Name: Hilton Houston Plaza/Medical Center
Price range: $122 total
Rating: 8.2

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Your Southeast Texas Vacation

Lock in a vacation package to Southeast Texas and experience travel on your own terms. You'll be impressed by its nature, dining and history. Kick off your trip to Southeast Texas with a couple of nights in Houston visiting popular attractions like NRG Stadium and MD Anderson Cancer Center. Katy is another city that draws travelers from far and wide. Katy Mills Mall and Typhoon Texas are two of the top places to see here. Expedia has flights, hotels, car rentals and more to help you curate your very own tailored Southeast Texas vacation today.

The Latest Southeast Texas vacation packages

Price found within the past 48 hours. Click for updated prices.

Kompose Residences Houston Cy-Fair

Save 100% on your flight

$248

per person

Mar 26 - Mar 29

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Houston (IAH)

10/10 Exceptional! (2 reviews)

OIVE the uniqueness of the place. Super friendly, staff, very clean, nice breakfast.

Reviewed on Jan 9, 2026

Rusk House Serviced Apartments

Downtown Houston

Save 100% on your flight

$440

per person

Mar 26 - Mar 29

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Houston (IAH)

9.2/10 Wonderful! (296 reviews)

Great staff, nice amenities, super clean. Only minus was the lack of pool, and the sofa bed was uncomfortable. Comfortable as a sofa, but not as a bed.

Reviewed on Jan 8, 2026

Margaritaville Lake Resort, Lake Conroe/Houston

Save 100% on your flight

$669

per person

Mar 26 - Mar 29

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Houston (IAH)

8.2/10 Very Good! (1,006 reviews)

Yes great God bless you all 🙏

Reviewed on Jan 6, 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

Greater Uptown

Save 100% on your flight

$290

per person

Mar 13 - Mar 16

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Houston (IAH)

8.2/10 Very Good! (2,889 reviews)

Great stay for the Nye and New Year

Reviewed on Jan 10, 2026

Blossom Hotel Houston, Curio Collection by Hilton

Texas Medical Center

Save 100% on your flight

$489

per person

Mar 6 - Mar 9

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Houston (IAH)

9/10 Wonderful! (3,554 reviews)

Clean, well appointed room. Welcoming staff. Having a hot tub would make it perfect.

Reviewed on Jan 9, 2026

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Where to stay in Southeast Texas

Find the best Southeast Texas areas and neighborhoods for the activities you enjoy most. Learn more about Southeast Texas

Discovery Green which includes a city, central business district and a high rise building

Downtown Houston

3 out of top 10 points of interest in this area

4.5/5(2,300 area reviews)

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

Texas Medical Center

1 out of top 10 points of interest in this area

4/5(566 area reviews)

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Discover the most popular places to visit in Southeast Texas

Close to the entrance of convention center.

George R. Brown Convention Center

During your trip, find out what's happening at George R. Brown Convention Center, a top convention center in Houston. Experience the great live music and lively festivals in this vibrant area.

Galveston Seawall

You can learn about the local history of Galveston during your trip to a well-known site like Galveston Seawall. Wander the beautiful beaches and seaside in the area.

NASA Johnson Space Center

After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.

Southeast Texas Hotel Deals

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

5353 Westheimer Rd Houston TX

Fully refundableReserve now, pay when you stay

$145 nightly

$169 total

Jan 19 - Jan 20

Total with taxes and fees

8.2/10 Very Good! (3,228 reviews)

Perfect as always!

Reviewed on Jan 6, 2026

Club Quarters Hotel Downtown, Houston

1085 Rusk Street Houston TX

Fully refundableReserve now, pay when you stay

$89 nightly

$104 total

Jan 17 - Jan 18

Total with taxes and fees

8.4/10 Very Good! (3,994 reviews)

I travel to Houston several times in a year. First time staying at Club Quarters Hotel and it may be the best stay for an excellent price. Great service from hotel staff as well as valet, they took really good care of me. Nice view of downtown Houston, perfect spot, not far from restaurants or entertainment ...

Reviewed on Jan 6, 2026

Hilton Houston Plaza/Medical Center

6633 Travis St Houston TX

Fully refundableReserve now, pay when you stay

$104 nightly

$122 total

Jan 22 - Jan 23

Total with taxes and fees

8.2/10 Very Good! (1,814 reviews)

The property was wonderful, but the staff was Exemplary. I spent about 10-12 days here on different reservations and Seymour, at the front desk, was very helpful and attentive to all of my needs. Thank you Seymour!

Reviewed on Jan 5, 2026

See all 19,162 properties in Southeast Texas

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.