Southeast Houston Vacations from $221

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Your Southeast Houston Vacation

Take the fuss out of planning your next adventure by booking a Southeast Houston vacation package. Immerse yourself in the sights and sounds of this appealing neighborhood and experience everything it has to offer. When the time comes to sightsee during your trip to Southeast Houston, don't miss nearby attractions such as 1940 Air Terminal Museum. Expedia will help put your plans into action. Book your ultimate Southeast Houston vacation now.

The Latest Southeast Houston Vacation Packages

Price found within the past 48 hours. Click for updated prices.
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
Greater Uptown
Save 100% on your flight
Price was $352, price is now $221 per person
$221
per person
Jan 22 - Jan 25
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.2/10 Very Good! (2,889 reviews)
Awesome stay, polite and expedient staff.

Reviewed on Dec 21, 2025

Reside Houston Dwntwn, Wyndham

Reside Houston Dwntwn, Wyndham

3.5 out of 5
Downtown Houston
Save 100% on your flight
Price was $1,045, price is now $599 per person
$599
per person
Mar 9 - Mar 14
found 18 hours ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.6/10 Excellent! (832 reviews)
Clean rooms, very nice front desk staff.

Reviewed on Dec 12, 2025

Margaritaville Lake Resort, Lake Conroe/Houston

Margaritaville Lake Resort, Lake Conroe/Houston

3.5 out of 5
Save 100% on your flight
Price was $993, price is now $611 per person
$611
per person
Jan 28 - Feb 1
found 24 hours ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.2/10 Very Good! (1,006 reviews)
No free breakfast, no microwave (rediculous), very hard to find light switches for lamps, no wifii, parking far from entrance altho shuttle was helpful. Beautiful sunrise and sunset…..oh wait…God made those.

Reviewed on Dec 4, 2025

Hotel Granduca Houston

Hotel Granduca Houston

4 out of 5
The Galleria
Save 100% on your flight
Price was $1,201, price is now $741 per person
$741
per person
Feb 27 - Mar 2
found 23 hours ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9.2/10 Wonderful! (1,002 reviews)
This is literally one of the Best Hotel I have stayed at. I loved everything about it. I would highly recommend it. I was there with friends celebrating my birthday. Everyone had an amazing time…

Reviewed on Dec 18, 2025

ECLIPZ Modern CEO Corp House

ECLIPZ Modern CEO Corp House

5 out of 5
Save 100% on your flight
Price was $3,633, price is now $2,351 per person
$2,351
per person
Mar 10 - Mar 16
found 1 day ago
Roundtrip non-stop flight included
New York (LGA) to Houston (IAH)
No reviews

Where to stay in Southeast Houston

Find the best Southeast Houston areas and neighborhoods for the activities you enjoy most. Learn more about Southeast Houston
Discovery Green which includes a city, central business district and a high rise building

Downtown Houston

3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

Find hotels in Downtown Houston

Southeast Houston Hotel Deals

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $189 total per night from Dec 23 to Dec 24
$189 total
Dec 23 - Dec 24
Total with taxes and fees
9/10 Wonderful! (1,025 reviews)
Service

Reviewed on Dec 20, 2025

The Westin Houston Medical Center/Museum District
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street Houston TX
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $139 total per night from Dec 27 to Dec 28
$139 total
Dec 27 - Dec 28
Total with taxes and fees
8.2/10 Very Good! (476 reviews)
The room was very clean and the staff was friendly. I wish there was a microwave in the room and the bathroom could’ve been larger but other than that my stay was wonderful.

Reviewed on Dec 14, 2025

DoubleTree by Hilton Houston Medical Center Hotel & Suites
Houston Marriott South at Hobby Airport

Houston Marriott South at Hobby Airport

3.5 out of 5
9100 Gulf Fwy Houston TX
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $100 total per night from Dec 26 to Dec 27
$100 total
Dec 26 - Dec 27
Total with taxes and fees
8.8/10 Excellent! (1,329 reviews)
Yes

Reviewed on Dec 20, 2025

Houston Marriott South at Hobby Airport
See all 1,159 properties in Southeast Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Southeast Houston

University of Houston

University of Houston

4/5(392 reviews)

Enjoy the collegiate vibe when you visit University of Houston, during your travels in Houston. Experience the acclaimed art scene and lively festivals in this vibrant area.

University of Houston
Houston Zoo

Houston Zoo

4.5/5(998 reviews)

Feed a giraffe, catch a 4-D movie or cool off in the water park at this extraordinary zoo.

Houston Zoo
Houston Natural Science Museum featuring heritage elements and interior views

Houston Natural Science Museum

4.5/5(805 reviews)

You can spend time studying the exhibits at Houston Natural Science Museum in Houston. Experience the area's lively festivals and entertainment choices.

Houston Natural Science Museum

Things to do

Houston: Houston Botanic Garden Entry Ticket

Houston: Houston Botanic Garden Entry Ticket

$12
per adult
80% of travellers recommend
Houston: Houston Botanic Garden Entry Ticket
Houston: Museum of Natural Science General Admission Ticket

Houston Museum of Natural Science General Admission Ticket

$25
per adult
96% of travellers recommend
Houston Museum of Natural Science General Admission Ticket
Houston Museum of Natural Science: Cockrell Butterfly Center

Houston Museum of Natural Science: Cockrell Butterfly Center

$15
per adult
100% of travellers recommend
Houston Museum of Natural Science: Cockrell Butterfly Center
See all activities in Houston
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.