South Eastern Region Vacations & Trips from $1,314

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Your South Eastern Region Vacation

With a South Eastern Region vacation package, you can forget about the stress of planning and just focus on experiencing all this lively destination has on offer. You'll have a long to-do list during your trip to South Eastern Region. One top city you'll want to explore is Valletta. Expedia has flights, hotels and everything else you need to help you create your own customized South Eastern Region vacation today.

Top destinations in South Eastern Region

A cityscape with prominent domed buildings and a historic church.

Valletta

Valletta
A nighttime cityscape with illuminated buildings reflecting on the water.

Floriana

Floriana
An aerial view of a city with a prominent cathedral featuring a large red dome, surrounded by urban buildings and streets.

Zabbar

Zabbar
A harbor with numerous boats, a historic cityscape, and a clear sky.

Birgu

Birgu
A coastal cityscape with historic buildings, a fortified harbor, and a calm sea at dusk.

Senglea

Senglea
A marina with various boats docked, a large stone wall, and buildings in the background.

Kalkara

Kalkara

The Latest South Eastern Region Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Palazzo Violetta

Palazzo Violetta

$1,314
per person
Oct 31 - Nov 6
found 23 hours ago
Roundtrip non-stop flight included
Denver (DEN) to Luqa (MLA)
9.2/10 Wonderful! (547 reviews)
Very clean. Front reception guy we had checking us in was not very welcoming at all. We had a room without a balcony, which was not the best. It was very quiet though.

Reviewed on Sep 29, 2026

SU29 Boutique Hotel

SU29 Boutique Hotel

$1,613
per person
Nov 7 - Nov 13
found 2 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Luqa (MLA)
9.2/10 Wonderful! (211 reviews)
Great location, very friendly and helpful staff

Reviewed on Sep 26, 2026

Iniala Valletta

Iniala Valletta

$2,326
per person
Dec 1 - Dec 5
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Luqa (MLA)
9.8/10 Exceptional! (124 reviews)
A fantastic boutique hotel. Great location and excellent service- cannot fault it in any way.

Reviewed on Sep 22, 2026

Palais Le Brun

Palais Le Brun

$1,333
per person
Dec 14 - Dec 20
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Luqa (MLA)
9.6/10 Exceptional! (941 reviews)
Cute hotel, big clean rooms, nice roof top pool, really good location.

Reviewed on Sep 29, 2026

The Gomerino Hotel

The Gomerino Hotel

$1,385
per person
Dec 14 - Dec 20
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Luqa (MLA)
9.6/10 Exceptional! (1,005 reviews)
The staff were fantastic ! The hotel was fabulous / clean / perfectly located / totally intimate and divine. The rooftop pool looked over the three cities and was the perfect way to relax with a cocktail after site seeing. I will be back. Xxx Gillian, Australia

Reviewed on Sep 29, 2026

Where to stay in South Eastern Region

Find the best South Eastern Region areas and neighborhoods for the activities you enjoy most.
A rocky coastal path with clear blue sea and sparse vegetation.
Photo by Alan C. Bonnici
A coastal cliff with ancient ruins and vegetation.
Photo by Continentaleurope
A coastal cliff with a cave entrance and clear blue waters.
Photo by Continentaleurope

San Tumas

When in San Tumas, you can plan a visit to St. Peter's Pool and Pretty Bay, some noteworthy sights in the nearby area.

A coastal landscape with a rocky outcrop, clear blue sea, and a distant cityscape.

Bellavista

While Bellavista might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Marsaxlokk Bay and Grand Harbour.

A stone building with green doors and a staircase leading up to it.

Misraħ Strejnu

While there might not be top attractions in Misraħ Strejnu, you can explore the larger area and discover places like Marsaxlokk Bay and St. Peter's Pool.

Tal-Plier

While Tal-Plier might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Grand Harbour and Inquisitor's Palace.

Zejtun Center

While there might not be top attractions in Zejtun Center, you can explore the larger area and discover places like Marsaxlokk Bay and Hal Saflieni Hypogeum.

Find the Best South Eastern Region Vacation Packages

South Eastern Region Essential Information

Language
Maltese
Currency
Euros
Local Welcome
Hawn
Local Goodbye
Ċaw
Top Sights
Upper Barrakka Gardens, Lower Barrakka Gardens and Marsaxlokk Bay
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Stay near popular South Eastern Region attractions

An aerial view of a coastal city with dense urban architecture, a prominent church, and a marina filled with boats.

Malta Experience

8.8/10 (1,972 reviews)
Enjoy a show at Malta Experience, a storied theater in Valletta. Stroll along the area's seaside, or simply savor its top-notch restaurants.
See properties
A stone bridge with arches and people sitting on benches.

Upper Barrakka Gardens

9.0/10 (1,783 reviews)
Perched above Valletta's Grand Harbour is an exquisite park of flowers and statues, from where a cannon salute is fired every day.
See properties
An ornate altar with a large chandelier, golden decorations, and a detailed ceiling fresco.
Photo by Robby Delaware

St. Johns Co - Cathedral

9.4/10 (738 reviews)
After visiting St. Johns Co - Cathedral, make a plan to see the other sights and activities in Valletta. Wander the area's seaside or simply enjoy one of its top-notch restaurants.
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A historic stone wall with greenery growing on it, a building with green shutters, and a clear blue sky.

Fort St. Elmo

8.8/10 (1,361 reviews)
This battle-scared fortress has stood watch over Malta’s capital city for more than 400 hundred years. Learn about the historic sieges that took place here through dramatic reenactments.
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A waterfront promenade at night with illuminated buildings and a boat docked by the water.
Photo by Rosmarie Danz

The Valletta Waterfront

9.4/10 (144 reviews)
After visiting The Valletta Waterfront, make a plan to see the other sights and activities in Floriana. Stroll along the seaside in this family-friendly area, or check out its lively bars.
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A street with parked cars and people walking. There is a banner hanging from a building that reads "Casa Rocca Piccola 16th Century Palazzo Open".

Casa Rocca Piccola

9.0/10 (69 reviews)
Get a glimpse into the lives of an aristocratic Maltese family when you tour this 16th-century palace.
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Mediterranean Conference Centre

8.2/10 (138 reviews)
Mediterranean Conference Centre is just one of the places to see in Valletta, so why not enjoy the other things to explore during your travels? Wander the area's seaside or simply enjoy one of its top-notch restaurants.
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Grand Masters Palace

8.6/10 (45 reviews)
After visiting Grand Masters Palace, make a plan to see the other sights and activities in Valletta. Stroll along the area's seaside, or simply savor its top-notch restaurants.
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What to do in South Eastern Region

Malta: Gozo & Comino Islands, Blue Lagoon & Seacaves Tour

Malta: Gozo & Comino Islands, Blue Lagoon & Seacaves Tour

$37
per adult
88% of travellers recommend
Malta: Gozo & Comino Islands, Blue Lagoon & Seacaves Tour
Comino: Blue Lagoon, Crystal Lagoon, and Seacaves Tour

Comino: Blue Lagoon, Crystal Lagoon, and Seacaves Tour

$34
per adult
90% of travellers recommend
Comino: Blue Lagoon, Crystal Lagoon, and Seacaves Tour
Malta Boat: Comino Blue Lagoon,Crystal Lagoon, Gozo & Caves

Malta Boat: Comino Blue Lagoon, Crystal Lagoon, Gozo & Caves

$40
per adult
98% of travellers recommend
Malta Boat: Comino Blue Lagoon, Crystal Lagoon, Gozo & Caves
See all activities in South Eastern Region
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