Beginning of main content

Search over 1,000,000 properties worldwide and 550 airlines worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Check prices on hotels in Syracuse

Best deal Jun 28 - Jun 30
Tonight May 25 - May 26
This weekend May 31 - Jun 2
Next weekend Jun 7 - Jun 9

Featured Syracuse Luxury Hotels

See all 169 Properties in Syracuse

Estimated price for 1 night/2 adults

Mirbeau Inn and Spa
Mirbeau Inn and Spa
4.0 out of 5.0 851 West Genesee Street, Skaneateles, NY
Free Cancellation
4.9/5 (64 reviews)
$255/ night for 2 guests

The most relaxing and luxurious place to spend time

Reviewed on May 22, 2019
Marriott Syracuse Downtown
Marriott Syracuse Downtown
4.0 out of 5.0 100 East Onondaga Street, Syracuse, NY
Free Cancellation
4.4/5 (490 reviews)
$134/ night for 2 guests

A Beautiful, gracious presence. A throwback to a glamorous era. It is a very special place. A true gem for Syracuse.

Reviewed on May 12, 2019
Maplewood Suites Extended Stay- Syracuse/Airport
Maplewood Suites Extended Stay- Syracuse/Airport
3.5 out of 5.0 400 7th North St., Liverpool, NY
Free Cancellation
4.4/5 (1,549 reviews)
$89/ night for 2 guests

Excellent place to stay in Syracuse. Very convenient location and great amenities.

Reviewed on May 24, 2019
Budget Inn - Syracuse Airport
Budget Inn - Syracuse Airport
1.5 out of 5.0 901 S Bay Rd, Cicero, NY
Free Cancellation
3.8/5 (241 reviews)
$60/ night for 2 guests

For a quick stay it was good, if it snows be careful as they only plow out the parking SPOTS not the whole parking lot.

Reviewed on Feb 20, 2019
Knights Inn Liverpool
Knights Inn Liverpool
2.0 out of 5.0 430 Electronics Pkwy, Liverpool, NY
Free Cancellation
4.0/5 (1,684 reviews)
$49/ night for 2 guests

Nice price and easy to check in. breakfast was pretty good!

Reviewed on May 17, 2019
Genesee Grande Hotel and Suites
Genesee Grande Hotel and Suites
3.5 out of 5.0 1060 E Genesee St, Syracuse, NY
Free Cancellation
4.2/5 (1,362 reviews)
$101/ night for 2 guests

Clean, well outfitted room (a fridge would have been nice, though) and quality wise certainly everything up to the standards you'd expect from a hotel of this price range. The location is convenient with all basic shopping needs within only a block or two. Reliable wifi is worth mentioning, as that's ...

Reviewed on May 23, 2019
Red Roof Inn Syracuse
Red Roof Inn Syracuse
2.0 out of 5.0 6614 North Thompson Road, Syracuse, NY
Free Cancellation
3.6/5 (1,672 reviews)
$51/ night for 2 guests

There was a fairly loud, major incident that went on for quite awhile during the early hours of the morning. I'm not sure but the police may have been called.

Reviewed on May 4, 2019
Super 8 by Wyndham Liverpool/Syracuse North Airport
Super 8 by Wyndham Liverpool/Syracuse North Airport
2.0 out of 5.0 421 7th North Street, NYS Thruway(I-90) Ex 36 & 37, Liverpool, NY
Free Cancellation
3.9/5 (1,787 reviews)
$56/ night for 2 guests

The room was fine for the price. Location great right off 81 and so close to the Destiny Mall. Room was clean as was bathroom. They state they are going to be upgrading lobby which needs a huge improvement and will really help this tired property. Staff were professional. We missed breakfast as it ...

Reviewed on May 20, 2019
Quality Inn & Suites Fairgrounds
Quality Inn & Suites Fairgrounds
3.0 out of 5.0 100 Farrell Rd, Syracuse, NY
Free Cancellation
3.2/5 (32 reviews)
$68/ night for 2 guests

Great and convenient to the event IHSA competition

Reviewed on May 5, 2019
Map

Recently booked Luxury Hotels in Syracuse

Days Inn by Wyndham Syracuse
2.0 out of 5.0
Last booking: 2 minutes ago
Comfort Inn & Suites Airport
3.0 out of 5.0
Last booking: 5 hours ago
Best Western Plus East Syracuse Inn
3.0 out of 5.0
Last booking: 6 hours ago
Ramada by Wyndham East Syracuse Carrier Circle
3.0 out of 5.0
Last booking: 6 hours ago
Knights Inn Liverpool
2.0 out of 5.0
Last booking: 7 hours ago
Hotel Skyler Syracuse Tapestry Collection by Hilton
3.0 out of 5.0
Last booking: 7 hours ago

When you want some respite from the hustle and bustle and you're ready to enjoy some peace and quiet, you'll be happy to land in Syracuse. As one of the most interesting destinations for adventurers who crave a slow-paced vacation, Syracuse aims to please. Exquisite eats, fascinating sites, and chances to take terrific photos: these are just some of the benefits of visiting Syracuse. Of course, you'll book a room at a luxury hotel! Anything less than the best is for the birds. While you're here, you'll also snag seats to the most exciting shows, treat yourself to decadent dishes, and get in line to see the coolest attractions. Book your upscale hotel in Syracuse on Expedia.com today and start your vacation off on the right (well-dressed) foot.

5-Star Vacations in Syracuse

If you doubt that Syracuse is full of an intoxicating assortment of activities, keep in mind that 144,142 people choose to live here. Whether you’re looking to spend your vacation dining on haute cuisine or browsing art galleries in Syracuse, you'll never be disappointed. Syracuse is full of outstanding hotels on top of appealing attractions, so you can count on a remarkable stay. Book well in advance to get a room with a view!

An upscale vacation begs for you to explore day spas, art, and local museums. When you save big by booking on Expedia.com, you can enjoy it all. Thanks to our spectacular room rates, you can always afford to stop by the area's most intriguing activities. After many hours of seeing the sights, your luxury hotel is waiting with a wonderful meal and impressive amenities. Before you drift off to dreamland, order a glass of wine to your room and sip on it at your leisure. The luxury hotels in Syracuse will have you basking in bliss in no time.

Luxury Syracuse Hotels

There's no better time than the present to book an escape in The Salt City, and Expedia.com is here to make the process painless. Search through the abundance of reviews on dozens of hotels until you spot the perfect place to stay. Luxury accommodations offer amenities like spacious suites and VIP services. Some of the city's luxury accommodations even feature gigantic penthouses, while others offer tennis courts or salt water pools. Book your luxury experience in Syracuse now, and soon you'll be soaking up luxury in style!