South Eastern Region Vacations & Trips from $1,244
Book a Hotel + Flight or Car together to unlock savings
Your South Eastern Region Vacation
With a South Eastern Region vacation package, you can forget about the stress of planning and just focus on experiencing all this lively destination has on offer. You'll have a long to-do list during your trip to South Eastern Region. One top city you'll want to explore is Valletta. Expedia has flights, hotels and everything else you need to help you create your own customized South Eastern Region vacation today.
Top destinations in South Eastern Region
The Latest South Eastern Region Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hotel Pjazza Merkanti - Boutique Living
$1,244
per person
Nov 18 - Nov 23
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Luqa (MLA)
9.4/10 Exceptional! (144 reviews)
Location was very central. Breakfast was great. I had a very comfortable stay here. It was a bit expensive but you do get what you pay for.
They even have free snacks at 6pm if you stay for 2+ nights
Reviewed on Sep 17, 2026
The Xara Palace Relais & Chateaux
Mdina Old City
$2,404
per person
Dec 26 - Dec 31
just found
Roundtrip non-stop flight included
New York (JFK) to Luqa (MLA)
9.4/10 Exceptional! (365 reviews)
Very friendly check in and reception. Bed very comfortable. Breakfast from great look out point. Set right in the ancient city which is great but made parking a challenge (park in free city lots/street).
Breakfast was a slight let down for this price point. Service could be slow, forgetting items. Overall concept rather fussy with lots of served small items rather than choice/buffet. Also it grates to have paid a significant B&B rate only to be charged top up amounts for cooked items like eggs Benedict.
Food in in house Trattoria restaurant is ok rather than excellent (you are paying a location premium) I’d suggest eating in Rabat
Reviewed on Sep 30, 2026
SU29 Boutique Hotel
$1,351
per person
Nov 18 - Nov 23
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Luqa (MLA)
9.2/10 Wonderful! (211 reviews)
This is an exceptional hotel. We stayed in the Grand Harbour Sky Villa which was an amazing space in the centre of the city. The room had everything that you could want and was stylish and spacious. The reception staff were incredibly helpful and a credit to the hotel. The breakfast was also great, hot and cold with a huge variety for such a small hotel and number of guests. I would recommend this hotel for your stay. The location is also very central with two routes to the main streets and close to bars and restaurants. It is however only accessible by steps so pack light or bring someone strong.
Reviewed on Oct 2, 2026
Where to stay in South Eastern Region
Find the best South Eastern Region areas and neighborhoods for the activities you enjoy most.
Photo by Alan C. Bonnici
Photo by Continentaleurope
Photo by Continentaleurope
San Tumas
When in San Tumas, you can plan a visit to St. Peter's Pool and Pretty Bay, some noteworthy sights in the nearby area.
Bellavista
While Bellavista might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Marsaxlokk Bay and Grand Harbour.
Misraħ Strejnu
While there might not be top attractions in Misraħ Strejnu, you can explore the larger area and discover places like Marsaxlokk Bay and St. Peter's Pool.
Tal-Plier
While Tal-Plier might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Grand Harbour and Inquisitor's Palace.
Zejtun Center
While there might not be top attractions in Zejtun Center, you can explore the larger area and discover places like Marsaxlokk Bay and Hal Saflieni Hypogeum.
Find the Best South Eastern Region Vacation Packages
South Eastern Region Essential Information
Language | Maltese |
|---|---|
Currency | Euros |
Local Welcome | Hawn |
Local Goodbye | Ċaw |
Top Sights | Upper Barrakka Gardens, Lower Barrakka Gardens and Marsaxlokk Bay |
South Eastern Region Hotel Deals
Grand Hotel Excelsior
Great Siege Road Floriana Malta
$183 nightly
$199 total
Nov 2 - Nov 3
Total with taxes and fees
8.8/10 Excellent! (1,003 reviews)
"The hotel was beautiful the staff was friendly and was meticulously clean. We liked the bar area that overlooked the bay. We spent one day on beach and loved going into the ocean. The lunch was very good on the beach and had many choices. I also had a relaxation massage that was amazing. We were ..."
Reviewed on Oct 3, 2026
The Phoenicia Malta - The Leading Hotels of the World
The Mall Floriana Malta
Fully refundableReserve now, pay when you stay
$487 nightly
$525 total
Nov 1 - Nov 2
Total with taxes and fees
9.4/10 Exceptional! (1,001 reviews)
"Comfortable, well-run hotel. Helpful staff, especially the concierge and reception staff. The balconies are stylish but not much use for sitting out - better to opt for a bigger room. The menus are unchanging apart from the "specials"."
Reviewed on Oct 3, 2026
Tritoni Valletta Boutique Hotel
33 Triq Vincenzo Dimech Floriana
Fully refundableReserve now, pay when you stay
$104 nightly
$114 total
Nov 1 - Nov 2
Total with taxes and fees
8.6/10 Excellent! (260 reviews)
"Hotel is in the Middle of everything, and short distance to the bus terminal,clean and quiet, but the best thing about the hotel is the staff, specially the front desk, thank you all for all the help"
Reviewed on Sep 24, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular South Eastern Region attractions
Malta Experience
8.8/10 (1,972 reviews)
Enjoy a show at Malta Experience, a storied theater in Valletta. Stroll along the area's seaside, or simply savor its top-notch restaurants.
Upper Barrakka Gardens
9.0/10 (1,783 reviews)
Perched above Valletta's Grand Harbour is an exquisite park of flowers and statues, from where a cannon salute is fired every day.
Photo by Robby Delaware
St. Johns Co - Cathedral
9.4/10 (738 reviews)
After visiting St. Johns Co - Cathedral, make a plan to see the other sights and activities in Valletta. Wander the area's seaside or simply enjoy one of its top-notch restaurants.
Fort St. Elmo
8.8/10 (1,361 reviews)
This battle-scared fortress has stood watch over Malta’s capital city for more than 400 hundred years. Learn about the historic sieges that took place here through dramatic reenactments.
Photo by Rosmarie Danz
The Valletta Waterfront
9.4/10 (144 reviews)
After visiting The Valletta Waterfront, make a plan to see the other sights and activities in Floriana. Stroll along the seaside in this family-friendly area, or check out its lively bars.
Casa Rocca Piccola
9.0/10 (69 reviews)
Get a glimpse into the lives of an aristocratic Maltese family when you tour this 16th-century palace.
Mediterranean Conference Centre
8.2/10 (138 reviews)
Mediterranean Conference Centre is just one of the places to see in Valletta, so why not enjoy the other things to explore during your travels? Wander the area's seaside or simply enjoy one of its top-notch restaurants.
Grand Masters Palace
8.6/10 (45 reviews)
After visiting Grand Masters Palace, make a plan to see the other sights and activities in Valletta. Stroll along the area's seaside, or simply savor its top-notch restaurants.
What to do in South Eastern Region
Malta: Gozo & Comino Islands, Blue Lagoon & Seacaves Tour
$37
per adult
88% of travellers recommend
Comino: Blue Lagoon, Crystal Lagoon, and Seacaves Tour
$34
per adult
90% of travellers recommend
Malta Boat: Comino Blue Lagoon, Crystal Lagoon, Gozo & Caves
$40
per adult
98% of travellers recommend
Explore a world of travel with Expedia
Other vacations you might like
- Top cities in South Eastern Region
- Vacations and getaways similar to South Eastern Region
- Best vacation destinations by month
- January Vacations and Deals
- February Vacations and Deals
- March Vacations and Deals
- April Vacations and Deals
- May Vacations and Deals
- June Vacations and Deals
- July Vacations and Deals
- August Vacations and Deals
- September Vacations and Deals
- October Vacations and Deals
- November Vacations and Deals
- December Vacations and Deals
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.