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Featured St. Louis Independent Hotels

See all 268 Hotels in St. Louis
Seven Gables Inn

Seven Gables Inn

26 North Meramec Avenue, St. Louis
3.5 out of 5.0
4.1 out of 5 (106 reviews)
Wedding Party Place of Choice We were in St. Louis for our Grandson's wedding. The entire family attending from 'other places' ch … - 

$135

$135
Clayton Plaza Hotel

Clayton Plaza Hotel

7750 Carondelet Avenue, St. Louis
3.5 out of 5.0
3.9 out of 5 (553 reviews)
Family friendly and business friendly Loved the wood floors. Lobby Beautiful. Game room and pool area could have been only slightly tidie … - 

$109

$109
St. Louis City Center Hotel

St. Louis City Center Hotel

400 S 14th St, St. Louis
3.5 out of 5.0
3.6 out of 5 (815 reviews)
Close to Scottrade, Downtown, Busch Stadium Hotel is across from Scottrade Center and within walking distance of downtown government buildings … - 

$103

$103
The Cheshire

The Cheshire

6300 Clayton Rd, Richmond Heights
4.0 out of 5.0
4.1 out of 5 (378 reviews)
Good location The carpets in the hallways were dirty on the 2nd and 3rd floor. The hotel staff that came to notif … - 

$151

$151
Hotel Ignacio Saint Louis

Hotel Ignacio Saint Louis

3411 Olive St, St. Louis
3.5 out of 5.0
4.4 out of 5 (76 reviews)
Nice little spot to book on a business venture. only 10min from downtown and the restaurants attach … - 

$170

$170
Fleur-de-Lys Mansion

Fleur-de-Lys Mansion

3500 Russell Blvd, St. Louis
4.0 out of 5.0

$187

$187
Crowne Plaza Riverfront at the Arch

Crowne Plaza Riverfront at the Arch

200 N 4th Street, St. Louis
3.5 out of 5.0
3.2 out of 5 (1,143 reviews)
AKA Crowne Plaza Riverfront at the Arch, St. Louis Expedia didn't notify us of the name change and only found out when the cab from the airport droppe … - 

$71

$71
Moonrise Hotel

Moonrise Hotel

6177 Delmar Blvd, St. Louis
4.0 out of 5.0
4.7 out of 5 (528 reviews)
Very close to wedding venue attended The area was great for walking as Forest Park was close along its museums and trails. The Loop had … - 

$179

$179
The Hotel Majestic St. Louis

The Hotel Majestic St. Louis

1019 Pine St, St. Louis
4.0 out of 5.0
3.9 out of 5 (455 reviews)
Nice hotel in downtown St Louis A good experience. Clean room, very good breakfast, very friendly staff. - 

$149

$149
Missouri Athletic Club

Missouri Athletic Club

405 Washington Ave, St. Louis
3.5 out of 5.0
3.9 out of 5 (220 reviews)
Old-fashioned club with downtown convenience Still functioning as an athletic club, this place has four floors available for overnight guests. I … - 

$112

$112
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Independent St. Louis Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in St. Louis, Missouri. Known for well-appointed rooms and friendly, personalized service, each of the top Independent St. Louis hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some St. Louis Independent locations may even offer extra little benefits and discounts for frequent travelers.