Find spa resorts & hotels in Texas Medical Center, Houston from $144

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Top Texas Medical Center Resorts & Hotels with Spas

Blossom Hotel Houston, Curio Collection by Hilton

4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (3597)
"Everything about our stay was excellent. "
United States
Clarence
$123 nightly
The price is $144
Dec 15 - Dec 16
Total with taxes and fees
Blossom Hotel Houston, Curio Collection by Hilton

Hilton Americas-Houston

4.0 star property
Downtown Houston
9.4 out of 10, Exceptional, (1584)
"Clean, great location and super convenient food options!"
United States
Valerie
$143 nightly
The price is $167
Jan 1 - Jan 2, 2026
Total with taxes and fees
Hilton Americas-Houston

JW Marriott Houston Downtown

5.0 star property
Downtown Houston
9.0 out of 10, Wonderful, (1002)
"Love the room very kind personal at the check in. "
United States
Antonia
$198 nightly
The price is $231
Dec 19 - Dec 20
Total with taxes and fees
JW Marriott Houston Downtown

Omni Houston Hotel

4.0 star property
Greater Uptown
9.0 out of 10, Wonderful, (1007)
"Great location! "
United States
Fletcher
$162 nightly
The price is $189
Dec 14 - Dec 15
Total with taxes and fees
Omni Houston Hotel

The Laura Hotel, Houston Downtown, Autograph Collection

4.5 star property
Downtown Houston
9.0 out of 10, Wonderful, (1038)
"I would stay at this hotel again "
United States
Domonique
$182 nightly
The price is $213
Dec 11 - Dec 12
Total with taxes and fees
The Laura Hotel, Houston Downtown, Autograph Collection

Marriott Marquis Houston

4.0 star property
Downtown Houston
9.0 out of 10, Wonderful, (1009)
"Completely loved our stay at this location. "
United States
Miriam
$211 nightly
The price is $246
Jan 1 - Jan 2, 2026
Total with taxes and fees
Marriott Marquis Houston

Four Seasons Hotel Houston

5.0 star property
Downtown Houston
9.2 out of 10, Wonderful, (1002)
"Just beautiful. I recommend"
United States
LYDIA CHISOM
$414 nightly
The price is $485
Jan 3 - Jan 4, 2026
Total with taxes and fees
Four Seasons Hotel Houston

Hotel ZaZa Houston Memorial City

4.0 star property
Memorial
9.4 out of 10, Exceptional, (1005)
"Beautiful hotel, amazing customer service and it was so comfy. "
United States
Amber
$269 nightly
The price is $315
Dec 14 - Dec 15
Total with taxes and fees
Hotel ZaZa Houston Memorial City

Thompson Houston, by Hyatt

4.0 star property
Fourth Ward
9.4 out of 10, Exceptional, (221)
"The rooms were very clean and well appointed."
United States
John
$279 nightly
The price is $326
Dec 14 - Dec 15
Total with taxes and fees
Thompson Houston, by Hyatt

The Post Oak Hotel at Uptown Houston

5.0 star property
The Galleria
9.6 out of 10, Exceptional, (881)
"Beautiful hotel "
United States
nabintou
$485 nightly
The price is $568
Dec 21 - Dec 22
Total with taxes and fees
The Post Oak Hotel at Uptown Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Texas Medical Center

Top Texas Medical Center attractions for a relaxing vacation

In the heart of the Texas Medical Center, travelers seeking rejuvenation and relaxation will find an inviting array of spa hotels that cater to their every need. Start your journey by exploring the Houston Museum District, just a short drive away, where art enthusiasts can immerse themselves in world-class exhibits at the Museum of Fine Arts, Houston or the Houston Museum of Natural Science. For a breath of fresh air, visit Hermann Park, a picturesque green space featuring serene walking trails, a scenic lake, and even a Japanese garden—perfect for a peaceful morning stroll. Just steps from your hotel, indulge in a culinary experience at The Medical Center's renowned restaurants, many of which offer health-conscious menus that complement your wellness getaway. Don't miss the opportunity to unwind at the nearby Houston Zoo, where you can connect with nature and maybe even book a behind-the-scenes tour for a unique adventure. When returning to your hotel, expect to be pampered with luxurious spa services, from soothing massages to invigorating facials, ensuring you leave feeling refreshed and revitalized. Each stay in this vibrant neighborhood promises attentive service and a perfect blend of relaxation and exploration, making it an excellent choice for travelers.

Find the best hotels & resorts with spas in Texas Medical Center

For those seeking relaxation and rejuvenation in Texas Medical Center, Houston, these hotels offer exceptional spa experiences that cater to wellness enthusiasts.

Hilton Garden Inn Houston Medical Center, TX

  • Why it's great for tailored spa getaway: Ideal for guests seeking a balance of comfort and accessibility, Hilton Garden Inn Houston Medical Center offers spa access in a welcoming place, reflected in its impressive review rating of 9.4. While the spa is accessible, the hotel also offers wellness with a range of fitness facilities and a refreshing outdoor pool for guests looking to maintain their health routines during their stay.
  • Other amenities: Guests can enjoy features like free area shuttle service, a 24-hour fitness center, and complimentary breakfast options. The hotel also provides accessible self-parking, daily housekeeping, and a dog exercise area, ensuring a convenient stay. With a concierge service available, guests can easily navigate the local area and explore nearby attractions.
  • Neighborhood: Texas Medical Center
  • Nearby attractions: Hermann Park - 0.18 miles, Houston Zoo - 1.04 miles

InterContinental Houston by IHG

  • Why it's great for tailored spa getaway: The InterContinental Houston by IHG is perfect for travelers seeking a luxurious experience with spa accessibility, a solid review rating of 9.2. This upscale hotel provides a serene ambiance where guests can indulge in restorative spa treatments while enjoying exceptional service throughout their stay.
  • Other amenities: Beyond the spa, the hotel features a beautiful outdoor pool, fitness facilities open 24 hours, and valet parking. Guests can relax on the terrace or patio, and enjoy the convenience of electric car charging stations. With designer toiletries and premium bedding in every room, comfort is paramount. The hotel also offers early check-in and late check-out options to enhance the guest experience.
  • Neighborhood: Texas Medical Center
  • Nearby attractions: MD Anderson Cancer Center - 0.69 miles

Blossom Hotel Houston

  • Why it's great for tailored spa getaway: Blossom Hotel Houston is an oasis for travelers looking to unwind, featuring a remarkable spa experience with a guest review rating of 9.0. The hotel boasts a full-service spa offering a variety of treatments, including Swedish and deep tissue massages, as well as prenatal massage options, ensuring every guest can find their perfect relaxation remedy.
  • Other amenities: In addition to its outstanding spa services, guests can enjoy an outdoor pool with sun loungers, a fitness center open 24 hours, and complimentary designer toiletries in their rooms. The hotel also features bathrobes for added comfort, valet parking for convenience, and rooftop terrace access for stunning views. With early check-in and late check-out options available, guests can maximize their relaxation time.
  • Neighborhood: Texas Medical Center
  • Nearby attractions: MD Anderson Cancer Center - 0.84 miles

Top Texas Medical Center Hotel Reviews

Frequently asked questions

Looking to vacation at a spa hotel in Texas Medical Center?
Forget the stress of everyday life and book yourself a lush spa hotel. Check out the museums and restaurants in Texas Medical Center—your day trip starts here. Be sure to enjoy the shopping during your stay. Spa hotels are a great way to break away from your daily routine and add a layer of luxury to your vacation.
What is the best spa hotel in Texas Medical Center?
Blossom Hotel Houston, Curio Collection by Hilton is a top spa hotel featuring a rooftop terrace, a 24-hour fitness center, an outdoor pool, and a restaurant. Spend an afternoon at the spa where you'll find facials, Swedish massages, and deep-tissue massages.
How many spa hotels are there in Texas Medical Center?
Among Expedia's 181 accommodation options in Texas Medical Center, there is 1 spa hotel.
What's there to see and do in Texas Medical Center?
Enjoy all that Texas Medical Center has to offer when you visit Houston Zoo, NRG Stadium, and Toyota Center. If you have extra time while you're in the area, you might want to stop by Houston Natural Science Museum and NRG Astrodome.
What is a Texas Medical Center spa hotel?
Spa hotels in Texas Medical Center have full on-site spas offering services like couples massages and a selection of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your vacation.

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