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Best Resorts in Sikeston

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Next weekend
Dec 19 - Dec 21
In two weeks
Dec 26 - Dec 28
In one month
Jan 9 - Jan 11
In two months
Feb 6 - Feb 8
No exact matches found, but these alternatives could be just right

Recommended hotels in Sikeston

Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1003)
"Clean room, great location and friendly staff"
United States
Mark
$90 nightly
The price is $103
Dec 16 - Dec 17
Total with taxes and fees
Drury Inn & Suites Sikeston, MO
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1002)
"Great place and staff, very accommodating!"
United States
Megan
$90 nightly
The price is $102
Dec 17 - Dec 18
Total with taxes and fees
Drury Plaza Hotel Cape Girardeau Conference Center
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1001)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
$95 nightly
The price is $107
Dec 22 - Dec 23
Total with taxes and fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lobby
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1003)
"Great stay"
United States
Heather
$70 nightly
The price is $79
Dec 16 - Dec 17
Total with taxes and fees
Pear Tree Inn Cape Girardeau West
Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (663)
"Great place "
United States
GUY
$84 nightly
The price is $91
Jan 7 - Jan 8, 2026
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Free daily full breakfast
Best Western Plus Sikeston

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1003)
"Easy parking , quiet and comfortable bed , we’ll stop again on our way back "
United States
joseph
$71 nightly
The price is $81
Dec 21 - Dec 22
Total with taxes and fees
Best Western Plus Sikeston
Exterior
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (718)
"Stayed one night. Good rate for the Hotel "
United States
Paul
$55 nightly
The price is $63
Dec 14 - Dec 15
Total with taxes and fees
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Business center
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1002)
"Very friendly staff and great breakfast"
United States
Ray
$90 nightly
The price is $102
Dec 16 - Dec 17
Total with taxes and fees
Drury Inn & Suites Cape Girardeau
Lobby
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston
2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1001)
"Everything was clean, staff was friendly "
United States
Matthew
$75 nightly
The price is $86
Dec 16 - Dec 17
Total with taxes and fees
Pear Tree Inn Sikeston
Exterior
Hampton Inn Sikeston

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (442)
"Room was clean and cozy, the check in-out staff were really nice and asked about our stay as well and the breakfast was a nice variety."
United States
Doncheial
$95 nightly
The price is $108
Dec 21 - Dec 22
Total with taxes and fees
Hampton Inn Sikeston
Lobby
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1002)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
$83 nightly
The price is $88
Dec 14 - Dec 15
Total with taxes and fees
Drury Inn & Suites Jackson MO
Lobby
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (468)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
$116 nightly
The price is $131
Dec 22 - Dec 23
Total with taxes and fees
Courtyard by Marriott Cape Girardeau Downtown
Exterior
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (443)
"Staff was great. Hotel was clean. Great sleep. "
United States
Jeffrey
$93 nightly
The price is $105
Dec 21 - Dec 22
Total with taxes and fees
Holiday Inn Express & Suites Sikeston Southwest by IHG
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1002)
"Nice place for a stay at a reasonable price."
United States
Arthur
$70 nightly
The price is $79
Dec 16 - Dec 17
Total with taxes and fees
Pear Tree Inn Cape Girardeau Near the Medical Center
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (139)
"Nice hotel, clean and comfortable "
United States
Laura
$88 nightly
The price is $99
Dec 21 - Dec 22
Total with taxes and fees
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby sitting area
The Riverview

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (470)
"Place was nice and safe"
United States
ryan
$96 nightly
The price is $109
Dec 15 - Dec 16
Total with taxes and fees
The Riverview
Studio, 1 King Bed
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
10.0 out of 10, Exceptional, (1)
"Staff was helpful and professional. The rooms were clean and comfortable "
United States
Michael
$98 nightly
The price is $110
Dec 19 - Dec 20
Total with taxes and fees
Hampton Inn By Hilton Dexter
Room, 2 Queen Beds
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (100)
"It was a nice stay"
United States
Douglas
$87 nightly
The price is $99
Dec 21 - Dec 22
Total with taxes and fees
Tru By Hilton Cape Girardeau
Lobby
Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (681)
"Overall was wonderful customer service and breakfast"
United States
Stephanie
$60 nightly
The price is $67
Jan 1 - Jan 2, 2026
Total with taxes and fees
Quality Inn Cape Girardeau North
Courtyard
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (782)
"Excellent stay"
United States
Christina
$99 nightly
The price is $112
Dec 21 - Dec 22
Total with taxes and fees
Hampton Inn Cape Girardeau I 55 East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sikeston Hotel Reviews

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
" Clean rooms , quiet , excellent hotel staff."
James 1-night trip
Posted 2 days ago
Super 8 by Wyndham Sikeston/Miner Area

Find out more about Sikeston

Sikeston Resorts information

Number of reviews
13,906
Accommodation
0 Resorts
Lowest Price
$63
Highest Price
$131

Frequently asked questions

What can I expect from a resort vacation in Sikeston?
Expedia can help you find resorts and other lodging options that provide similar services and comforts. If you're having trouble finding a resort in Sikeston that meets your needs, try using the search filters to look for hotels, or search for properties that offer amenities like swimming pools or all-inclusive options. We make it simple to book great accommodations so you can focus on creating your trip itinerary.
What can I do in Sikeston?
Travelers come to Sikeston for shopping and other popular activities, and say that there are lots of great restaurants here. Central Park and Sikeston Depot Museum are a few of the interesting sights to visit. In the area, other attractions include River Ridge Winery and Front Street Studio & Art Gallery.
What's the weather like in Sikeston?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.
What's the best way to get to and around Sikeston?
Fly into Cairo, IL (CIR-Cairo Regional), which is located 23.8 mi (38.3 km) from the city center. Otherwise, look for flights into Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is 24.2 mi (38.9 km) away. If you'd like to venture out around the area, you may want to rent a car for your trip.

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