Beginning of main content

location Syracuse is highly rated for Historical Buildings and Cafes by 526 people

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Check prices on hotels in Syracuse

Tonight Tonight Apr 24 - Apr 25
This weekend This weekend Apr 27 - Apr 29
Next weekend Next weekend May 4 - May 6

What are the top landmarks in Syracuse?

Don’t miss these must-see sights and attractions

Top 10 Hotels in Syracuse

See all 795 Hotels in Syracuse
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

Via Vittorio Veneto 93, Syracuse
    4.0 out of 5.0
     
     

    This family-friendly Syracuse hotel is located on the waterfront, within a 10-minute walk of Palazzo Montalto, Temple of Apollo, and Cathedral of Syracuse. Museo ...

    Algila' Ortigia Charme Hotel$210

    Algila' Ortigia Charme Hotel$210
    Antico Hotel Roma 1880

    Antico Hotel Roma 1880

    Via Roma 66, Syracuse
      4.0 out of 5.0
       
       

      Located in Ortigia, this romantic hotel is steps from Church of St. Mary of the Immaculate Conception and Cathedral of Syracuse. Temple of Apollo and Museo Archeologico ...

      Antico Hotel Roma 1880$166

      Antico Hotel Roma 1880$166
      Royal Maniace Hotel

      Royal Maniace Hotel

      Lungomare di Ortigia,13, Syracuse
        4.0 out of 5.0
         
         

        Located in Ortigia, this romantic hotel is within a 10-minute walk of Palazzo Bellomo Regional Gallery and Cathedral of Syracuse. Temple of Apollo and Museo ...

        Royal Maniace Hotel$103

        Royal Maniace Hotel$103
        UNA Hotel One

        UNA Hotel One

        Via Diodoro Siculo 4, Syracuse
          4.0 out of 5.0
           
           

          Located in Grottasanta, this spa hotel is within 1 mi (2 km) of Capuchin Quarry and Museo Archeologico Regionale Paolo Orsi. Archaeological Park of Neapolis ...

          UNA Hotel One$92

          UNA Hotel One$92
          Grande Albergo Alfeo

          Grande Albergo Alfeo

          Via Nino Bixio 5, Syracuse
            4.0 out of 5.0
             
             

            Located in Santa Lucia, this hotel is within a 10-minute walk of Syracuse Forum Ruins and Temple of Apollo. Cathedral of Syracuse and Museo Archeologico Regionale ...

            Grande Albergo Alfeo$109

            Grande Albergo Alfeo$109
            Grand Hotel Villa Politi

            Grand Hotel Villa Politi

            Via Maria Politi Laudien 2, Syracuse
              4.0 out of 5.0
               
               

              Located in Grottasanta, this romantic hotel is within a 15-minute walk of Santa Lucia al Sepolcro Basilica and Museo Archeologico Regionale Paolo Orsi. Archaeological ...

              Grand Hotel Villa Politi$104

              Grand Hotel Villa Politi$104
              Grand Hotel Ortigia Siracusa

              Grand Hotel Ortigia Siracusa

              Viale Mazzini, 12, Syracuse
                5.0 out of 5.0
                 
                 

                This family-friendly Syracuse hotel is located on the boardwalk, within a 5-minute walk of Porta Marina and Temple of Apollo. Cathedral of Syracuse and Museo ...

                Grand Hotel Ortigia Siracusa$230

                Grand Hotel Ortigia Siracusa$230
                Grand Hotel Des Etrangeres

                Grand Hotel Des Etrangeres

                Passeggio Adorno 10/12, Syracuse
                  5.0 out of 5.0
                   
                   

                  Located in Ortigia, this luxury hotel is steps from Tropical Aquarium of Syracuse and Cathedral of Syracuse. Temple of Apollo and Museo Archeologico Regionale ...

                  Grand Hotel Des Etrangeres$179

                  Grand Hotel Des Etrangeres$179
                  Caiammari Boutique Hotel & Spa

                  Caiammari Boutique Hotel & Spa

                  Via Daniele Impellizzeri, Syracuse
                    4.0 out of 5.0
                     
                     

                    This family-friendly Fanusa hotel is located near the beach, within 2 mi (3 km) of Terrauzza Beach and Fanusa Beach. Ciane River and Saline Nature Reserve and ...

                    Caiammari Boutique Hotel & Spa$80

                    Caiammari Boutique Hotel & Spa$80
                    Mercure Siracusa Prometeo

                    Mercure Siracusa Prometeo

                    Viale Teracati 20, Syracuse
                      4.0 out of 5.0
                       
                       

                      Located in Neapolis, this hotel is within a 10-minute walk of San Nicolo dei Cordari, Museo Archeologico Regionale Paolo Orsi, and Archaeological Park of Neapolis. ...

                      Mercure Siracusa Prometeo$97

                      Mercure Siracusa Prometeo$97
                      Map

                      Recent Reviews in Syracuse