Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured St. Charles Red Roof Inn Hotels

See all 268 Hotels in St. Charles
Red Roof Inn St Louis - Westport

Red Roof Inn St Louis - Westport

11837 Lackland Rd, Maryland Heights
2.0 out of 5.0
3.3 out of 5 (1,204 reviews)
If useing a GPS use the adress for HOOTERS WESPORT We had a GPS, it took us to wrong location...... 45 minutes away from the hotel! - 

$49

$49
Red Roof Plus St. Louis - Forest Park / Hampton Ave.

Red Roof Plus St. Louis - Forest Park / Hampton Ave.

5823 Wilson Avenue, St. Louis
2.5 out of 5.0
3.4 out of 5 (1,414 reviews)
Adequate hotel on the Hill for visiting family Just slept there. Very small room would hardly accommodate most travelers with luggage. But if comp … - 

$63

$63
Red Roof Inn St Louis - St Charles

Red Roof Inn St Louis - St Charles

2010 Zumbehl Rd, St. Charles
2.5 out of 5.0
2.9 out of 5 (558 reviews)
A pleasant experience. I wasn't expecting a five star treatment or accommodation so this place fits the bill perfectly. Sp … - 

$50

$50
Map

Recently booked St. Charles hotels

Ameristar Casino Resort and Spa
5.0 out of 5.0
Last booking: 1 hour ago
Country Inn & Suites By Carlson, St. Charles, MO
3.0 out of 5.0
Last booking: 3 hours ago
Holiday Inn Express Hotel and Suites St. Charles
3.5 out of 5.0
Last booking: 4 hours ago
Sleep Inn & Suites
3.0 out of 5.0
Last booking: 8 hours ago
Comfort Suites St Charles-St Louis
3.0 out of 5.0
Last booking: 10 hours ago
Best Western Plus The Charles Hotel
3.0 out of 5.0
Last booking: 12 hours ago
Wingate by Wyndham St. Charles MO
3.5 out of 5.0
Last booking: 13 hours ago
Embassy Suites St. Louis - St. Charles
4.0 out of 5.0
Last booking: 24 hours ago
Towneplace Suites By Marriott St Charles
3.0 out of 5.0
Last booking: 32 hours ago

Pocket Guide: Red Roof Inn Hotels in St. Charles

Search for hotels in St. Charles on Expedia. You can easily find your hotels in St. Charles using one of the methods below:

  • View our selection of featured hotels in St. Charles
  • Use the map to find hotels in the St. Charles neighborhood you prefer
  • Use the filters to see hotels in a specific area of St. Charles, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in St. Charles
  • Enter your travel dates to view the best deals on hotels in St. Charles - while they last