South Eastern Region Vacations & Trips from $1,621
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Your South Eastern Region Vacation
With a South Eastern Region vacation package, you can forget about the stress of planning and just focus on experiencing all this lively destination has on offer. You'll have a long to-do list during your trip to South Eastern Region. One top city you'll want to explore is Valletta. Expedia has flights, hotels and everything else you need to help you create your own customized South Eastern Region vacation today.
Top destinations in South Eastern Region
Valletta
The Latest South Eastern Region Vacation Packages
Price found within the past 48 hours. Click for updated prices.
San Karlu Hotel
Price was $2,203, price is now $1,621 per person
$1,621
per person
May 4 - May 12
found 1 hour ago
Roundtrip non-stop flight included
Chicago (ORD) to Luqa (MLA)
9.4/10 Exceptional! (235 reviews)
Great communication pre-stay! Fantastic staff throughout the hotel. Friendly and helpful 24 hour reception, wonderful greetings and always making sure everything was making your holiday pleasant. Every area was sparkling clean and the rooms were superb. The free morning breakfast buffet was a great way to start your day, fresh sliced fruits, local pastries, hot breakfast as well. Thank you all for making our stay in Valletta extra special.
Reviewed on Feb 27, 2026
Iniala Harbour House
Save 100% on your flight
Price was $6,065, price is now $4,046 per person
$4,046
per person
Apr 18 - Apr 25
found 1 day ago
Roundtrip flight included
Boston (BOS) to Luqa (MLA)
9.8/10 Exceptional! (109 reviews)
Stunning beautiful oasis in Malta. It was a short but incredible visit.
Reviewed on Oct 9, 2025
Palais Le Brun
Save 100% on your flight
Price was $3,016, price is now $2,048 per person
$2,048
per person
May 4 - May 12
found 1 hour ago
Roundtrip non-stop flight included
Chicago (ORD) to Luqa (MLA)
9.6/10 Exceptional! (837 reviews)
Very enjoyable overall. The one negative item worth mentioning would be the the warmth in one of our rooms. Their AC was not on for the season, as expected. But the room held it's overly warm temperature even with the balcony doors cracked. Not feeling comfortable sleeping with the doors open it made it difficult to sleep.
Reviewed on Mar 12, 2026
The Gomerino Hotel
Price was $2,277, price is now $1,661 per person
$1,661
per person
May 2 - May 9
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Luqa (MLA)
9.6/10 Exceptional! (1,005 reviews)
Absolutely lovely hotel in the heart of Valletta close to all amenities and sights. Wonderful rooftop views of the harbour and the canon bastion. Lovely room with balcony overlooking local streets. Super breakfast selection and such fantastic staff. Would thoroughly recommend this hotel as a place to explore this lovely city.
Reviewed on Mar 10, 2026
Where to stay in South Eastern Region
Get a lay of the land and find the perfect place to stay Learn more about South Eastern Region
San Tumas
When in San Tumas, you can plan a visit to St. Peter's Pool and Pretty Bay, some noteworthy sights in the nearby area.
Find the Best South Eastern Region Vacation Packages
South Eastern Region Essential Information
Language | Maltese |
|---|---|
Currency | Euros |
Local Welcome | Hawn |
Local Goodbye | Ċaw |
Top Sights | Upper Barrakka Gardens, Lower Barrakka Gardens and Marsaxlokk Bay |
South Eastern Region Hotel Deals
Grand Hotel Excelsior
Great Siege Road Floriana Malta
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $164 total per night from Mar 31 to Apr 1
$164 total
Mar 31 - Apr 1
Total with taxes and fees
8.8/10 Excellent! (1,002 reviews)
Rooms need some updates
Reviewed on Mar 12, 2026
The Gomerino Hotel
247 St Paul St Valletta
Fully refundableReserve now, pay when you stay
$214 nightly
The price is $230 total per night from Mar 31 to Apr 1
$230 total
Mar 31 - Apr 1
Total with taxes and fees
9.6/10 Exceptional! (1,001 reviews)
Great location just off the main central streets in Valletta. Lovely breakfast, if a little limited. Some great recommendations from the hotel staff. Il Horza restaurant 3 min walk was excellent. Pool and sauna a nice touch as was rooftop bar.
Reviewed on Mar 12, 2026
Palais Le Brun
101 old bakery street Valletta
Fully refundableReserve now, pay when you stay
$192 nightly
The price is $207 total per night from Mar 27 to Mar 28
$207 total
Mar 27 - Mar 28
Total with taxes and fees
9.4/10 Exceptional! (839 reviews)
Very enjoyable overall. The one negative item worth mentioning would be the the warmth in one of our rooms. Their AC was not on for the season, as expected. But the room held it's overly warm temperature even with the balcony doors cracked. Not feeling comfortable sleeping with the doors open it ...
Reviewed on Mar 12, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in South Eastern Region
Malta Experience
Enjoy a show at Malta Experience, a storied theater in Valletta. Stroll along the area's seaside, or simply savor its top-notch restaurants.
St. Johns Co - Cathedral
After visiting St. Johns Co - Cathedral, make a plan to see the other sights and activities in Valletta. Wander the area's seaside or simply enjoy one of its top-notch restaurants.
Upper Barrakka Gardens
Perched above Valletta's Grand Harbour is an exquisite park of flowers and statues, from where a cannon salute is fired every day.
What to do in South Eastern Region
Comino Island: including Blue Lagoon, Crystal Lagoon & sea caves
$35
per adult
80% of travellers recommend
Valletta: Guided Walking Tour with Optional Cathedral Tour
$45
per adult
Malta National Aquarium Entrance Ticket
$20
per adult
92% of travellers recommend
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