South Eastern Region Vacations & Trips from $1,516

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Your South Eastern Region Vacation

With a South Eastern Region vacation package, you can forget about the stress of planning and just focus on experiencing all this lively destination has on offer. You'll have a long to-do list during your trip to South Eastern Region. One top city you'll want to explore is Valletta. Expedia has flights, hotels and everything else you need to help you create your own customized South Eastern Region vacation today.

Top destinations in South Eastern Region

The Latest South Eastern Region Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Rosselli
Iniala Valletta
Il Palazzin Hotel
Radisson Blu Resort, Malta St. Julian's
Deep Blu

Where to stay in South Eastern Region

Get a lay of the land and find the perfect place to stay Learn more about South Eastern Region

Find the Best South Eastern Region Vacation Packages

South Eastern Region Essential Information

Language
Maltese
Currency
Euros
Local Welcome
Hawn
Local Goodbye
Ċaw
Top Sights
Upper Barrakka Gardens, Lower Barrakka Gardens and Marsaxlokk Bay

South Eastern Region Hotel Deals

Grand Hotel Excelsior

Grand Hotel Excelsior

5 out of 5
Great Siege Road Floriana Malta
$264 nightly
The price is $283 total per night from May 30 to May 31
$283 total
May 30 - May 31
Total with taxes and fees
8.8/10 Excellent! (1,010 reviews)
Property is in need of a refresh. Its location means a hike up to everything you want to see.

Reviewed on May 4, 2026

Grand Hotel Excelsior
The Phoenicia Malta - The Leading Hotels of the World

The Phoenicia Malta - The Leading Hotels of the World

5 out of 5
The Mall Floriana Malta
Fully refundableReserve now, pay when you stay
$666 nightly
The price is $714 total per night from May 18 to May 19
$714 total
May 18 - May 19
Total with taxes and fees
9.4/10 Exceptional! (1,002 reviews)
Excellent hotel, the closest hotel to the entrance to the historic walled city of Valletta, where the Knights of the Order of St John built their fort in the late 1500’s.

Reviewed on Apr 24, 2026

The Phoenicia Malta - The Leading Hotels of the World
Tritoni Valletta Boutique Hotel

Tritoni Valletta Boutique Hotel

3 out of 5
33 Triq Vincenzo Dimech Floriana
Fully refundableReserve now, pay when you stay
$146 nightly
The price is $158 total per night from May 5 to May 6
$158 total
May 5 - May 6
Total with taxes and fees
8.6/10 Excellent! (223 reviews)
On arrival, everything went smoothly. Front desk was very helpful and let us store our luggage as we were early. Unfortunately, the A/C and TV were not working and there was no fridge/mini bar as advertised. The front desk staff really was not helpful in resolving any of these issues. On a positive ...

Reviewed on Apr 24, 2026

Tritoni Valletta Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in South Eastern Region

What to do in South Eastern Region

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.