South End Vacations from $727

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Your South End Vacation

Culture, dining, food, fun — you'll find all that and more in South End. Experience the best of this neighborhood with a vacation package to South End. Not sure what to do and see during your trip to South End? Nearby attractions such as Fenway Park, Boston Common and Faneuil Hall Marketplace are great places to start. Expedia will help put your plans into action. Book your dream South End vacation today.

The Latest South End Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Battery Wharf Hotel, Boston Waterfront

Battery Wharf Hotel, Boston Waterfront

North End
Save 100% on your flight
$727
per person
Nov 20 - Nov 24
found 11 hours ago
Roundtrip non-stop flight included
Burbank (BUR) to Boston (BOS)
9/10 Wonderful! (2,041 reviews)
Four Seasons Hotel Boston

Four Seasons Hotel Boston

Bay Village
Save 100% on your flight
$1,148
per person
Dec 15 - Dec 18
found 16 hours ago
Roundtrip flight included
Los Angeles (LAX) to Boston (BOS)
9.4/10 Exceptional! (487 reviews)
Your staff is Five star! Hotel needs updating badly. My far the worst Four Seasons we have stayed in. On the day of check-in, our flight was delayed and we got in at 2:30 in the morning had room service and it was an edible. Your staff indicated they would remove the charges, but I see we were still charged for them as well.

Reviewed on Oct 6, 2026

Boston Harbor Hotel

Boston Harbor Hotel

North End
Save 100% on your flight
$1,049
per person
Dec 26 - Dec 29
found 1 day ago
Roundtrip non-stop flight included
Burbank (BUR) to Boston (BOS)
9.8/10 Exceptional! (1,008 reviews)
Mandarin Oriental, Boston

Mandarin Oriental, Boston

Back Bay
Save 100% on your flight
$1,124
per person
Dec 15 - Dec 18
found 16 hours ago
Roundtrip flight included
Los Angeles (LAX) to Boston (BOS)
9.4/10 Exceptional! (458 reviews)
Raffles Boston

Raffles Boston

Back Bay
$1,204
per person
Dec 26 - Dec 29
found 2 hours ago
Roundtrip non-stop flight included
Burbank (BUR) to Boston (BOS)
9.6/10 Exceptional! (332 reviews)

Where to stay in South End

Find the best South End areas and neighborhoods for the activities you enjoy most. Learn more about South End
A nighttime street scene with illuminated trees, a market stall, and historic buildings.

Downtown Boston

Densely packed with highrise buildings, this area boasts landmarks like Custom House Tower and is close to Quincy Market, Faneuil Hall, and the Old State House. Find headquarters of major banks, hotels, and investment firms here.

A historic building with ornate architecture, a staircase, and a tree in front.

Back Bay

1 out of top 10 points of interest in this area

Victorian brownstone homes and cultural institutions like the Boston Public Library define this area. Shop at Newbury Street, Prudential Center, and Copley Place, or explore sights like Trinity Church and the John Hancock Tower.

A city skyline with modern high-rise buildings, a historic bridge, and a river with boats.

Seaport District

1 out of top 10 points of interest in this area

Experience a transformed industrial area with office towers, innovation labs, and 78 restaurants. Visit the Institute of Contemporary Art and easily access Downtown Boston via the Evelyn Moakley Bridge.

A street lamp with a lit bulb, surrounded by trees and a brick building.

Beacon Hill

1 out of top 10 points of interest in this area

Historic Federal-style rowhouses, gaslit streets, and brick sidewalks create a charming atmosphere. Explore the Boston African American National Historic Site, shop on Charles Street, and easily access MBTA stations.

A bustling riverside area with a prominent building featuring a large arched entrance, a dock with a boat, and a crowd of people.

North End

Indulge in Italian cuisine at numerous restaurants and bakeries, explore historic sites like Old North Church and Paul Revere House, and enjoy performances at NEMPAC and Improv Asylum Theater. Easily accessible via MBTA lines, buses, and ferries.

South End Hotel Deals

The Revolution Hotel

The Revolution Hotel

40 Berkeley Street Boston MA
Fully refundableReserve now, pay when you stay
$143 nightly
$167 total
Nov 1 - Nov 2
Total with taxes and fees
9/10 Wonderful! (2,969 reviews)
"The decor of the hotel lobby and room set up was very unique.The room and bathrooms were extremely clean. I used the shared bathroom and it was always well maintained. I would stay here again."

Reviewed on Oct 12, 2026

The Revolution Hotel
Hampton Inn & Suites Boston Crosstown Center

Hampton Inn & Suites Boston Crosstown Center

811 Massachusetts Ave Boston MA
Fully refundableReserve now, pay when you stay
$118 nightly
$138 total
Nov 9 - Nov 10
Total with taxes and fees
Hampton Inn & Suites Boston Crosstown Center
Residence Inn by Marriott Boston Downtown / South End

Residence Inn by Marriott Boston Downtown / South End

2001 Washington Street Boston MA
Fully refundableReserve now, pay when you stay
$204 nightly
$238 total
Nov 1 - Nov 2
Total with taxes and fees
Residence Inn by Marriott Boston Downtown / South End
See all 4,072 properties in South End
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular South End attractions

Cathedral of the Holy Cross

Cathedral of the Holy Cross is just one of the places to see in Boston, so why not enjoy the other things to explore during your travels? Experience the fascinating museums and acclaimed theater scene in this vibrant area.
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SoWa Artists Guild

You can study the exhibits at SoWa Artists Guild, a museum with a story of its own, during your trip to Boston. Experience the acclaimed theater scene or attend a sporting event in this vibrant area.
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Calderwood Pavilion

8.0/10 (1 review)
You can get tickets for a performance at Calderwood Pavilion during your trip to Boston. Discover the cafes and entertainment venues in this walkable area.
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Mills Gallery

You can study the exhibits at Mills Gallery, a museum with a story of its own, during your travels to Boston. Experience the acclaimed theater scene or attend a sporting event in this vibrant area.
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SoWa Power Station

After visiting SoWa Power Station, make a plan to see the other sights and activities in Boston. Discover the cafes and entertainment venues in this walkable area.
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Asa Phillip Randolph Memorial

You can learn about the history of Boston with a visit to Asa Phillip Randolph Memorial.
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Alpha Gallery

You can study the exhibits at Alpha Gallery, a museum with a storied past, during your travels to Boston. Experience the acclaimed theater scene or attend a sporting event in this vibrant area.
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Boston Center for the Arts

Enjoy an outing to Boston Center for the Arts during your stay in Boston. Discover the cafes and entertainment venues in this walkable area.
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Things to do

Ghosts and Gravestones Tour guides in costume in Boston

Boston Haunted Tour : Ghosts & Gravestones

$46
per adult
80% of travellers recommend
Boston Haunted Tour : Ghosts & Gravestones
Boston Harbor Cruise boat with the skyscrapers of the city in the background in Boston

City Cruises Boston: Historic Sightseeing Cruise

$37
per adult
92% of travellers recommend
City Cruises Boston: Historic Sightseeing Cruise
Liberty Star

Classic Tall Ship Cruise in Boston Harbor

$40
per adult
94% of travellers recommend
Classic Tall Ship Cruise in Boston Harbor
See all activities in Boston
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.