Photo by Southernmost Illinois Tourism Bureau

Find pet-friendly hotels in Southern Illinois, IL from $67

Start date: Check-in selected.
To Date
End date: Check-out

Check availability on Southern Illinois Pet-friendly Hotels

Our top choices for Southern Illinois pet-friendly hotels

Drury Inn & Suites Marion

3.0 star property
Marion
9.4 out of 10, Exceptional, (1002)
"Great hotel and very clean "
United States
Jose
$65 nightly
The price is $78
Jan 2 - Jan 3, 2026
Total with taxes and fees
Drury Inn & Suites Marion

SureStay Hotel by Best Western Whittington Rend Lake

2.5 star property
Whittington
8.8 out of 10, Excellent, (903)
"Great place to stay."
United States
Stephen
$72 nightly
The price is $80
Dec 31 - Jan 1, 2026
Total with taxes and fees
SureStay Hotel by Best Western Whittington Rend Lake

Holiday Inn Express Hotel & Suites Marion Northeast by IHG

2.5 star property
Marion
9.0 out of 10, Wonderful, (925)
"yes the room was great and the staff was great! "
United States
Amador
$97 nightly
The price is $116
Jan 9 - Jan 10, 2026
Total with taxes and fees
Holiday Inn Express Hotel & Suites Marion Northeast by IHG

Comfort Suites Mount Vernon

2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1009)
"Rooms have been painted great breakfast close to interstate and restaurants"
United States
Stephen
$109 nightly
The price is $123
Dec 10 - Dec 11
Total with taxes and fees
Comfort Suites Mount Vernon

Drury Plaza Hotel Mt. Vernon

3.0 star property
Mount Vernon
9.6 out of 10, Exceptional, (1567)
"Great place to stay. Check in is easy and the hotel people are very nice."
United States
Duane
$91 nightly
The price is $104
Dec 16 - Dec 17
Total with taxes and fees
Drury Plaza Hotel Mt. Vernon

Laketree Inn And Suites Marion

2.0 star property
Marion
8.0 out of 10, Very Good, (177)
"Neat little Mom and Pop hotel on the edge of Shawnee National Forest. Very few perks, no breakfast or pool, but solid internet and there's a great BBQ place right down the road. We will be back."
United States
Sarah
$66 nightly
The price is $74
Jan 8 - Jan 9, 2026
Total with taxes and fees
Laketree Inn And Suites Marion

Best Western Delta Inn

2.5 star property
Effingham
9.2 out of 10, Wonderful, (1002)
"Clean room, courteous staff, nice amenities."
United States
Richard M
$84 nightly
The price is $94
Jan 6 - Jan 7, 2026
Total with taxes and fees
Best Western Delta Inn

Quality Inn Effingham North

2.5 star property
Effingham
8.4 out of 10, Very Good, (991)
"Very clean room, friendly staff and great breakfast."
United States
Liz
$77 nightly
The price is $85
Dec 15 - Dec 16
Total with taxes and fees
Quality Inn Effingham North

Best Western Plus Centralia Hotel & Suites

2.5 star property
Centralia
9.6 out of 10, Exceptional, (598)
"Very beautiful place to stay "
United States
Valerie
$121 nightly
The price is $135
Jan 1 - Jan 2, 2026
Total with taxes and fees
Best Western Plus Centralia Hotel & Suites

Quality Inn & Suites Vandalia near I-70 and Hwy 51

2.5 star property
Vandalia
8.4 out of 10, Very Good, (1003)
"Awesome place to stay. Clean room, comfortable bed, amenities were accommodating, plenty of restaurants near by to choose from, and near the highway."
United States
Evelyn
$62 nightly
The price is $67
Jan 6 - Jan 7, 2026
Total with taxes and fees
Quality Inn & Suites Vandalia near I-70 and Hwy 51
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Southern Illinois

Discover top Southern Illinois attractions with your pet

Southern Illinois is a paradise for pet owners looking to explore with their furry friends. Start your adventure at the stunning Shawnee National Forest, where you and your dog can hike through scenic trails and marvel at the natural rock formations like the Garden of the Gods. For water-loving pets, the beautiful Crab Orchard Lake offers opportunities for swimming, fishing, and picnicking by the shore. Don’t miss the charming town of Carbondale, where you can stroll through the dog-friendly parks or enjoy a bite at local cafes that welcome pets on their patios. If you're looking for a unique experience, take a wine tour along the Shawnee Hills Wine Trail, many of which allow pets to join as you sample some of the region's finest wines. For a comfortable stay, consider booking a pet-friendly hotel in the vibrant Carbondale area, where you can unwind after a day of exploration. Enjoy spacious rooms, welcoming amenities, and staff who truly understand the needs of traveling pet families, ensuring your trip is as enjoyable as it is adventurous.

Top Southern Illinois Hotel Reviews

Explore a world of travel with Expedia