Find Resorts & Hotels with Spas in St. Louis, MI

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Top St. Louis Resorts & Hotels with Spas

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Recommended hotels in St. Louis

Room, 2 Queen Beds, Accessible, Non Smoking (Mobility, Roll-In Shower) | Desk, blackout drapes, iron/ironing board, free cribs/infant beds
Days Inn & Suites by Wyndham Mt Pleasant

Days Inn & Suites by Wyndham Mt Pleasant

2.5 star property
Mount Pleasant
7.8 out of 10, Good, (1003)
"Clean rooms.and very friendly staff"
United States
Amanda
$76 nightly
The price is $84
Jan 2 - Jan 3, 2026
Total with taxes and fees
Days Inn & Suites by Wyndham Mt Pleasant
Property amenity
Alma Motel Alma

Alma Motel Alma

2.0 star property
Alma
7.8 out of 10, Good, (497)
"Very clean, comfortable beds."
United States
Rosanne
$61 nightly
The price is $65
Dec 11 - Dec 12
Total with taxes and fees
Alma Motel Alma
Bar (on property)
Comfort Inn & Suites and Conference Center

Comfort Inn & Suites and Conference Center

2.5 star property
Mount Pleasant
9.2 out of 10, Wonderful, (1002)
"Great location and convenient to CMU. All around comfortable facilities and the bed was super comfy!"
United States
Jim
$107 nightly
The price is $119
Dec 14 - Dec 15
Total with taxes and fees
Comfort Inn & Suites and Conference Center
Exterior
Hampton Inn Mt. Pleasant

Hampton Inn Mt. Pleasant

2.5 star property
Mount Pleasant
9.0 out of 10, Wonderful, (1002)
"The room was extremely comfortable and the staff was amazing. Will definitely stay again "
United States
Paula
$99 nightly
The price is $110
Dec 15 - Dec 16
Total with taxes and fees
Hampton Inn Mt. Pleasant
Exterior
Holiday Inn Midland by IHG

Holiday Inn Midland by IHG

3.0 star property
Midland
9.2 out of 10, Wonderful, (1003)
"Great hotel with great hospitality!"
United States
derek
$96 nightly
The price is $107
Dec 21 - Dec 22
Total with taxes and fees
Holiday Inn Midland by IHG
Reception
Fairfield Inn & Suites by Marriott Midland

Fairfield Inn & Suites by Marriott Midland

2.5 star property
Midland
9.4 out of 10, Exceptional, (241)
"It was a comfortable place to stay and quiet area around."
United States
yen
$123 nightly
The price is $137
Dec 21 - Dec 22
Total with taxes and fees
Fairfield Inn & Suites by Marriott Midland
Staircase
Saravilla Bed and Breakfast

Saravilla Bed and Breakfast

3.0 star property
Alma
9.8 out of 10, Exceptional, (224)
"A beautiful historic home - enjoyed our stay!"
United States
Gabrielle
$140 nightly
The price is $148
Dec 10 - Dec 11
Total with taxes and fees
Saravilla Bed and Breakfast
Front of property
Quality Inn Mount Pleasant

Quality Inn Mount Pleasant

2.5 star property
Mount Pleasant
8.0 out of 10, Very Good, (1000)
"Great location "
United States
Shaun
$85 nightly
The price is $94
Dec 10 - Dec 11
Total with taxes and fees
Quality Inn Mount Pleasant
Exterior
Ginkgo Tree Inn

Ginkgo Tree Inn

3.5 star property
Mount Pleasant
9.8 out of 10, Exceptional, (88)
"The new owners are very accomodating. Breakfast was delicious and the property has a very nice peaceful vibe."
United States
Charles
$194 nightly
The price is $205
Dec 10 - Dec 11
Total with taxes and fees
Ginkgo Tree Inn
Standard Double Room, 2 Double Beds, Non Smoking | 1 bedroom, premium bedding, desk, blackout drapes
Sleep Inn Midland

Sleep Inn Midland

2.5 star property
Midland
8.4 out of 10, Very Good, (889)
"Room was wonderful and clean! Loved the pool and the breakfast was adequate! It is a great value for the price!!!"
United States
Lisa
$68 nightly
The price is $75
Jan 4 - Jan 5, 2026
Total with taxes and fees
Sleep Inn Midland
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Louis Hotel Reviews

Baymont by Wyndham Mt. Pleasant

Baymont by Wyndham Mt. Pleasant

10/10 Excellent
"Extremely friendly staff, good beds and breakfast, clean pool and hot tub. We enjoyed our overnight stay. "
Shawna 1-night trip
Posted 2 days ago
Baymont by Wyndham Mt. Pleasant

Frequently asked questions

Looking to vacation at a spa hotel in St. Louis?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the opera and restaurants in St. Louis—your day trip starts here. Be sure to enjoy activities like horseback riding and golfing during your stay. Spa hotels are a great way to break out of your daily routine and add a layer of luxury to your weekend away.
What's there to see and do in St. Louis?
Take in some sights and attractions while you're in St. Louis by visiting Leppien City Park, McGuirk Arena, and Bucks Run Golf Club. If you have a little extra time during your trip, you might want to check out Soaring Eagle Casino and Resort and Soaring Eagle Waterpark.
What is a St. Louis spa hotel?
Spa hotels in St. Louis feature full on-site spas offering services including couples massages and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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