Southeast Houston Vacations from $155

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Your Southeast Houston Vacation

Take the fuss out of planning your next adventure by booking a Southeast Houston vacation package. Immerse yourself in the sights and sounds of this appealing neighborhood and experience everything it has to offer. When the time comes to sightsee during your trip to Southeast Houston, don't miss nearby attractions such as 1940 Air Terminal Museum. Expedia will help put your plans into action. Book your ultimate Southeast Houston vacation now.

The Latest Southeast Houston Vacation Packages

Price found within the past 48 hours. Click for updated prices.
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hotel Saint Augustine
Margaritaville Lake Resort, Lake Conroe/Houston
Experience a First Class Stay - 2 BDRM
Hilton Houston Post Oak by the Galleria

Where to stay in Southeast Houston

Find the best Southeast Houston areas and neighborhoods for the activities you enjoy most. Learn more about Southeast Houston

Southeast Houston Hotel Deals

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street, Houston, TX
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $125 total per night from Nov 27 to Nov 28
$125 total
Nov 27 - Nov 28
Total with taxes and fees
8.2/10 Very Good! (444 reviews)
Great service

Reviewed on Oct 26, 2025

DoubleTree by Hilton Houston Medical Center Hotel & Suites
Houston Marriott South at Hobby Airport

Houston Marriott South at Hobby Airport

3.5 out of 5
9100 Gulf Fwy, Houston, TX
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Nov 21 to Nov 22
$110 total
Nov 21 - Nov 22
Total with taxes and fees
8.6/10 Excellent! (1,289 reviews)
Great customer service and very professional staff. Very convenient area to site see and get to the airport in a timely manner

Reviewed on Oct 28, 2025

Houston Marriott South at Hobby Airport
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD, Houston, TX
Fully refundableReserve now, pay when you stay
$173 nightly
The price is $201 total per night from Nov 29 to Nov 30
$201 total
Nov 29 - Nov 30
Total with taxes and fees
9/10 Wonderful! (1,028 reviews)
Yes

Reviewed on Nov 4, 2025

The Westin Houston Medical Center/Museum District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Southeast Houston

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.