Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Texas Medical Center Family Hotels

See all 570 Hotels in Texas Medical Center
Courtyard by Marriott Houston Medical Center

Courtyard by Marriott Houston Medical Center

Houston Medical Center, Houston
3.0 out of 5.0
4.5 out of 5 (1,632 reviews)
Nice but no hot water in amVery nice hotel with great amenities like shuttle to NRG. Very nice lobby with Starbucks. Would have rated higher except I couldn’t shower at 7:30 in the morning to start my day because there wasn’t any hot water to shower with.
  Nov 16, 2017

$84

$84
Wyndham Houston - Medical Center Hotel and Suites

Wyndham Houston - Medical Center Hotel and Suites

6800 Main Street, Houston
3.5 out of 5.0
3.9 out of 5 (1,468 reviews)
Hotel close to all transit systemsGreat area, surrounded by the Medical Centers, Museums of Arts and churches. Walkable area. park across the street from the hotel. Eateries and shopping centers in the immediate area. Within one mile of this hotel. No free shuttle from the hotel to the airport. Lyft and Uber services are ...
  Nov 9, 2017

$98

$98
Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District

6580 Fannin Street, Houston
4.0 out of 5.0
4.3 out of 5 (671 reviews)
Easy access to TMC.Perfect location if attending the TMC or any of the nearby health facilities.
  Oct 22, 2017

$119

$119
Hilton Houston Plaza / Medical Center

Hilton Houston Plaza / Medical Center

6633 Travis St, Houston
3.5 out of 5.0
4.3 out of 5 (488 reviews)
Houston short tripGreat room ( suite style) close to Rice university, restaurants and shops (Rice Village). 20 minute ride to Galleria Mall, 10 minute ride to Downtown. close to Metro Rail too.
  Nov 1, 2017

$105

$105
SureStay Plus Hotel by Best Western Houston Medical Center

SureStay Plus Hotel by Best Western Houston Medical Center

6700 S Main Street, Houston
2.5 out of 5.0
3.5 out of 5 (439 reviews)
Close to hospital Staff was very friendly Plenty of space I got only 1 complaint, when we went back to our room after breakfast our key wouldn’t work & it was just 10:00am maid had to unlock our door, other than that I would stay again
  Nov 11, 2017

$99

$99
Extended Stay America -Houston-Med Ctr-NRG Pk-Braeswood Blvd

Extended Stay America -Houston-Med Ctr-NRG Pk-Braeswood Blvd

1301 Braeswood Blvd, Houston
2.5 out of 5.0
3.2 out of 5 (638 reviews)
Great location for Tx Med CenterGreat location for access to the TX Med Center. Comfortable hotel for a very reasonable price. Friendly staff too.
  Oct 14, 2017

$76

$76
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

5701 Main Street, Houston
4.0 out of 5.0
4.5 out of 5 (1,413 reviews)
Very nice hotel Godbplace to stay. It is at the museum distict. Walking distance to museums. Few miles away from downtown.
  Nov 4, 2017

$230

$230
Sleep 'N Go Hotel Houston Medical Center

Sleep 'N Go Hotel Houston Medical Center

1025 Swanson Street, Houston
2.5 out of 5.0
3.7 out of 5 (279 reviews)
Please it's a suggestion if the name or any similar thing changed from the booking time please send an email to customers so they will be knowing prior ahead of reaching, that only thing gave us a little trouble
  Jul 13, 2017
Americas Best Value Inn-Medical Center Downtown

Americas Best Value Inn-Medical Center Downtown

2419 Riverside Dr, Houston
2.0 out of 5.0
3.3 out of 5 (740 reviews)
Good hotel for Good priceCould not get the water in the shower to warm. You either had freezing or hot water. Clean, quiet and helpful staff. Close to medical centers downtown.
  Nov 17, 2017

$70

$70
Rodeway Inn And Suites Medical

Rodeway Inn And Suites Medical

6712 Morningside Dr, Houston
2.0 out of 5.0
2.8 out of 5 (159 reviews)
Nice Hotel For Visiting Medical CenterStayed here for a conference at the medical center. Compared to the alternatives: 1. It is 15min walk from medical center, the alternatives will be actually on the campus. 2. It is at least half the price of the hotels on the campus. 3. It is in a nice quiet environment, with palm trees and a residential ...
  Nov 4, 2015
Map

Recently booked Family Hotels in Texas Medical Center

Hotel ZaZa Houston
4.0 out of 5.0
Last booking: 3 hours ago
Quality Inn & Suites NRG Park - Medical Center
2.5 out of 5.0
Last booking: 5 hours ago
Extended Stay America -Houston-Med Ctr-NRG Pk-Braeswood Blvd
2.5 out of 5.0
Last booking: 5 hours ago
SpringHill Suites Houston Medical Center/NRG Park
3.0 out of 5.0
Last booking: 6 hours ago
Wyndham Houston - Medical Center Hotel and Suites
3.5 out of 5.0
Last booking: 7 hours ago
Motel 6 Houston NRG Park - Reliant Stadium
2.0 out of 5.0
Last booking: 11 hours ago
Best Western Plaza Hotel & Suites At Medical Center
2.5 out of 5.0
Last booking: 17 hours ago
Houston Marriott Medical Center
4.0 out of 5.0
Last booking: 17 hours ago
Holiday Inn Houston S - Nrg Area - Medical Center
3.0 out of 5.0
Last booking: 17 hours ago

Ready for a vacation your family will look back fondly on in the years to come? Now's the time to get your fam together to see why so many travelers like you have booked a trip to Texas Medical Center this year. This destination is rapidly gaining interest from travelers, and when you plan a getaway here, you and your crew will find out why this place is so noteworthy. You and your relatives will find plenty of time to bond and spend quality time together, and who knows, you may even meet some vacationing families or locals during your stay!

Pinpoint the Greatest Texas Medical Center Family Hotel

It's time to get this family vacation started! At Expedia.com, we offer countless hotel options, so you have a number to sort through until you find the ideal one for your family. From roomy interiors to places with friendly service, you'll come across exactly what your fam desires. No matter what kind of family vacation you're in search of, you'll find the ideal spot to temporarily call home.

Families from near and far are venturing to Texas Medical Center to see why this destination is quickly climbing the popularity ranks. In fact, this place saw lots of vacationers last year, and now you can find helpful tips and recommendations in our review section. You'll be blown away at how many people would suggest that others stay at the same place as them! As soon as you open the door to your room, you'll see why these places were so well received. The rooms are clean and tidy, while the property grounds are especially appealing. From nice rooms to even nicer hotel staff, your family will be well on its way to being spoiled.

When you look at the year before, more people booked a trip in Texas Medical Center this year, proving that it's a great choice for a family romp. The time is now to show your family how much you love them, and you never know, it just might become a new family tradition. Make reservations for your Texas Medical Center family hotel and get ready to accept some major parent props!