South Eastern Region Vacations from $1,041

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Your South Eastern Region Vacation

With a South Eastern Region vacation package, you can forget about the stress of planning and just focus on experiencing all this lively destination has on offer. You'll have a long to-do list during your trip to South Eastern Region. One top city you'll want to explore is Valletta. Expedia has flights, hotels and everything else you need to help you create your own customized South Eastern Region vacation today.

The Latest South Eastern Region vacation packages

Price found within the past 48 hours. Click for updated prices.
Antoniel Suites

Antoniel Suites

Paceville
$1,041
per person
Nov 25 - Nov 27
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Luqa (MLA)
9/10 Wonderful! (51 reviews)
St Julian's Bay Hotel

St Julian's Bay Hotel

Il-Balluta
$1,052
per person
Nov 25 - Nov 27
found 9 hours ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Luqa (MLA)
6.8/10 (1,001 reviews)
The Londoner Hotel St. Julians

The Londoner Hotel St. Julians

Paceville
$1,064
per person
Nov 25 - Nov 27
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Luqa (MLA)
8.8/10 Excellent! (244 reviews)
Cleaning service was good but twice they left out changing out towels and toilet paper. I did request and they did give it to me promptly which I appreciate.

Reviewed on Oct 21, 2026

Belle Boutique

Belle Boutique

$1,071
per person
Nov 25 - Nov 27
found 9 hours ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Luqa (MLA)
8.8/10 Excellent! (91 reviews)
Being situated in a street level room was quite noisy until late into the night and there did not appear to be any sound proofing of the window. It was also very noisy with people coming in and out of the hotel as everyone passed our room and we were next to the entry door. Overall the room and building were nice, purely the issue with noise for us. Breakfast looked very basic but as we had to get to airport we didn’t have time to eat breakfast.

Reviewed on Oct 12, 2026

Water's Edge

Water's Edge

$1,075
per person
Nov 25 - Nov 27
found 9 hours ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Luqa (MLA)
8.4/10 Very Good! (336 reviews)
Niice place

Reviewed on Oct 18, 2026

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Where to stay in South Eastern Region

Find the best South Eastern Region areas and neighborhoods for the activities you enjoy most. Learn more about South Eastern Region
A rocky coastal path with clear blue sea and sparse vegetation.

San Tumas

When in San Tumas, you can plan a visit to St. Peter's Pool and Pretty Bay, some noteworthy sights in the nearby area.

A coastal landscape with a rocky outcrop, clear blue sea, and a distant cityscape.

Bellavista

While Bellavista might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Marsaxlokk Bay and Grand Harbour.

A stone building with green doors and a staircase leading up to it.

Misraħ Strejnu

While there might not be top attractions in Misraħ Strejnu, you can explore the larger area and discover places like Marsaxlokk Bay and St. Peter's Pool.

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Il-Ħerba

While Il-Ħerba might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Marsaxlokk Bay and Hal Saflieni Hypogeum.

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Tal-Plier

While Tal-Plier might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Grand Harbour and Inquisitor's Palace.

Stay near popular South Eastern Region attractions

An aerial view of a coastal city with dense urban architecture, a prominent church, and a marina filled with boats.

Malta Experience

8.8/10 (1,972 reviews)
Enjoy a show at Malta Experience, a storied theater in Valletta. Stroll along the area's seaside, or simply savor its top-notch restaurants.
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A stone bridge with arches and people sitting on benches.

Upper Barrakka Gardens

9.0/10 (1,783 reviews)
Perched above Valletta's Grand Harbour is an exquisite park of flowers and statues, from where a cannon salute is fired every day.
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An ornate altar with a large chandelier, golden decorations, and a detailed ceiling fresco.
Photo by Robby Delaware

St. Johns Co - Cathedral

9.4/10 (738 reviews)
After visiting St. Johns Co - Cathedral, make a plan to see the other sights and activities in Valletta. Wander the area's seaside or simply enjoy one of its top-notch restaurants.
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An aerial view of a fortified city with a prominent castle, a harbor, and surrounding urban area.

Fort St. Elmo

8.8/10 (1,361 reviews)
This battle-scared fortress has stood watch over Malta’s capital city for more than 400 hundred years. Learn about the historic sieges that took place here through dramatic reenactments.
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A waterfront promenade at night with illuminated buildings and a boat docked by the water.
Photo by Rosmarie Danz

The Valletta Waterfront

9.4/10 (144 reviews)
After visiting The Valletta Waterfront, make a plan to see the other sights and activities in Floriana. Stroll along the seaside in this family-friendly area, or check out its lively bars.
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A street with parked cars and people walking. There is a banner hanging from a building that reads "Casa Rocca Piccola 16th Century Palazzo Open".

Casa Rocca Piccola

9.0/10 (69 reviews)
Get a glimpse into the lives of an aristocratic Maltese family when you tour this 16th-century palace.
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Mediterranean Conference Centre

8.2/10 (138 reviews)
Mediterranean Conference Centre is just one of the places to see in Valletta, so why not enjoy the other things to explore during your travels? Wander the area's seaside or simply enjoy one of its top-notch restaurants.
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City Gate

10.0/10 (1 review)
Find out about the history of Valletta when you spend time at City Gate. While you're in the area, stroll along the waterfront.
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What to do in South Eastern Region

Malta: Gozo & Comino Islands, Blue Lagoon & Seacaves Tour

Malta: Gozo & Comino Islands, Blue Lagoon & Seacaves Tour

$37
per adult
88% of travellers recommend
Malta: Gozo & Comino Islands, Blue Lagoon & Seacaves Tour
Comino: Blue Lagoon, Crystal Lagoon, and Seacaves Tour

Comino: Blue Lagoon, Crystal Lagoon, and Seacaves Tour

$34
per adult
90% of travellers recommend
Comino: Blue Lagoon, Crystal Lagoon, and Seacaves Tour
Malta Boat: Comino Blue Lagoon,Crystal Lagoon, Gozo & Caves

Malta Boat: Comino Blue Lagoon, Crystal Lagoon, Gozo & Caves

$40
per adult
98% of travellers recommend
Malta Boat: Comino Blue Lagoon, Crystal Lagoon, Gozo & Caves
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South Eastern Region Hotel Deals

Grand Hotel Excelsior

Grand Hotel Excelsior

Great Siege Road Floriana Malta
Fully refundableReserve now, pay when you stay
$152 nightly
$166 total
Nov 23 - Nov 24
Total with taxes and fees
8.8/10 Excellent! (1,007 reviews)
"We love the Grand Excelsior and have stayed many times. It is a little tired and closing shortly for a significant extension and refurbishment. We look forward to revisiting in September 2028 when our favourite hotel reopens."

Reviewed on Oct 22, 2026

Grand Hotel Excelsior
The Phoenicia Malta - The Leading Hotels of the World

The Phoenicia Malta - The Leading Hotels of the World

The Mall Floriana Malta
Fully refundableReserve now, pay when you stay
$412 nightly
$444 total
Nov 16 - Nov 17
Total with taxes and fees
9.4/10 Exceptional! (1,000 reviews)
"All - Really all !! Of the staff has understood why they are there and what their individual contribution to customer satisfaction is. A true gem."

Reviewed on Oct 19, 2026

The Phoenicia Malta - The Leading Hotels of the World
Tritoni Valletta Boutique Hotel

Tritoni Valletta Boutique Hotel

33 Triq Vincenzo Dimech Floriana
Fully refundableReserve now, pay when you stay
$96 nightly
$106 total
Nov 16 - Nov 17
Total with taxes and fees
Tritoni Valletta Boutique Hotel
See all 1,047 properties in South Eastern Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best South Eastern Region Vacation Packages

South Eastern Region Essential Information

Language
Maltese
Currency
Euros
Local Welcome
Hawn
Local Goodbye
Ċaw
Top Sights
Upper Barrakka Gardens, Lower Barrakka Gardens and Marsaxlokk Bay

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.