Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured St. Louis La Quinta Inn & Suites Hotels

See all 265 Hotels in St. Louis
La Quinta Inn & Suites O'Fallon, IL - St. Louis

La Quinta Inn & Suites O'Fallon, IL - St. Louis

136 Regency Park, O'Fallon
2.5 out of 5.0
4.1 out of 5 (57 reviews)
It was convenient. The entire staff was very pleasant. I think our breakfast host Delores helped br … - 

$89

$89
La Quinta Inn & Suites St. Louis Westport

La Quinta Inn & Suites St. Louis Westport

11805 Lackland Rd, Maryland Heights
2.5 out of 5.0
4.1 out of 5 (264 reviews)
Great accommodations, great stay Breakfast: good variety. Comfortable room and beds. Would come again. - 

$85

$85
La Quinta Inn St. Louis Hazelwood - Airport North

La Quinta Inn St. Louis Hazelwood - Airport North

318 Taylor Rd, Hazelwood
2.5 out of 5.0
3.1 out of 5 (167 reviews)
Good, breakfast could be more wholesome. Thank you. - 

$74

$74
La Quinta Inn & Suites St. Louis Airport - Riverport

La Quinta Inn & Suites St. Louis Airport - Riverport

13615 Riverport Drive, Maryland Heights
3.0 out of 5.0
4.0 out of 5 (191 reviews)
Great oasis Very pleasant experience,Good people,Good location,Exceptional service,Home away from home,Would re … - 

$84

$84
La Quinta Inn & Suites Collinsville

La Quinta Inn & Suites Collinsville

6 Gateway Dr, Collinsville
2.5 out of 5.0
3.9 out of 5 (171 reviews)
Sweat the details more Overall well-maintained budget hotel with a very pleasant and helpful staff. Good value for the mon … - 

$67

$67
La Quinta Inn & Suites Pontoon Beach

La Quinta Inn & Suites Pontoon Beach

14 Regency Park Dr, Pontoon Beach
2.5 out of 5.0
3.9 out of 5 (36 reviews)
Good hotel My experience was good. When we arrived to the hotel we where greeted by a friendly staff member. T … - 

$79

$79
Map

Recently booked St. Louis hotels

Motel 6 Maryland Heights, MO
2.0 out of 5.0
Last booking: 3 minutes ago
Red Roof Plus St. Louis - Forest Park / Hampton Ave.
2.5 out of 5.0
Last booking: 5 minutes ago
HoteLumiere at the Arch
4.0 out of 5.0
Last booking: 8 minutes ago
Quality Inn O'fallon
2.5 out of 5.0
Last booking: 12 minutes ago
Drury Plaza Hotel St. Louis Chesterfield
3.0 out of 5.0
Last booking: 12 minutes ago
Hollywood Casino & Hotel St. Louis
3.5 out of 5.0
Last booking: 14 minutes ago
The Lodge Hotel & Banquets St. Louis
2.0 out of 5.0
Last booking: 19 minutes ago
Residence Inn By Marriott St Louis Chesterfield
3.0 out of 5.0
Last booking: 21 minutes ago
Best Western St. Louis Inn
2.5 out of 5.0
Last booking: 23 minutes ago