South Eastern Region Vacations & Trips from $1,105

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your South Eastern Region Vacation

With a South Eastern Region vacation package, you can forget about the stress of planning and just focus on experiencing all this lively destination has on offer. You'll have a long to-do list during your trip to South Eastern Region. One top city you'll want to explore is Valletta. Expedia has flights, hotels and everything else you need to help you create your own customized South Eastern Region vacation today.

Top destinations in South Eastern Region

A cityscape with prominent domed buildings and a historic church.

Valletta

Valletta
A nighttime cityscape with illuminated buildings reflecting on the water.

Floriana

Floriana
A harbor with numerous boats, a historic cityscape, and a clear sky.

Birgu

Birgu
An aerial view of a city with a prominent cathedral featuring a large red dome, surrounded by urban buildings and streets.

Zabbar

Zabbar
A coastal cityscape with historic buildings, a fortified harbor, and a calm sea at dusk.

Senglea

Senglea
A marina with various boats docked, a large stone wall, and buildings in the background.

Kalkara

Kalkara

The Latest South Eastern Region Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Corinthia Palace Malta

Corinthia Palace Malta

$1,105
per person
Dec 2 - Dec 5
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Luqa (MLA)
9.4/10 Exceptional! (1,002 reviews)
We had an excellent visit. The staff are fantastic. Also, the property is grand and elegant although you can tell it is an older property, which is why we were so happy to have a room that been recently renovated and was is in pristine condition. The Corinthia Palace is a beautiful, classy hotel and we highly recommend it.

Reviewed on Sep 11, 2026

Osborne

Osborne

$1,146
per person
Dec 2 - Dec 5
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Luqa (MLA)
8.6/10 Excellent! (839 reviews)
Great location in the old city section of Valletta. Highly recommend

Reviewed on Sep 4, 2026

SU29 Boutique Hotel

SU29 Boutique Hotel

$1,243
per person
Nov 13 - Nov 18
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Luqa (MLA)
9.2/10 Wonderful! (206 reviews)
We stayed on the 6th floor and the view was spectacular. The room was large with a gorgeous outdoor terrace but sadly it had not been cleaned. We needed to clean this area before we sat there - we then were able to enjoy this lovely space overlooking the harbour and city. Our room included a small kitchenette - not really suitable to cook a meal. Expedia lists this hotel with a laundry - it does not, you need to pay per item. The staff were kind, thoughtful and very helpful and the breakfast was delicious. The location is walkable to all main attractions, close to restaurants and cafes. Just be aware it is a very difficult place to arrive on foot with large/heavy luggage as there are LOADS of stairs and hills. If you take a cab to the Grand Harbour Hotel (best option)- it is ‘only’ about 50 steps up to the hotel - doable. There are no staff to help you with your luggage as it is a small boutique hotel. Would I stay here again, absolutely, the positives definitely outweigh the negatives.

Reviewed on Sep 18, 2026

Hotel Pjazza Merkanti - Boutique Living

Hotel Pjazza Merkanti - Boutique Living

$1,176
per person
Nov 11 - Nov 14
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Luqa (MLA)
9.4/10 Exceptional! (142 reviews)
Location was very central. Breakfast was great. I had a very comfortable stay here. It was a bit expensive but you do get what you pay for. They even have free snacks at 6pm if you stay for 2+ nights

Reviewed on Sep 17, 2026

Radisson Blu Resort & Spa, Malta Golden Sands

Radisson Blu Resort & Spa, Malta Golden Sands

Għajn Tuffieħa
$1,117
per person
Nov 11 - Nov 14
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Luqa (MLA)
9.4/10 Exceptional! (1,006 reviews)
Pros: b

Reviewed on Sep 21, 2026

Where to stay in South Eastern Region

Find the best South Eastern Region areas and neighborhoods for the activities you enjoy most.

San Tumas

When in San Tumas, you can plan a visit to St. Peter's Pool and Pretty Bay, some noteworthy sights in the nearby area.

Bellavista

While Bellavista might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Marsaxlokk Bay and Grand Harbour.

Misraħ Strejnu

While there might not be top attractions in Misraħ Strejnu, you can explore the larger area and discover places like Marsaxlokk Bay and St. Peter's Pool.

Tal-Plier

While Tal-Plier might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Grand Harbour and Inquisitor's Palace.

Zejtun Center

While there might not be top attractions in Zejtun Center, you can explore the larger area and discover places like Marsaxlokk Bay and Hal Saflieni Hypogeum.

Find the Best South Eastern Region Vacation Packages

South Eastern Region Essential Information

Language
Maltese
Currency
Euros
Local Welcome
Hawn
Local Goodbye
Ċaw
Top Sights
Upper Barrakka Gardens, Lower Barrakka Gardens and Marsaxlokk Bay

South Eastern Region Hotel Deals

Grand Hotel Excelsior

Grand Hotel Excelsior

Great Siege Road Floriana Malta
$307 nightly
$332 total
Oct 22 - Oct 23
Total with taxes and fees
Grand Hotel Excelsior
The Phoenicia Malta - The Leading Hotels of the World

The Phoenicia Malta - The Leading Hotels of the World

The Mall Floriana Malta
Fully refundableReserve now, pay when you stay
$616 nightly
$663 total
Sep 29 - Sep 30
Total with taxes and fees
The Phoenicia Malta - The Leading Hotels of the World
Tritoni Valletta Boutique Hotel

Tritoni Valletta Boutique Hotel

33 Triq Vincenzo Dimech Floriana
Fully refundableReserve now, pay when you stay
$143 nightly
$157 total
Oct 5 - Oct 6
Total with taxes and fees
8.6/10 Excellent! (257 reviews)
"Excellent location, modern facilities and great customer service."

Reviewed on Sep 21, 2026

Tritoni Valletta Boutique Hotel
See all 1,047 properties in South Eastern Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular South Eastern Region attractions

An aerial view of a coastal city with dense urban architecture, a prominent church, and a marina filled with boats.

Malta Experience

8.8/10 (1,972 reviews)
Enjoy a show at Malta Experience, a storied theater in Valletta. Stroll along the area's seaside, or simply savor its top-notch restaurants.
See properties
A stone bridge with arches and people sitting on benches.

Upper Barrakka Gardens

9.0/10 (1,783 reviews)
Perched above Valletta's Grand Harbour is an exquisite park of flowers and statues, from where a cannon salute is fired every day.
See properties
An ornate altar with a large chandelier, golden decorations, and a detailed ceiling fresco.
Photo by Robby Delaware

St. Johns Co - Cathedral

9.4/10 (738 reviews)
After visiting St. Johns Co - Cathedral, make a plan to see the other sights and activities in Valletta. Wander the area's seaside or simply enjoy one of its top-notch restaurants.
See properties
A historic stone wall with greenery growing on it, a building with green shutters, and a clear blue sky.

Fort St. Elmo

8.8/10 (1,361 reviews)
This battle-scared fortress has stood watch over Malta’s capital city for more than 400 hundred years. Learn about the historic sieges that took place here through dramatic reenactments.
See properties
A waterfront promenade at night with illuminated buildings and a boat docked by the water.
Photo by Rosmarie Danz

The Valletta Waterfront

9.4/10 (144 reviews)
After visiting The Valletta Waterfront, make a plan to see the other sights and activities in Floriana. Stroll along the seaside in this family-friendly area, or check out its lively bars.
See properties
A street with parked cars and people walking. There is a banner hanging from a building that reads "Casa Rocca Piccola 16th Century Palazzo Open".

Casa Rocca Piccola

9.0/10 (69 reviews)
Get a glimpse into the lives of an aristocratic Maltese family when you tour this 16th-century palace.
See properties

Mediterranean Conference Centre

8.2/10 (138 reviews)
Mediterranean Conference Centre is just one of the places to see in Valletta, so why not enjoy the other things to explore during your travels? Wander the area's seaside or simply enjoy one of its top-notch restaurants.
See properties

Grand Masters Palace

8.6/10 (45 reviews)
After visiting Grand Masters Palace, make a plan to see the other sights and activities in Valletta. Stroll along the area's seaside, or simply savor its top-notch restaurants.
See properties

What to do in South Eastern Region

Malta: Gozo & Comino Islands, Blue Lagoon & Seacaves Tour

Malta: Gozo & Comino Islands, Blue Lagoon & Seacaves Tour

$47
per adult
86% of travellers recommend
Malta: Gozo & Comino Islands, Blue Lagoon & Seacaves Tour
Comino: Blue Lagoon, Crystal Lagoon, and Seacaves Tour

Comino: Blue Lagoon, Crystal Lagoon, and Seacaves Tour

$35
per adult
90% of travellers recommend
Comino: Blue Lagoon, Crystal Lagoon, and Seacaves Tour
Malta Boat: Comino Blue Lagoon,Crystal Lagoon, Gozo & Caves

Malta Boat: Comino Blue Lagoon, Crystal Lagoon, Gozo & Caves

$40
per adult
96% of travellers recommend
Malta Boat: Comino Blue Lagoon, Crystal Lagoon, Gozo & Caves
See all activities in South Eastern Region
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.