Find Resorts & Hotels with Spas in St. James, MO

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Top St. James Resorts & Hotels with Spas

No exact matches found, but these alternatives could be just right

Recommended hotels in St. James

Free daily self-serve breakfast
Greenlight Inn & Suites

Greenlight Inn & Suites

2.0 star property
St. James
8.6 out of 10, Excellent, (426)
"Very clean, comfortable bed, warm room very cozy after a long day traveling. Breakfast really good! I recommend this place!"
United States
Maria Victoria
$59 nightly
The price is $66
Jan 1 - Jan 2, 2026
Total with taxes and fees
Greenlight Inn & Suites
Reception
Finns Motel

Finns Motel

2.5 star property
St. James
8.0 out of 10, Very Good, (330)
"Found this awesome (older) hotel. Very comfortable & enjoyed our night stay. Bathroom very small - but again older, very well maintained hotel."
United States
Joyce
$56 nightly
The price is $63
Dec 3 - Dec 4
Total with taxes and fees
Finns Motel
Fridge, microwave, oven, stovetop
Cozy Cottage on Historic Route 66, minutes away from Wineries & Restaurants.

Cozy Cottage on Historic Route 66, minutes away from Wineries & Restaurants.

Saint James
10.0 out of 10, Exceptional, (49)
"Cute place and clean and close to the things we wanting to do "
United States
Tonya L.
$170 nightly
The price is $170
Dec 4 - Dec 5
Total with taxes and fees
Cozy Cottage on Historic Route 66, minutes away from Wineries & Restaurants.
Fridge, microwave, oven, stovetop
Get Cozy in the Country - The Cottage on Luca Hill

Get Cozy in the Country - The Cottage on Luca Hill

2.0 star property
Saint James
10.0 out of 10, Exceptional, (18)
"Nice clean property wirh a good location for us!"
United States
John P.
$195 nightly
The price is $203
Dec 3 - Dec 4
Total with taxes and fees
Get Cozy in the Country - The Cottage on Luca Hill
Fridge, microwave, oven, stovetop
2BR | Pet-Friendly | Fenced Yard | Near Wineries

2BR | Pet-Friendly | Fenced Yard | Near Wineries

Saint James
10.0 out of 10, Exceptional, (21)
"We came for a little family get away and this was the perfect space to do so! "
United States
Trisha E.
$223 nightly
The price is $235
Dec 31 - Jan 1, 2026
Total with taxes and fees
2BR | Pet-Friendly | Fenced Yard | Near Wineries
Fridge, microwave, oven, stovetop
3BR/2BA • BBQ • Patio • Family-Friendly & Clean

3BR/2BA • BBQ • Patio • Family-Friendly & Clean

Saint James
9.8 out of 10, Exceptional, (27)
"Our stay was great, I believe "
United States
Jennifer B.
$228 nightly
The price is $241
Jan 1 - Jan 2, 2026
Total with taxes and fees
3BR/2BA • BBQ • Patio • Family-Friendly & Clean
Fridge, microwave, oven, stovetop
The James Stay on Historic Route 66 • minutes away from Wineries & Restaurants

The James Stay on Historic Route 66 • minutes away from Wineries & Restaurants

Saint James
9.6 out of 10, Exceptional, (24)
"Perfect for a weekend getaway. "
United States
Todd
$174 nightly
The price is $174
Dec 3 - Dec 4
Total with taxes and fees
The James Stay on Historic Route 66 • minutes away from Wineries & Restaurants
Fridge, microwave, oven, stovetop
Townside White House

Townside White House

Saint James
10.0 out of 10, Exceptional, (8)
"This host made my quick stay very easy and comfortable, the house is very nice and well tidy,"
United States
Cheryl K.
$180 nightly
The price is $180
Dec 3 - Dec 4
Total with taxes and fees
Townside White House
Fridge, microwave, oven, stovetop
Vineyard Ridge Farmhouse • 3BR • 2BA • Vineyard View • Fire pit •

Vineyard Ridge Farmhouse • 3BR • 2BA • Vineyard View • Fire pit •

Saint James
10.0 out of 10, Exceptional, (33)
"This was our second stay at this location! Our family feels right at home here… clean, good location and all the amenities! "
United States
Christie C.
$227 nightly
The price is $227
Dec 3 - Dec 4
Total with taxes and fees
Vineyard Ridge Farmhouse • 3BR • 2BA • Vineyard View • Fire pit •
Fridge, microwave, oven, stovetop
The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James

The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James

Saint James
10.0 out of 10, Exceptional, (22)
"Beautiful stay! I love it here! "
United States
kayley h.
$202 nightly
The price is $206
Dec 3 - Dec 4
Total with taxes and fees
The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Find out more about St. James

Top St. James attractions for a relaxing vacation

In the charming town of St. James, Missouri, travelers seeking hotels with spas will find a delightful mix of relaxation and adventure. Begin your journey at the St. James Winery, where you can indulge in tastings of award-winning wines while enjoying the picturesque vineyard views. Afterward, explore the scenic trails at the nearby Meramec River State Park, perfect for hiking and unwinding amidst nature. For a unique experience, visit the St. James Mineral Springs, known for its therapeutic waters, ideal for rejuvenation. The town also boasts local shops and restaurants that showcase Missouri's rich culinary heritage, making it an excellent spot for food lovers. Staying in the heart of St. James, you'll have convenient access to these attractions and can unwind in a spa hotel that offers personalized services and luxurious amenities, ensuring an unforgettable experience for you and your family.

Top St. James Hotel Reviews

Comfort Suites Rolla

Comfort Suites Rolla

10/10 Excellent
"The room was great and the staff was very nice."
Shirley 1-night trip
Posted 13 days ago
Comfort Suites Rolla
Baymont by Wyndham Rolla

Baymont by Wyndham Rolla

10/10 Excellent
"Great people "
Robert 2-night trip
Posted 2 weeks ago
Baymont by Wyndham Rolla

Frequently asked questions

Looking for a spa hotel in St. James?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Be sure to enjoy the wineries during your stay. Hotels with spas are the perfect way to take a break from your routine and add a layer of luxury to your weekend away.
What's there to see and do in St. James?
Enjoy St. James and visit St. James Winery, Rosati Winery Museum, and Maramec Spring Park. If you have a little extra time during your trip, you might want to make a stop at Meramec River and Meramec Vineyards.
What is a St. James spa hotel?
Spa hotels in St. James provide lodging and have a full on-site spa which offers services including massages and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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