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Find Resorts & Hotels with Spas in Southwest Oklahoma, OK

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Check availability on Southwest Oklahoma Resorts & Hotels with Spas

Top Southwest Oklahoma Resorts & Hotels with Spas

No exact matches found, but these alternatives could be just right

Recommended hotels in Southwest Oklahoma

AmericInn by Wyndham Sayre

2.5 star property
Sayre
8.6 out of 10, Excellent, (548)
"Amazing...after just booking elsewhere and the hotel was not even open anymore it was so nice to be welcomed with quick,easy,and prompt service."
United States
Amanda
$83 nightly
The price is $95
Jan 9 - Jan 10, 2026
Total with taxes and fees
AmericInn by Wyndham Sayre

La Quinta Inn & Suites by Wyndham Clinton Historic Route 66

3.0 star property
Clinton
9.2 out of 10, Wonderful, (1001)
"I've stayed here several times and would recommend it for the area."
United States
joey
$86 nightly
The price is $98
Dec 25 - Dec 26
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Clinton Historic Route 66

Lucille's Hotel, Restaurant, & Bar

2.5 star property
Weatherford
9.0 out of 10, Wonderful, (468)
"Good staff. The food was good. A great place to stay. I've traveled up and down I-40 for 10 years and it's the best place I found to stay. Will definitely stay again"
United States
James
$100 nightly
The price is $113
Dec 11 - Dec 12
Total with taxes and fees
Lucille's Hotel, Restaurant, & Bar

Home2 Suites by Hilton Weatherford

3.0 star property
Weatherford
9.4 out of 10, Exceptional, (278)
"The room is very spacious. The breakfast was very nice and delicious."
United States
Don
$74 nightly
The price is $84
Dec 21 - Dec 22
Total with taxes and fees
Home2 Suites by Hilton Weatherford

Apache Casino Hotel

3.5 star property
Lawton
9.0 out of 10, Wonderful, (1007)
"Nice room good stay"
United States
Bryce
$89 nightly
The price is $103
Dec 10 - Dec 11
Total with taxes and fees
Apache Casino Hotel

Best Western Plus Executive Residency Elk City

3.0 star property
Elk City
8.6 out of 10, Excellent, (775)
"Room was ok, staff were nice, good breakfast "
United States
Tim
$76 nightly
The price is $87
Jan 2 - Jan 3, 2026
Total with taxes and fees
Best Western Plus Executive Residency Elk City

Sleep Inn & Suites

2.5 star property
Elk City
8.2 out of 10, Very Good, (1001)
"Clean and comfortable at a good price. "
United States
Dean
$64 nightly
The price is $73
Jan 3 - Jan 4, 2026
Total with taxes and fees
Sleep Inn & Suites

Holiday Inn Express & Suites Duncan by IHG

2.5 star property
Duncan
9.2 out of 10, Wonderful, (480)
"The room was very clean, the entire hotel had a very clean/fresh scent, and the front office ladies were very welcoming. I would definitely stay here again. "
United States
Amy Rodriguez
$75 nightly
The price is $85
Jan 2 - Jan 3, 2026
Total with taxes and fees
Holiday Inn Express & Suites Duncan by IHG

Western Motel

2.0 star property
Sayre
7.4 out of 10, Good, (116)
"Staff was courteous and room was clean"
United States
David
$45 nightly
The price is $52
Dec 10 - Dec 11
Total with taxes and fees
Western Motel

Sugar Creek Inn & Suites

2.0 star property
Hinton
8.8 out of 10, Excellent, (160)
"The staff are very friendly and make you feel welcome. "
United States
Teresa
$75 nightly
The price is $86
Dec 10 - Dec 11
Total with taxes and fees
Sugar Creek Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Southwest Oklahoma

Top Southwest Oklahoma attractions for a relaxing vacation

In Southwest Oklahoma, travelers seeking a rejuvenating escape at spa hotels can explore a blend of natural beauty and cultural experiences. Start your journey at the Wichita Mountains Wildlife Refuge, where you can hike scenic trails, spot bison, and soak in the serene landscapes—perfect for unwinding before a luxurious spa treatment. Don't miss the historic town of Medicine Park, known for its charming cobblestone architecture and vibrant arts scene, where you can enjoy local galleries and artisan shops. For a unique experience, visit the nearby Chickasaw Cultural Center to learn about Native American heritage through interactive exhibits and stunning gardens, offering a peaceful retreat to reflect on your day. After a day of exploration, relax at one of the region's upscale hotels like the Riverwind Casino Hotel in Norman, which offers a full-service spa alongside entertainment options for a balanced getaway. Experience attentive guest service and pampering treatments that cater to your every need, making your stay both rejuvenating and memorable.

Top Southwest Oklahoma Hotel Reviews

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