St. Charles Historic District Vacations from $277

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Your St. Charles Historic District Vacation

Lock in one of our vacation packages to St. Charles Historic District and experience the charms of this interesting neighborhood. Especially known for its history, your next awesome adventure starts right here. Your trip to St. Charles Historic District wouldn't be complete without seeing big-name attractions nearby such as Ameristar Casino St. Charles, Historic Main Street and Lindenwood University. Don't just imagine it — take action! Lock in your ultimate St. Charles Historic District vacation with Expedia and enjoy traveling your way.

The Latest St. Charles Historic District Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Save 100% on your flight
per person
Sep 21 - Sep 23
found 11 hours ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
9.2/10 Wonderful! (1,558 reviews)
Very lovely place to stay the night is you are in the St Louis area.

Reviewed on Aug 12, 2025

The Principal Hotel

The Principal Hotel

3.5 out of 5
Save 100% on your flight
per person
Sep 24 - Sep 27
found 1 day ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
9.8/10 Exceptional! (111 reviews)
Love staying here! The staff is very nice & always making sure you have what you need!

Reviewed on Aug 10, 2025

Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
per person
Sep 24 - Sep 27
found 10 hours ago
Roundtrip flight included
Dallas (DAL) to St. Louis (STL)
8.2/10 Very Good! (760 reviews)
I booked online and paid via the app. When I arrived on site they explained they had overbooked and had no rooms available. The staff was amazing and went above and beyond and secured a room at another location. Thank you to the staff for taking care of us.

Reviewed on Jul 26, 2025

Holiday Inn Express & Suites St. Louis West - Fenton by IHG

Holiday Inn Express & Suites St. Louis West - Fenton by IHG

3 out of 5
per person
Sep 24 - Sep 27
found 10 hours ago
Roundtrip flight included
Dallas (DAL) to St. Louis (STL)
8.8/10 Excellent! (1,001 reviews)
great hotel clean and staff was fantasic

Reviewed on Aug 3, 2025

The Cheshire

The Cheshire

4 out of 5
per person
Sep 24 - Sep 27
found 10 hours ago
Roundtrip flight included
Dallas (DAL) to St. Louis (STL)
8.6/10 Excellent! (1,000 reviews)
Bed and pillows where uncomfortable. Room and facilities were dirty. Parking was a joke due to there being 2 restaurants on the property as well so it was hard to find a spot as the hotel and restaurant shared the parking lot and garage but you had to pay to park if you stayed in the hotel.

Reviewed on Aug 3, 2025

Where to stay in St. Charles Historic District

Find the best St. Charles Historic District areas and neighborhoods for the activities you enjoy most. Learn more about St. Charles Historic District
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

3 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis

St. Charles Historic District Hotel Deals

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 out of 5
1190 S Main St, St. Charles, MO
Fully refundable
$105 nightly
The price is $121 total per night from Aug 17 to Aug 18
$121 total
Aug 17 - Aug 18
Total includes taxes and fees
9.4/10 Exceptional! (1,003 reviews)
"This was the best quaint hotel. Beautiful venue"

Reviewed on Aug 9, 2025

Country Inn & Suites by Radisson, St. Charles Historic District
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $143 total per night from Aug 13 to Aug 14
$143 total
Aug 13 - Aug 14
Total includes taxes and fees
8.2/10 Very Good! (2,044 reviews)
"Nice, clean, modern hotel. Good dinner options within hotel and fun coffee shop."

Reviewed on Aug 8, 2025

Hollywood Casino & Hotel St. Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $116 total per night from Aug 17 to Aug 18
$116 total
Aug 17 - Aug 18
Total includes taxes and fees
8.8/10 Excellent! (2,924 reviews)
"It was perfect. It was quiet. It was clean. Everything was amazing. They were even doing renovations and it didn’t affect anything."

Reviewed on Aug 10, 2025

Clayton Plaza Hotel & Extended Stay
See all 1,585 properties in St. Charles Historic District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in St. Charles Historic District

"The first St. Charles Borromeo Church, like this one, was constructed of vertical, hewn logs placed directly in the ground: an architectural style unique to the French in the New World during the 17th and 18th centuries. The church has been rebuilt on its original location. Jesse Francis, a local preservationist with 20 years experience restoring 18th French log buildings, directed the reconstruction. The work was done completely by with period tools in the manner of the 18th century. The church is part of an on-going historical interpretive program based on a re-creation of daily activities in this old French village."

Historic Main Street

You can learn about the history of St. Charles with a trip to Historic Main Street. Check out the shops and top-notch restaurants in this family-friendly area.

Historic Main Street
Busch Stadium

Busch Stadium

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

Busch Stadium
St. Louis Union Station

St. Louis Union Station

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.

St. Louis Union Station

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour

$24
per adult
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
Best of St. Louis Small Group Tour w/ Arch & River Cruise

Best of St. Louis Small Group Tour w/ Arch & River Cruise

$169
per adult
84% of travellers recommend
Best of St. Louis Small Group Tour w/ Arch & River Cruise
St. Louis: Guided Small Group City Tour with River Cruise

St. Louis: Guided Small Group City Tour with River Cruise

$174
per adult
100% of travellers recommend
St. Louis: Guided Small Group City Tour with River Cruise
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.