Title: Top Independent in St. Charles, MN  - Expedia.com

[St. Charles Travel Guide](https://expedia.com/St-Charles.dx183431)[Hotels in St. Charles](https://expedia.com/St-Charles-Hotels.d183431.Travel-Guide-Hotels)[Vacation Rentals in St. Charles](https://expedia.com/St-Charles-Vacation-Rentals.d183431.Travel-Guide-VacationRentals)[Flights to St. Charles](https://expedia.com/Cheap-Flights-To-St-Charles.d183431.Travel-Guide-Flights)[Car Rentals in St. Charles](https://expedia.com/Car-Rentals-In-St-Charles.d183431.Car-Rental-Guide)[St. Charles Vacation Packages](https://expedia.com/St-Charles.d183431.Destination-Travel-Guides)

![St. Charles is a rural Community in South East Minnesota](https://images.trvl-media.com/place/183431/30533b3b-ce9f-42e7-b976-83514176ce7e.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

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[Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=183431&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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## Top St. Charles Hotel Reviews

![Spark by Hilton Rochester South](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/c7dc0b32_y.jpg)

### Spark by Hilton Rochester South

10/10 Excellent

"Quick check in, nice room. Insulation is lacking so be prepared to hear your neighbors. Breakfast has a lot of high carb options, so if you’re looking for a protein breakfast, you’ll likely need to eat offsite. "

[](https://expedia.com/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information)

![Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/edb11216_y.jpg)

### Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10/10 Excellent

"While the room was adequate and cleaner than expected given the age the mattresses had seen better times and were a bit rough but still serviceable. The kitchen appliances while somewhat dated also very clean and worked well. Only downside was the pots and pans to cook with were a little rough. I suggest bring your favorites if you plan on cooking. The restaurant on site was really good and will even bring to your room. Arcade isn’t great so don’t expect the newest but air hockey is solid as is PAC man. Pool was nice our daughter liked it well enough. Didn’t try it out the hot tub out myself but everything was very clean. Another big plus here is the shuttle to hospital. The only real negative we had was the fiasco with billing while they were switching to a new credit card service. The hotel management was quick to help fix and assured us it wouldn’t happen again. It did but was fixed again just took time. "

[](https://expedia.com/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information)

![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3837h2560x3y0-1092e125_y.jpg)

### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

4/10 Poor

"The entire property smelled strongly of chlorine from the pool. That included in our room. My friend had irritated eyes and sinuses from it. I had a bad headache. It's a nice property with a great staff, but something needs to be done about the smell. "

[](https://expedia.com/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information)

![Kahler Inn and Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/41a1c74b_y.jpg)

### Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent

" Very clean, nice breakfast and convenient to the clinic via walking subway. "

[](https://expedia.com/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information)

![Aspen Suites](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/404886d5_y.jpg)

### Aspen Suites

10/10 Excellent

"Great amenities"

[](https://expedia.com/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information)

![Hyatt House Rochester/Mayo Clinic Area](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/369065b1_y.jpg)

### Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent

"Clean room and helpful, friendly staff! "

[](https://expedia.com/Rochester-Hotels-Hyatt-House-RochesterMayo-Clinic.h56833067.Hotel-Information)

![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/1062bbaa_y.jpg)

### Kahler Grand Hotel

6/10 Okay

"For the price parking should be cheaper and breakfast should be free, especially since most people are staying here for medical reasons"

[](https://expedia.com/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information)

![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/abb2c83e_y.jpg)

### Brentwood Inn & Suites

8/10 Good

"Pillows were too flat. Only had 3 small pillows 4 would have been nice "

[](https://expedia.com/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information)

![Home2 Suites by Hilton Rochester Mayo Clinic Area](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/444e106b_y.jpg)

### Home2 Suites by Hilton Rochester Mayo Clinic Area

2/10 Terrible

"The air conditioner let in air from outside. Thwre was a breeze about 10 mph and it blew in theoughb the ac and whistled all night long no sleep"

[](https://expedia.com/Rochester-Hotels-Home2-Suites-By-Hilton-Rochester-Mayo-Clinic-Area.h23512633.Hotel-Information)

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