Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured St. Lawrence Seaway Business Hotels

See all 111 Hotels in St. Lawrence Seaway
Comfort Inn & Suites Watertown - 1000 Islands

Comfort Inn & Suites Watertown - 1000 Islands

110 Commerce Park Drive, Watertown
2.5 out of 5.0
4.2 out of 5 (1,152 reviews)
Great locationThis wAs the perfect location for a quick trip upstate. Very close to route 81. Nice rooms that are very clean and comfortable. BAthrom was spotless. I would recommend this hotel
  Jan 15, 2018

$98

$98
Best Western University Inn

Best Western University Inn

90 E Main Street, Canton
3.0 out of 5.0
4.1 out of 5 (164 reviews)
Nice and Convenient.Very kind and helpful staff. Clean and comfortable room. One negative: was there on business, so needed to make use of business center. Computers kept crashing, very limited print capabilities, and no copy machine. Restaurant/lounge was busy. Food came out slow, but when it did, it was excellent. ...
  Jan 20, 2018

$149

$149
Best Western Watertown Fort Drum

Best Western Watertown Fort Drum

300 Washington St, Watertown
3.0 out of 5.0
3.8 out of 5 (899 reviews)
Some great perks!We have stayed here many times and are always happy with the staff and amenities. The coffee and cookies are a nice touch and the breakfast sausages are awesome. They had begun renovations and the updates were much needed. We were put in an older room and the difference was notable. Hopefully they'll ...
  Jan 5, 2018

$67

$67
Hampton Inn Potsdam

Hampton Inn Potsdam

169 Market Street, Potsdam
3.0 out of 5.0
4.6 out of 5 (145 reviews)
Excellent facilities easy checkin and checkout. Very pleaseant and friendly staff. Great breakfast and nice host. Very helpful.
  Nov 11, 2017

$134

$134
Hilton Garden Inn Watertown/Thousand Islands

Hilton Garden Inn Watertown/Thousand Islands

1290 Arsenal Street, Watertown
3.5 out of 5.0
4.5 out of 5 (413 reviews)
Nice hotel room was to hotNo complaints nice pool and hot tub room was too hot turn the heat down
  Dec 1, 2017

$110

$110
The Eis House

The Eis House

144 Academy Street, Mexico
3.5 out of 5.0
4.3 out of 5 (40 reviews)
Eis House - Mexico, NYThe room was clean and comfortable. The bathroom looked to have been fairly recently remodeled. Registration is a little unique. You need to register for your room at the bar after 3PM. The bar and restaurant is only open from 2PM through the evening. The internet service is poor due to a very weak ...
  Sep 7, 2017

$55

$55
Days Inn Evans Mills/Fort Drum

Days Inn Evans Mills/Fort Drum

25940 US Route 11, Evans Mills
2.5 out of 5.0
4.3 out of 5 (470 reviews)
Great hotel, very friendly staff. I come up every few months to visit friends and family, this is the only hotel I will ever stay at!
  Jan 17, 2018

$52

$52
Quality Inn Massena

Quality Inn Massena

10 W Orvis St, Massena
2.5 out of 5.0
3.5 out of 5 (139 reviews)
Centrally located to places of my interest I have stayed here before only because the experience each time is pleasant
  Oct 2, 2017

$100

$100
University Suites Hotel

University Suites Hotel

6000 US 11, Canton
3.0 out of 5.0
3.7 out of 5 (215 reviews)
Canton, NYVery nice hotel with clean and spacious rooms. Grandsons enjoyed the pool. Breakfast area was neat and clean with many offerings.
  Dec 11, 2017

$93

$93
Holiday Inn Express Hotel & Suites Watertown-Thousand Island

Holiday Inn Express Hotel & Suites Watertown-Thousand Island

1290 Arsenal St, Watertown
3.0 out of 5.0
4.5 out of 5 (488 reviews)
Great place to stayWonderful friendly and helpful staff, clean, modern rooms. Included in the price is an awesome hot breakfast. Pool is open until 10pm. I would happily stay here again.
  Dec 28, 2017

$89

$89
Motel 6 Calcium, NY

Motel 6 Calcium, NY

8000 Virginia Smith Drive, Calcium
2.0 out of 5.0
3.8 out of 5 (750 reviews)
The staff is very friendly, and has been the few times we've stayed there. They were under construction, doing some remodeling that should look very nice.
  Jan 20, 2018

$40

$40
Ramada Watertown

Ramada Watertown

21000 NY State Rt 3, Watertown
3.0 out of 5.0
3.5 out of 5 (581 reviews)
To many flies, I think I killed about 7 of them. The people were very friendly.
  Dec 9, 2017

$72

$72
Quality Inn & Suites Riverfront

Quality Inn & Suites Riverfront

70 E 1st St, Oswego
2.5 out of 5.0
4.3 out of 5 (75 reviews)
I arrived and they did NOT have my reservation. It was pleasant, Breakfastwas good, staff were very accomodating
  Dec 24, 2017

$103

$103
Red Roof Inn PLUS+ & Suites Malone

Red Roof Inn PLUS+ & Suites Malone

42 Finney Blvd, Malone
3.0 out of 5.0
4.3 out of 5 (241 reviews)
WELL PRICED, CLEAN , CONVENIENTMY SECOND STAY AT THIS LOCATION AND I WAS GLAD TO COME BACK. NOT ALL LOCATIONS OF THIS CHANGE ARE AS MODERN AND CLEAN.
  Nov 17, 2017

$90

$90
Super 8 Pulaski

Super 8 Pulaski

3800 State Route 13, Pulaski
2.0 out of 5.0
4.0 out of 5 (164 reviews)
Super8 in PulaskiWe stay in this hotel year after year for XC trips. It is quiet, clean and has all we need.
  Dec 31, 2017

$81

$81
Travelodge Watertown

Travelodge Watertown

1190 Arsenal Street, Watertown
3.0 out of 5.0
3.9 out of 5 (483 reviews)
Had a leaky fridge but very good experience, other then tha
  Nov 25, 2017

$76

$76
Hampton Inn Watertown

Hampton Inn Watertown

155 Commerce Park Dr, Watertown
3.0 out of 5.0
4.5 out of 5 (426 reviews)
Nice breakfast. Good hotel when shopping. Clean and not too busy.
  Jan 4, 2018

$84

$84
The Clarkson Inn

The Clarkson Inn

1 Main St, Potsdam
4.0 out of 5.0
4.6 out of 5 (232 reviews)
Lovely Victorian hotelThis lovely small hotel has wonderful amenities and ambiance. Weekends include afternoon tea in the reception area complete with fireplace and comfortable seating. The rooms are large and many include a nice seating area. Each room includes comfortable beds, beautiful furnishings, Kuerig coffee maker, ...
  Dec 20, 2017

$145

$145
Super 8 Massena NY

Super 8 Massena NY

84 Grove St, Massena
2.5 out of 5.0
3.7 out of 5 (362 reviews)
Reasonable Hotels at fair prices.The check in was very pleasent. Rooms very nice. Let me say this high dollar hotels do not provide microwaves or refrigerators thank you.
  Jan 7, 2018

$54

$54
1000 Islands Harbor Hotel

1000 Islands Harbor Hotel

200 Riverside Drive, Clayton
4.0 out of 5.0
4.8 out of 5 (86 reviews)
As usual the staff is awesome. Overall just a great Hotel
  Jan 16, 2018

$95

$95
Map

Recently booked Business Hotels in St. Lawrence Seaway

The Clarkson Inn
4.0 out of 5.0
Last booking: 46 minutes ago
1000 Islands Harbor Hotel
4.0 out of 5.0
Last booking: 55 minutes ago
Red Roof Inn PLUS+ & Suites Malone
3.0 out of 5.0
Last booking: 1 hour ago
Holiday Inn Express Hotel & Suites Watertown-Thousand Island
3.0 out of 5.0
Last booking: 1 hour ago
Comfort Inn & Suites Watertown - 1000 Islands
2.5 out of 5.0
Last booking: 1 hour ago
Ramada Watertown
3.0 out of 5.0
Last booking: 2 hours ago
Quality Inn & Suites Riverfront
2.5 out of 5.0
Last booking: 3 hours ago
Potsdam Inn
3.0 out of 5.0
Last booking: 5 hours ago
Riveredge Resort
3.5 out of 5.0
Last booking: 6 hours ago

Pocket Guide: Business Hotels in St. Lawrence Seaway

Search for hotels in St. Lawrence Seaway on Expedia. You can easily find your hotels in St. Lawrence Seaway using one of the methods below:

  • View our selection of featured hotels in St. Lawrence Seaway
  • Use the map to find hotels in the St. Lawrence Seaway neighborhood you prefer
  • Use the filters to see hotels in a specific area of St. Lawrence Seaway, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in St. Lawrence Seaway
  • Enter your travel dates to view the best deals on hotels in St. Lawrence Seaway - while they last