Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured St. Louis Hyatt Hotels Hotels

See all 265 Hotels in St. Louis
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St, St. Louis
4.0 out of 5.0
4.3 out of 5 (1,640 reviews)
Comfortable Very much enjoyed my stay at this hotel. The staff was welcoming and helpful. The room was extremel … - 

$119

$119
Map

Recently booked St. Louis hotels

Courtyard by Marriott St. Louis St. Peters
3.0 out of 5.0
Last booking: 3 minutes ago
Drury Inn & Suites St. Louis Creve Coeur
3.0 out of 5.0
Last booking: 6 minutes ago
Pear Tree Inn St. Louis Fenton
2.0 out of 5.0
Last booking: 12 minutes ago
La Quinta Inn & Suites St. Louis Westport
2.5 out of 5.0
Last booking: 15 minutes ago
Extended Stay America - St. Louis - Earth City
2.5 out of 5.0
Last booking: 17 minutes ago
Days Inn Collinsville
2.5 out of 5.0
Last booking: 24 minutes ago
Home2 Suites by Hilton St. Louis/Forest Park
2.5 out of 5.0
Last booking: 26 minutes ago
The Hotel Majestic St. Louis
4.0 out of 5.0
Last booking: 32 minutes ago
The Lodge Hotel & Banquets St. Louis
2.0 out of 5.0
Last booking: 40 minutes ago

Hyatt Hotels St. Louis Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Hyatt Hotels hotels in St. Louis, Missouri. Known for well-appointed rooms and friendly, personalized service, each of the top Hyatt Hotels St. Louis hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some St. Louis Hyatt Hotels locations may even offer extra little benefits and discounts for frequent travelers.