Photo by Bill Dillard

Find Historic Hotels in Southeast Missouri, MO

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Our top choices for Southeast Missouri historic hotels

Fridge, microwave, oven, stovetop
⚜️Rivertown Retreat⚜️ Lewis & Clark stayed here. King bed. Sleeps 4

⚜️Rivertown Retreat⚜️ Lewis & Clark stayed here. King bed. Sleeps 4

2.0 star property
Ste. Genevieve
10.0 out of 10, Exceptional, (18)
"Great historic property!"
United States
Rhonda R.
$206 nightly
The price is $206
Dec 13 - Dec 14
Total with taxes and fees
⚜️Rivertown Retreat⚜️ Lewis & Clark stayed here. King bed. Sleeps 4
1 bedroom, iron/ironing board, bed sheets
Beautiful Modern Loft In Wine Country!

Beautiful Modern Loft In Wine Country!

Ste. Genevieve
10.0 out of 10, Exceptional, (271)
"Loved our stay here! Thoughtful amenities on a beautiful property. Great communication with host. "
United States
Elsie H.
$169 nightly
The price is $180
Dec 12 - Dec 13
Total with taxes and fees
Beautiful Modern Loft In Wine Country!
Property grounds
The Weber Farm - Enjoy a beautiful 100 acre farm!

The Weber Farm - Enjoy a beautiful 100 acre farm!

Frohna
10.0 out of 10, Exceptional, (32)
"Hosts were great. I just wish they had a second bath or atleast a larger bathroom. "
United States
Dennis H.
$178 nightly
The price is $184
Dec 10 - Dec 11
Total with taxes and fees
The Weber Farm - Enjoy a beautiful 100 acre farm!
Exterior detail
"Little Brick House on Main (1865)”

"Little Brick House on Main (1865)”

Ste. Genevieve
10.0 out of 10, Exceptional, (63)
"Great place to stay!"
United States
Lettitia B.
$159 nightly
The price is $159
Dec 17 - Dec 18
Total with taxes and fees
"Little Brick House on Main (1865)”
Fridge, microwave, oven, stovetop
Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space

Cape Girardeau
10.0 out of 10, Exceptional, (148)
"Such a great place and location"
United States
Tracy H.
$229 nightly
The price is $245
Dec 10 - Dec 11
Total with taxes and fees
Serenity South -- Gardens, River-Views, and Refreshing Space
Property grounds
Country Inn Motel

Country Inn Motel

2.0 star property
Licking
7.2 out of 10, Good, (330)
"Friendly staff and clean room"
United States
Peggy
$55 nightly
The price is $60
Dec 10 - Dec 11
Total with taxes and fees
Country Inn Motel
Exterior
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Anna
10.0 out of 10, Exceptional, (403)
"Very clean, courteus staff. Beautiful area and quiet. Very relaxing."
United States
Tommy
$189 nightly
The price is $200
Dec 11 - Dec 12
Total with taxes and fees
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Exterior
Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre

Dongola
10.0 out of 10, Exceptional, (101)
"Location was great, everything was great for what we were there for. Already booked again for November. "
United States
carlton h.
$265 nightly
The price is $281
Dec 10 - Dec 11
Total with taxes and fees
Charming cottage overlooking Lake Acre
Property grounds
Peter Ray House

Peter Ray House

Maeystown
10.0 out of 10, Exceptional, (70)
"The house was wonderful, the town was delightful, and the people were very friendly! We can’t wait for our next trip!"
United States
Deborah
$211 nightly
The price is $224
Dec 10 - Dec 11
Total with taxes and fees
Peter Ray House
Fridge, microwave, oven, stovetop
Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

The Hill
9.8 out of 10, Exceptional, (160)
"Very clean, check in was easy, great neighborhood with lots of food close. "
United States
Laura H.
$136 nightly
The price is $139
Dec 10 - Dec 11
Total with taxes and fees
Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotel Reviews

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

10/10 Excellent
"The rooms where clean, the water was hot in the showers. The staff was family oriented and friendly felt like my family was safe."
Joseph 2-night trip
Posted 2 days ago
Baymont Inn and Suites by Wyndham Farmington, MO

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