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Top St. Louis Neighborhoods for Business Hotels

Clayton
5 hotels

Clayton Plaza Hotel

3.5 out of 5.0
from

$100

Featured St. Louis Business Hotels

See all 322 Hotels in St. Louis
Clayton Plaza Hotel

Clayton Plaza Hotel

7750 Carondelet Avenue, St. Louis
3.5 out of 5.0
4.1 out of 5 (3,006 reviews)
Mini fancy hotel It’s like a mini fancy hotel. Small but super glitzy cute entrance Staff was nice andnrooms were very clean. Beds are pretty comfy. 8 min drive from Wash U so it was perfect. Great especially for the price
  Jan 15, 2018

$100

$100
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St, St. Louis
4.5 out of 5.0
4.3 out of 5 (5,026 reviews)
Clean, nice large rooms, great location. I would recommend this hotel to anyone I know visiting St. Louis. It is not overall expensive and the restaurant in the hotel is convenient for us not used to the cold weather during winter.
  Jan 12, 2018

$99

$99
City Place St. Louis - Downtown Hotel

City Place St. Louis - Downtown Hotel

200 North 4th Street, St. Louis
4.0 out of 5.0
3.3 out of 5 (3,732 reviews)
4th of JulyTraveled with my 2 kids- 11&12yo. Stayed 2 nights. July 3rd & 4th. Check in was quick & painless. They were quite busy, but didn't seem to rush me. Front desk was friendly. Requested a room facing the arch. Got a room on the 6th floor with a balcony. Valet parking was $20 or $10 to self park. Short ...
 Tim Jul 7, 2013

$83

$83
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

777 Casino Center Drive, Maryland Heights
4.0 out of 5.0
3.8 out of 5 (1,899 reviews)
STayed for the fun plus son taking plane back to ca. Great service having the shuttle take him to airport . TOTALLY ENJOYED OUR STAY.
  Jan 16, 2018

$82

$82
Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur

828 N New Ballas Rd, St. Louis
3.0 out of 5.0
4.4 out of 5 (1,032 reviews)
Great neighborhoodThe beds are so comfortable! Very clean and nice hotel
  Dec 17, 2017

$76

$76
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St, St. Louis
4.5 out of 5.0
4.4 out of 5 (772 reviews)
Wonderful Boutique-like Hotel Classy and Warm describes the staff and hotel. Rooms are clean, very well thought out and bed was very comfortable. Fitness suite had a large layout with a larger than average assortment of equipment that was well maintained. Breakfast at the Bar/Restaurant named Robies was fantastic! No doubt I ...
  Jan 17, 2018

$129

$129
The Wildwood Hotel

The Wildwood Hotel

2801 Fountain Pl, Wildwood
4.0 out of 5.0
4.5 out of 5 (2,416 reviews)
Neat PlaceWe were passing through and found this place to be a neat place to stay. We had a whirlpool room and it was really nice.
  Jan 9, 2018

$95

$95
La Quinta Inn & Suites St. Louis Westport

La Quinta Inn & Suites St. Louis Westport

11805 Lackland Rd, Maryland Heights
3.0 out of 5.0
4.1 out of 5 (901 reviews)
The front desk staff was very kind and helpful.Not only was my check in smooth, but the front desk staff were friendly!
  Jan 16, 2018

$75

$75
Comfort Inn St Louis - Westport

Comfort Inn St Louis - Westport

12031 Lackland Rd, Maryland Heights
3.0 out of 5.0
3.9 out of 5 (740 reviews)
Nice hotel convenient to businessI stayed only 1 night, but was pleased with the cleanliness, comfort, & overall fit & finish of the room.
 David Jul 12, 2013

$81

$81
Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield

333 Chesterfield Center East, Chesterfield
3.5 out of 5.0
4.7 out of 5 (789 reviews)
Stop on long road tripExcellent for family of 5. Great breakfast and service
  Jan 18, 2018

$99

$99
La Quinta Inn & Suites St. Louis Airport - Riverport

La Quinta Inn & Suites St. Louis Airport - Riverport

13615 Riverport Drive, Maryland Heights
3.5 out of 5.0
4.1 out of 5 (840 reviews)
bad room overlooking the lobby. noisy all nightnoisy as hell - not from traffic, but from people in the lobby/breakfast area. all night. nice hotel - stay away from such rooms
  Jan 18, 2018

$72

$72
Hilton St. Louis Downtown at the Arch

Hilton St. Louis Downtown at the Arch

400 Olive St, St. Louis
4.5 out of 5.0
4.3 out of 5 (1,255 reviews)
Amazing!!!Quick, friendly check in, beautiful lobby, easy access to the room, AND the room was PERFECT! We will definitely be back!
  Jan 14, 2018

$89

$89
St. Louis City Center Hotel

St. Louis City Center Hotel

400 S 14th St, St. Louis
4.0 out of 5.0
3.8 out of 5 (3,335 reviews)
For an event in St. Louis this hotel is a perfect location with close proximity to food and entertainment. Our room had a fold out couch that had springs missing and our phone didn’t have buttons. The staff was quick with requests and check in and out was seamless.
  Jan 16, 2018

$95

$95
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street, St. Louis
3.5 out of 5.0
4.6 out of 5 (3,093 reviews)
Two days in JulyExperience was OK. Nice location, walking distance to the arch.Old style, might need some renovation (aka some kind of Chinese hotel of the 90s).Room proposed had a very small window, it felt like in a cave. The second room was better, with view on the arch, but in a secondary building to the main ...
 XD Jul 14, 2013

$130

$130
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

1820 Market Street, St. Louis
4.0 out of 5.0
4.3 out of 5 (1,798 reviews)
Unique Train station hotel Beautiful train station hotel with breathtaking lobby and model trains- very fun for families and kids!
  Dec 22, 2017

$114

$114
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

9801 Natural Bridge Road, Berkeley
4.0 out of 5.0
4.2 out of 5 (1,244 reviews)
Nice hotel close to the airport Clean spacious rooms with comfortable bed. Very updated. Lots of outlets all over the room. Great shuttle service close to the airport.
  Jan 12, 2018

$89

$89
Wingate by Wyndham St. Charles MO

Wingate by Wyndham St. Charles MO

32 Research Park Circle, St. Charles
3.5 out of 5.0
4.3 out of 5 (905 reviews)
Great place! Hotel is easily accessible, room was clean and comfortable. Breakfast was pretty good.. I will suggest to have a more neutral show on the TV in the common area. Subjecting everyone to FOX news made for an incredibly unpleasant dining experience. That aside it was a great place to stay!
  Jan 6, 2018

$88

$88
Courtyard by Marriott St Louis Westport Plaza

Courtyard by Marriott St Louis Westport Plaza

11888 Westline Industrial Dr, Maryland Heights
3.0 out of 5.0
4.4 out of 5 (990 reviews)
The staff made the place.....The staff were genuinely very helpful and nice, although there is always one that lets the team down, which is such a shame, as every other member of the staff were superb. My room was what I expected for the price and location. The food was reasonable, especially for the USA. The hotel was clean ...
  Jan 9, 2018

$84

$84
HoteLumiere at the Arch

HoteLumiere at the Arch

999 N. 2nd St., St. Louis
4.5 out of 5.0
3.2 out of 5 (432 reviews)
CleanClean, comfortable, accommodating. Needed a roll away bed, was there in 10 minutes.
  Dec 31, 2017

$92

$92
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

2211 Market Street, St. Louis
3.5 out of 5.0
4.3 out of 5 (1,603 reviews)
good hotel for locationreasonably priced for being downtown and has all the amenities you could need.
  Jan 16, 2018

$90

$90
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