Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.

Featured St. Clairsville Luxury Hotels

See all 82 Hotels in St. Clairsville
Americas Best Value Inn St. Clairsville/Wheeling

Americas Best Value Inn St. Clairsville/Wheeling

51260 National Road East, St. Clairsville
2.5 out of 5.0
4.2 out of 5 (160 reviews)
Staff was excellent the only suggestion I have is maybe have a more comfortable bed for the cot it felt like the springs were coming through the mattress and the breakfast bar could use a little more than waffles and pastry’s!
  Dec 17, 2017


Days Inn Wheeling West

Days Inn Wheeling West

52601 Holiday Dr, St. Clairsville
2.5 out of 5.0
3.7 out of 5 (534 reviews)
Hotel close to highwayStay was comfortable. The hotel is close to highway.
  Sep 5, 2017



Recently booked Luxury Hotels in St. Clairsville

Hampton Inn Wheeling/St. Clairsville
3.5 out of 5.0
Last booking: 3 hours ago
Red Roof Inn St Clairsville - Wheeling West
2.5 out of 5.0
Last booking: 19 hours ago
Comfort Inn
3.0 out of 5.0
Last booking: 24 hours ago
Sleep Inn & Suites Belmont / St. Clairsville
3.0 out of 5.0
Last booking: 30 hours ago

A weekend away keeps your stress at bay, especially when you're visiting St. Clairsville. Scrumptious eats, fascinating sites, and chances to capture phenomenal snapshots: these are just a few of the things you'll love about in St. Clairsville. Of course, you'll stay at a luxury hotel! Sampling the finer things in life is just your speed. While you're here, you'll also grab tickets to the most exciting shows, treat yourself to decadent meals, and eye-guzzle the most noteworthy monuments and landmarks . Book your elegant hotel in St. Clairsville on right now and start your excursion off on the right (well-dressed) foot.

5-Star Vacations in St. Clairsville

If you need any proof that St. Clairsville is filled with an incredible assortment of activities, you should know that plenty of folks choose to have set down roots. No matter what brings you to St. Clairsville, the destination always delivers. St. Clairsville is full of impressive hotels on top of appealing attractions, so you can count on a marvelous stay. Book early to ensure you snag a room!

Your luxury vacation is your chance to live your best life, including eating at 5-star restaurants and getting VIP seats. When you save big by booking on, you can enjoy it all. Thanks to our great prices on hotels, you can always afford to experience the region's most exciting points of interest. After many hours of exploring the city, your luxury hotel is waiting with fine dining and upscale amenities. Take advantage of amenities like an incredible balcony view or indoor pool before the day is over. The luxury accommodations in St. Clairsville will have you feeling the relaxation in no time.

Luxury St. Clairsville Hotels

It's that time; you're prepared to get swept away in St. Clairsville, and is here to save the day. Search through the bounty of ratings and reviews on fantastic hotels and find the perfect vacation rental. 5-Star hotels treat you right, offering things like high end bath amenities and private kitchens. Some of the city's opulent accommodations even feature impeccable penthouses, while others offer tennis courts or salt water pools. Book your dream hotel in St. Clairsville now, and prepare for the vacation of your life!