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Featured St. Louis Casino Hotel

See all 261 Hotels in St. Louis
River City Casino & Hotel
River City Casino & Hotel
777 River City Casino Blvd, St. Louis
4.0 out of 5.0
4.5 out of 5 (238 reviews)
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Wonderful hotel Friendly staff, great amenities, very comfortable and accommodating. Will definitely revisit.
  May 20, 2017

$149

$149
Americas Best Value Inn St. Louis/Downtown
Americas Best Value Inn St. Louis/Downtown
1100 N 3rd St, St. Louis
2.0 out of 5.0
2.5 out of 5 (114 reviews)
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Had a wonderful view Front desk was wonderful, he moved us to a better room, we enjoyed our stay for the price!
  Jan 27, 2017

$90

$90
Four Seasons Hotel St Louis
Four Seasons Hotel St Louis
999 North Second Street, St. Louis
5.0 out of 5.0
4.8 out of 5 (92 reviews)
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Good hotel, location has some good/bad points The experience staying at the Four Seasons in St. Louis was great overall. The staff were uniformly helpful and the room excellent. The attached casino is fine if you might want that facility - when I was there the restaurants attached to the casino were only open part-time with one exception, and ...
  May 5, 2017

$269

$269
Casino Queen Hotel
Casino Queen Hotel
200 South Front Street, East St. Louis
3.0 out of 5.0
3.9 out of 5 (324 reviews)
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Staff friendly Staff was excellent, called us when room was ready for early checkin. Room view was Awesome and a good size. The only negative, air unit loud when it came on to cool room.
  May 23, 2017

$109

$109
Comfort Suites
Comfort Suites
1400 S 5th St, St. Charles
2.5 out of 5.0
4.1 out of 5 (87 reviews)
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The internet wi-go access sucked takes forever to get a connection to work. Then you have to reconnect constantly.The ice Machine on 3rd and first floor didn't work. Told clerk and she said go to the bar for ice. At 7 in the morning ? Haha. It is closed ..... geez room was fine though.
  May 23, 2017

$99

$99
HoteLumiere at the Arch
HoteLumiere at the Arch
999 N. 2nd St., St. Louis
4.0 out of 5.0
2.7 out of 5 (43 reviews)
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Nice hotel close to the Arch Park. Overall stay was fine since it was only for one night, but our rooms air conditioner was not working properly so it made for a stuffy nights sleep.
  May 15, 2017

$125

$125
Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
1 Ameristar Blvd, St. Charles
4.5 out of 5.0
4.5 out of 5 (290 reviews)
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Nice hotel. Rooms were gorgeous! Enjoyed my stay. Hotel easy to find. Nice shops inside
  May 16, 2017

$159

$159
Country Inn & Suites By Carlson, St. Charles, MO
Country Inn & Suites By Carlson, St. Charles, MO
1190 S Main St, St. Charles
2.5 out of 5.0
4.5 out of 5 (255 reviews)
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Very pleasant stay. Nice looking building close to old st charles and restaurants.
  May 16, 2017

$111

$111
Drury Inn & Suites Convention Center - St. Louis, MO
Drury Inn & Suites Convention Center - St. Louis, MO
711 N Broadway, St. Louis
3.0 out of 5.0
4.5 out of 5 (199 reviews)
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Staff was excellent and extraordinarily helpful. Great food recommendations and knowledgeable about what to see in the area.
  May 24, 2017

$140

$140
Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive, Maryland Heights
3.5 out of 5.0
3.7 out of 5 (431 reviews)
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Date night fun! My partner and I like to do random things for a date night, and lately we've been on a kick of staying a night at a casino hotel. We enjoyed the buffet, and even if you're not a buffet person, there's plenty of other dining options available. The casino itself is quite large, and there's plenty of ...
  May 25, 2017

$111

$111
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St. Louis Casino Hotel Information

Hit it big during your stay in St. Louis, Missouri.

  • Score a hotel located near the tables and slot machines
  • Use the mobile booking options for additional discounts
  • Win the jackpot when you score the cheapest deals around right here

Take Lady Luck out for a night on the town during your vacation in St. Louis.

First spend some time getting to know the city before testing your lucky streak. Spend some time strolling in the Missouri Botanical Garden, marveling at the Gateway Arch, and exploring the quirky exhibits at the City Museum. When it’s time to give your lucky rabbit a run for your money, check out the casinos in St. Louis, MO. Pull your best poker face at the game tables at Hollywood Casino, or responsibly play the slot machines at the River City Casino. Play a round or two on the game floor, and then retreat to one of the hotels near the casinos in St. Louis for easy access to the entertainment.

You’ll feel like you have a royal flush in your hands when you book with Expedia.com. We offer cheap deals on hotels near the casinos in St. Louis, Missouri, which let you spend more on your activities and less on your reservations. Check out our selection of hotels to find just what you had in mind, whether that’s a place with a fitness center and lounge or an accommodation with pool and conference space. After picking the perfect hotel for your lucky vacation, take advantage of our discounts on car rentals in St. Louis. Forget about rolling the dice when it comes to making reservations, and instead book all your reservations right here with Expedia.com.