how many people would tell others about their hotel! Once you arrive at your accommodation, you'll see why these places received such good ratings. The rooms are clean and tidy, while the property grounds are especially welcoming. From the amazing rooms to the welcoming staff members, your family will be well on its way to being spoiled.

Your family won't be able to contain their happiness when you schedule a trip to Sikeston. Don't waste another second imagining your getaway. This is the ultimate time to book. Pinpoint your Sikeston family hotel now, and start marking off the days until your vacation officially begins!