Photo by Karen Leone

Search Guest Houses in South San Diego

Start date: Check-in selected.
To Date
End date: Check-out

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

Next weekend
Dec 12 - Dec 14
In two weeks
Dec 19 - Dec 21
In one month
Jan 2 - Jan 4
In two months
Jan 30 - Feb 1

Guest Houses in South San Diego

Miscellaneous
El Primero Hotel

El Primero Hotel

2.5 star property
Downtown Chula Vista
9.2 out of 10, Wonderful, (1000)
"Well maintained and the staff are great."
United States
Junzky
$94 nightly
The price is $103
Dec 3 - Dec 4
Total with taxes and fees
El Primero Hotel
BBQ/picnic area
Vineyard Hacienda

Vineyard Hacienda

3.5 star property
Spring Valley
9.2 out of 10, Wonderful, (535)
"Great room. Fun staff"
United States
Patricia
$167 nightly
The price is $181
Dec 10 - Dec 11
Total with taxes and fees
Vineyard Hacienda
Fridge, coffee/tea maker, cookware/dishes/utensils
Heart of SD | Zoo Nearby | Private Patio | Central

Heart of SD | Zoo Nearby | Private Patio | Central

Mid-City
8.0 out of 10, Very Good, (4)
"Such a cute and perfect spot! Had all the thoughtful touches. Was very cozy, bed was comfy and little patio was great. I would definitely stay here again! "
United States
Tanya R.
$170 nightly
The price is $189
Dec 7 - Dec 8
Total with taxes and fees
Heart of SD | Zoo Nearby | Private Patio | Central
Exterior
Garden Cottage | 200Mbps | Sofabed | 55”TV | Patio

Garden Cottage | 200Mbps | Sofabed | 55”TV | Patio

University City
10.0 out of 10, Exceptional, (1)
"Great place,near my son so was perfect"
United States
noel o.
$295 nightly
The price is $328
Dec 8 - Dec 9
Total with taxes and fees
Garden Cottage | 200Mbps | Sofabed | 55”TV | Patio
Fridge, microwave, oven, stovetop
Newly Built Guest Home

Newly Built Guest Home

Mira Mesa
10.0 out of 10, Exceptional, (35)
"Very modern place and convince to all the stores. "
United States
Alberta C.
$533 nightly
The price is $592
Dec 16 - Dec 17
Total with taxes and fees
Newly Built Guest Home
Property grounds
Rockaway North - Family Friendly, Garage Parking & Laundry

Rockaway North - Family Friendly, Garage Parking & Laundry

Mission Beach
9.8 out of 10, Exceptional, (26)
"It was the perfect little getaway for our family. The apartment apartment is small but very efficient and the property managers were awesome about their communication with us as we were checking in and getting stuff for our kids. We really appreciate it. The effort that the owners put into the space the bed was comfortable. The shower was awesome. Appliances and cookware new and ready to use. And best of all just steps from the beach as advertised. We would would happily return and hope that...
United States
Alexander C.
$367 nightly
The price is $401
Dec 15 - Dec 16
Total with taxes and fees
Rockaway North - Family Friendly, Garage Parking & Laundry
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Black Friday Sale

Limited-time deals: Save up to 50% on select hotels.
Book now
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top South San Diego Hotel Reviews

Wyndham San Diego Bayside

Wyndham San Diego Bayside

10/10 Excellent
"The rooms are spacious and well kept. The staff is friendly, courteous, and helpful. Favorite part of staying here is the location. Fantastic bay view, great parking and easy to get in and out of it. It’s walking distance to little Italy and to the Metro if you wish to leave your car and visit Old Town. "
Patricia 1-night trip
Posted 13 hours ago
Wyndham San Diego Bayside

Find out more about South San Diego

South San Diego Guest Houses information

Number of reviews
1,539
Accommodation
18 Guest Houses
Lowest Price
$103
Highest Price
$592

Frequently asked questions

What is the nightly rate for a guest house in South San Diego?
Rates for South San Diego guest houses vary, but travelers can find great-value prices from $103 with Expedia. A range of factors can affect nightly rates, such as the location, the breakfast offering, and the range of amenities. Travelers looking for a good deal should consider looking for a midweek stay, as weekend rates at South San Diego guest houses tend to be higher. Remember to also use our filters to sort prices from low to high.
What's the difference between a South San Diego guest house and a B&B?
A guest house in South San Diego is typically a larger establishment with more rooms, offering a more hotel-like experience, and may provide additional amenities including luxury bedding. In contrast, a B&B is usually a smaller property that focuses primarily on providing a room and breakfast. A B&B is often more personal, and breakfast is typically included as part of the stay, but other services might be more limited compared to a guest house.

Explore a world of travel with Expedia