Twain Vacations from $445

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Your Twain Vacation

Take the stress out of organizing your next escape by booking a Twain vacation package. Soak in the sounds and sights of this enticing neighborhood and experience everything it has to offer. If you're all about sightseeing, no trip to Twain is complete without stopping by nearby Pleasant Valley Golf Course. Don't just wish for it — make it a reality! Book your ideal Twain vacation with Expedia and get to where you're going your way.

The Latest Twain Vacation Packages

Price found within the past 48 hours. Click for updated prices.
American Inn Cedar Rapids South

American Inn Cedar Rapids South

2 out of 5
Southwest Area
Price was $501, price is now $445 per person
$445
per person
May 8 - May 10
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Cedar Rapids (CID)
7.6/10 Good! (329 reviews)
Clean rooms and stay was great

Reviewed on Mar 9, 2026

The Hotel at Kirkwood Center

The Hotel at Kirkwood Center

3.5 out of 5
Price was $662, price is now $554 per person
$554
per person
May 1 - May 4
found 21 hours ago
Roundtrip flight included
Denver (DEN) to Cedar Rapids (CID)
9.8/10 Exceptional! (732 reviews)
Very nice hotel. Clean rooms.

Reviewed on Mar 2, 2026

Hotel Millwright

Hotel Millwright

3 out of 5
Price was $571, price is now $504 per person
$504
per person
May 8 - May 10
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Cedar Rapids (CID)
9.6/10 Exceptional! (1,003 reviews)
The staff was great and the room was really nice! The only thing I noticed was that the hallways echoed a lot, especially when people walked around or used the ice machine, which was close to our room. This caused me to wake up throughout the night, but I think it was because of where our room was located. Other than that, I’d highly recommend!

Reviewed on Mar 1, 2026

Cobblestone Inn & Suites - Vinton

Cobblestone Inn & Suites - Vinton

2.5 out of 5
Price was $574, price is now $531 per person
$531
per person
Apr 17 - Apr 20
found 20 hours ago
Roundtrip non-stop flight included
San Juan (SJU) to Cedar Rapids (CID)
8.6/10 Excellent! (302 reviews)
Rooms were clean. Beds comfortable.

Reviewed on Jan 31, 2026

Residence Inn by Marriott Coralville

Residence Inn by Marriott Coralville

3 out of 5
Price was $503, price is now $473 per person
$473
per person
May 8 - May 10
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Cedar Rapids (CID)
8.4/10 Very Good! (492 reviews)
Staff is always welcoming. Nice rooms, always clean and smell good. Huge breakfast and it's always yummy. I always enjoy my stay and end up coming back. Thanks staff for everything.

Reviewed on Jan 24, 2026

Where to stay in Twain

Find the best Twain areas and neighborhoods for the activities you enjoy most. Learn more about Twain
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Downtown

2 out of top 10 points of interest in this area

If you're spending some time in Downtown, Iowa City Public Library and The Englert Theater are top sights worth seeing.

Find hotels in Downtown

Twain Hotel Deals

Lovely 3BR Close to Downtown

Lovely 3BR Close to Downtown

Iowa City IA
$251 nightly
The price is $281 total per night from Apr 2 to Apr 3
$281 total
Apr 2 - Apr 3
Total with taxes and fees
10/10 Exceptional! (34 reviews)
The kitchen is good sized & the dining room table has a large leaf, so we were able to roast a turkey with many side dishes & host another couple to a great Christmas dinner.

Reviewed on Dec 28, 2025

Lovely 3BR Close to Downtown
Hyatt Place Iowa City Downtown

Hyatt Place Iowa City Downtown

3 out of 5
255 E Court St Iowa City IA
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $101 total per night from Mar 23 to Mar 24
$101 total
Mar 23 - Mar 24
Total with taxes and fees
9.2/10 Wonderful! (1,413 reviews)
Best breakfast I've had in months

Reviewed on Mar 11, 2026

Hyatt Place Iowa City Downtown
Graduate by Hilton Iowa City

Graduate by Hilton Iowa City

4 out of 5
210 S Dubuque St Iowa City IA
Fully refundable
$93 nightly
The price is $105 total per night from Mar 22 to Mar 23
$105 total
Mar 22 - Mar 23
Total with taxes and fees
9.2/10 Wonderful! (1,023 reviews)
Great access to the gym. Bar and breakfast attached to the hotel. Helpful, friendly staff. Had to go to the front desk for TP and hand soap. Received what I needed but should have been in the room. Not a deal breaker but an obvious thing that could be corrected.

Reviewed on Mar 13, 2026

Graduate by Hilton Iowa City
See all 155 properties in Twain
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Twain

The Old Iowa Capitol

University of Iowa

Explore the campus of University of Iowa, during your trip to Iowa City. You can attend a sporting event while in the area.

University of Iowa
U of iowa

University of Iowa Hospital and Clinics

Though University of Iowa Hospital and Clinics might be what brings you to town, perhaps you'll have a chance to explore more of Iowa City while you are here.

University of Iowa Hospital and Clinics
The old Capitol Building and museum in Iowa City, Iowa, USA.

Iowa Old Capitol Building

You can find out about the history of Iowa City with a trip to Iowa Old Capitol Building. You can attend a sporting event while in the area.

Iowa Old Capitol Building
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.